- Erratum: Pharmacokinetics and bioequivalence of two different 20 mg olmesartan tablets: A randomized, single-dose, two-period crossover study in healthy Korean male volunteers
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Lee J, Kim A, Yu KS, Chung JY, Yim SV, Kim BH
- KMID: 2290478
- Transl Clin Pharmacol.
- 2016 Jun;24(2):111-111.
- doi: 10.12793/tcp.2016.24.2.111
In the published version of this article, an error in the sponsor's identity was discovered in the acknowledgment section. -
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- A Foundation for a “Cheerful Society”: The Korean War and the Rise of Psychiatry
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Shin JH, Yim SV
- KMID: 2545724
- Korean J Med Hist.
- 2023 Aug;32(2):553-591.
- doi: 10.13081/kjmh.2023.32.553
One of the most remarkable medical achievements of the Korean War was the development of psychiatry. During the Korean War, soldiers and prisoners of war (POWs) experienced “gross stress reaction”... -
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- A Study on the Effects of Taking the Drink Containing Benzoic Acid on Analysis of Hippuric Acid in Urine
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Jung CD, Kim SW, Park JB, Yim SV
- KMID: 2298541
- Korean J Aerosp Environ Med.
- 2000 Sep;10(3):235-240.
BACKGROUND: Benzoic acid contained in some food can hinder the biological monitoring of hippuric acid in urine, which is frequently used as an exposure index of toluene and xylene. METHOD:... -
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- Indomethacin induces apoptosis in NCI-H1299 human lung carcinoma cells
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Kim BS, Kim SA, Kim MJ, Lee HJ, Park SJ, Jung JC, Kim CJ, Yim SV, Chung JH
- KMID: 2285238
- Korean J Physiol Pharmacol.
- 2001 Apr;5(2):177-181.
Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been found to be useful in the chemoprevention of colon cancer. To investigate whether indomethacin, an NSAIDs, induces apoptosis and thus assess the possibility of its application... -
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- Repeated Administration of Newly Synthesized Aceclofenac Sustained Release Form Causes Agranulocytosis: Case Report of an Unforeseen Adverse Event during the Phase 1 Trial
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Jin H, Zheng R, Kim B, Yim SV
- KMID: 2317852
- Transl Clin Pharmacol.
- 2014 Jun;22(1):11-12.
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAIDs) for inflammatory diseases. In this report, we report a serious adverse event (AE) occurred during the phase I clinical trial for a new... -
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- Changes in Human Gene Expression After Sleep Deprivation
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Sun JY, Kim JW, Yim SV, Oh M, Kang WS
- KMID: 2528448
- Korean J Biol Psychiatry.
- 2022 Apr;29(1):9-14.
- doi: 10.22857/kjbp.2022.29.1.002
Objectives: Sleep is fundamental to maintaining homeostatic control and has behavioral and psychological effects on humans. To better understand the function and pathophysiology of sleep, specific gene expressions in reference... -
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- Screening study for genetic polymorphisms affecting pharmacokinetics of simvastatin
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Im S, Kim BH, Lee K, Kwack K, Yim SV
- KMID: 2383599
- Transl Clin Pharmacol.
- 2016 Mar;24(1):43-54.
- doi: 10.12793/tcp.2016.24.1.43
Simvastatin reduces plasma cholesterol by inhibiting HMG-CoA reductase (HMGR) and is widely used in the treatment of hypercholesterolemia. To screening the possible genetic factors affecting the pharmacokinetics (PK) of simvastatin,... -
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- Association of Glutatione S-Transferase (GSTM1 and GSTT1) Gene Deletions in Korean Patients with Alcoholism
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Tai ZL, Uhm YK, Kim JW, Yim SV
- KMID: 2165294
- Exp Neurobiol.
- 2009 Jun;18(1):32-36.
- doi: 10.5607/en.2009.18.1.32
Alcoholism is caused by a complex interaction between genetic and environmental factors. Findings obtained from several studies indicate that some tissue damage occurring in alcohol abusers is due to the... -
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- Neuroprotective Effects of Intraischemic(1 hour) Moderate Hypothermia in Gerbil Brain Global Ischemic Model
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Kim IB, Jung KC, Yim SV, Jang SJ, Kim SW
- KMID: 1543436
- J Korean Soc Emerg Med.
- 1999 Sep;10(3):350-362.
BACKGROUND: In animal models of cerebral ischemic-reperfusion has been shown to have a beneficial effect. The object of this study is to compare the effect of pathologic findings between normotheimic... -
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- Apo-1/Fas (CD95) Gene Polymorphism in Korean Knee Osteoarthritis Patients
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Hong SJ, Yang HI, Yim SV, Chung JH, Jung YO, Kim HY
- KMID: 2150580
- Immune Netw.
- 2003 Jun;3(2):145-149.
- doi: 10.4110/in.2003.3.2.145
BACKGROUND: Apoptosis has been implicated in pathogenesis of various disease. Apo-1/Fas (CD95) is one of the main pathway of apoptosis. To examine the possible relationship between Apo-1/Fas (CD95) and primary... -
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- Two dinucleotide repeat polymorphisms (AC/TG and GT/CA) in the 5' upstream region of the mouse tryptophan hydroxylase gene
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Yim SV, Chi SG, Chung SH, Lee HJ, Kim MJ, Park SJ, Jung JC, Chung JH
- KMID: 2071551
- Korean J Physiol Pharmacol.
- 1999 Oct;3(5):501-505.
Tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin biosynthesis, is primarily expressed in serotonergic neurons of the raphe nuclei. Simple tandem repeat polymorphisms, typically one to four nucleotides long, are tandemly repeated several... -
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- A bioequivalence study of two levofloxacin tablets in healthy male subjects
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Chung I, Yoon S, Yi S, Kim BH, Yim SV, Jang IJ, Lee H
- KMID: 2050943
- Transl Clin Pharmacol.
- 2014 Dec;22(2):102-105.
- doi: 10.12793/tcp.2014.22.2.102
Levofloxacin is a bactericidal broad spectrum antibiotic against Gram-positive and Gram-negative pathogens. A randomized, two-treatment, two-period, two-way crossover study was conducted to evaluate the bioequivalence of Lectacin 250 mg tablet,... -
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- Role of Caveolin-1 in Indomethacin-induced Death of Human Hepatoadenocarcinoma SK-Hep1 Cells
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Kim KN, Kang JH, Yim SV, Park CS
- KMID: 1838351
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):143-148.
- doi: 10.4196/kjpp.2008.12.4.143
Caveolin-1 (CAV1) is an integral membrane protein that may function as a scaffold for plasma membrane proteins and acts as a tumor suppressor protein. One causative factor of chemotherapy- resistant... -
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- The Efficacy of Shikonin on Cartilage Protection in a Mouse Model of Rheumatoid Arthritis
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Kim YO, Hong SJ, Yim SV
- KMID: 2285403
- Korean J Physiol Pharmacol.
- 2010 Aug;14(4):199-204.
- doi: 10.4196/kjpp.2010.14.4.199
The potential therapeutic action of shikonin in an experimental model of rheumatoid arthritis (RA) was investigated. As a RA animal model, DBA/1J mice were immunized two times with type II... -
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- Bioequivalence of the pharmacokinetics between two formulations of 0.2 mg tamsulosin hydrochloride in healthy subjects
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Park SI, Rhee SJ, Jang IJ, Yu KS, Yim SV, Kim BH
- KMID: 2148855
- Transl Clin Pharmacol.
- 2015 Jun;23(1):21-25.
- doi: 10.12793/tcp.2015.23.1.21
Tamsulosin is an effective therapeutic option for lower urinary tract symptoms, as it selectively blocks alpha1A- and alpha1D-adrenoceptors in the bladder and prostate. The purpose of this study was to... -
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- Apo-1/Fas (CD95) Gene Polymorphism in Korean Hepatocellular Carcinoma Patients
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Kim SS, Hong SJ, Ahn YG, Kim BS, Yuh YJ, Han KY, Lee HJ, Chung JH, Yim SV, Cho J, Park YH
- KMID: 1607351
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):29-31.
It is well known that different expression of Apo-1/Fas (CD95) plays important roles in various tumors and hepatocellular carcinoma (HCC) pathogenesis. Apo-1/Fas mediated apoptosis is one of the important pathways... -
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- Proteinuria after Gravitational Acceleration Tolerance Training
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Lee YJ, Yim SV, Lee MH
- KMID: 2225893
- Korean J Clin Pathol.
- 1999 Dec;19(6):624-628.
BACKGROUND: Fighter pilots are frequently exposed to high gravitational acceleration force acting along the body axis from the head to the feet (+GZ) and this gravitational force causes considerable strain... -
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- Selective cytotoxicity of a novel platinum (II) coordination complex on human gastric cancer cell lines and normal kidney cells
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Jung JC, Kim YK, Yim SV, Park SJ, Chung JH, Chang SG, Lee KT, Rho YS
- KMID: 2285222
- Korean J Physiol Pharmacol.
- 1999 Jun;3(3):283-291.
We have synthesized novel platinum (II) coordination complex containing cis-1,2-diaminocyclohexane (DACH) as a carrier ligand and 1,2-bis(diphenylphosphino)ethane (DPPE) as leaving group. Furthermore, nitrate was added to improve the water-solubility. A new series of (Pt(cis-DACH)(DPPE))... -
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- Bioequivalence study of Donepezil hydrochloride in healthy Korean volunteers
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Choi Y, Rhee SJ, Jang IJ, Yu KS, Yim SV, Kim BH
- KMID: 2148856
- Transl Clin Pharmacol.
- 2015 Jun;23(1):26-30.
- doi: 10.12793/tcp.2015.23.1.26
Donepezil is a centrally acting, reversible acetylcholinesterase inhibitor that is widely used for treating Alzheimer's disease. This study aimed to compare the pharmacokinetics of Bastia(R), a test tablet formulation of... -
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- Impact of Glutathione S-Transferase M1 and T1 Gene Polymorphisms on the Smoking-Related Coronary Artery Disease
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Kim SJ, Kim MG, Kim KS, Song JS, Yim SV, Chung JH
- KMID: 1786870
- J Korean Med Sci.
- 2008 Jun;23(3):365-372.
- doi: 10.3346/jkms.2008.23.3.365
Glutathione S-transferase (GST) plays a key role in the detoxification of xenobiotic atherogen generated by smoking. To analyze the effect of GSTM1/T1 gene polymorphisms on the development of smoking-related coronary... -
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