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Pancreatic Tuberculosis Presenting with Pancreatic Cystic Tumor: A Case Report and Review of the Literature

Cho SB

Pancreatic tuberculosis is a rare clinical entity, presenting as malignancy mimicking pancreatic mass. Therefore, it represents a diagnostic challenge. To date, ten cases have been reported in Korea. I report...
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Current Issues on Molecular and Immunological Diagnosis of Tuberculosis

Cho SN

aboratory diagnosis of tuberculosis (TB) traditionally relies on smear microscopy and culture of Mycobacterium tuberculosis from clinical samples. With recent advances in technology, there have been numerous efforts to develop...
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A Case of Gallbladder Tuberculosis Diagnosed by Positive Tuberculosis-Polymerase Chain Reaction

Ryu MJ, Jeon TJ, Park JY, Choi Y, Baek SS, Sinn DH, Oh TH, Kim JY

Gallbladder tuberculosis is an extremely rare disease that is rarely reported in the literature. Arriving at the correct diagnosis of gallbladder tuberculosis is difficult, and it is usually made by...
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Analysis of Patients with Positive Acid-fast Bacilli Culture and Negative T-SPOT.TB Results

Han YM, Kim HS, Kim CH, Kang HJ, Lee KM

BACKGROUND: T-SPOT.TB is a sensitive test that detects interferon-gamma producing T-cells in tuberculosis patients following stimulation with tuberculosis-specific antigens. Our study was aimed to investigate the possible causes of false...
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Clinical Usefulness of T-SPOT.TB Test for the Diagnosis of Tuberculosis

Kim HS, Kim CH, Hur M, Hyun IG, Park MJ, Song W, Park JY, Kang HJ, Lee KM

BACKGROUND: Tuberculosis-specific ELISPOT assay (T-SPOT.TB, Oxford Immunotec, UK) is a test that detects interferon-gamma producing T-cells after stimulating patient's lymphocytes with two kinds of tuberculosis-specific antigens (ESAT-6 and CFP-10). We...
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Production of monoclonal antibodies to lipoarabinomannan-B and use in the detection of mycobacterial antigens in sputum

Cho SN, Shin JS, Kim JD, Chong Y

Tuberculosis has traditionally been confirmed by AFB staining or culturing Mycobacterium tuberculosis from clinical specimens. However, because of the low sensitivity of the sputum smear examination and of the delayed...
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Multiparametric Magnetic Resonance Imaging Characteristics of Prostate Tuberculosis

Cheng Y, Huang L, Zhang X, Ji Q, Shen W

OBJECTIVE: To describe the multiparametric magnetic resonance imaging (MRI) appearance of prostate tuberculosis. MATERIALS AND METHODS: Six patients with prostate tuberculosis were analyzed retrospectively. The mean age of the patients was...
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Description of Pediatric Tuberculosis Evaluated in a Referral Center in Istanbul Turkey

Gulec SG, Telhan L, Kockaya T, Erdem E, Bayraktar , Palanduz A

PURPOSE: Diagnosis of tuberculosis (TB) in children is more challenging than in adults. This study aimed to describe demographical, clinical and laboratory findings of children diagnosed with tuberculosis in Turkey,...
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Comparative Evaluation of Several Gene Targets for Designing a Multiplex-PCR for an Early Diagnosis of Extrapulmonary Tuberculosis

Raj A, Singh N, Gupta KB, Chaudhary , Yadav A, Chaudhary , Agarwal K, Varma-Basil M, Prasad R, Khuller GK, Mehta PK

PURPOSE: Diagnosis of extrapulmonary tuberculosis (EPTB) poses serious challenges. A careful selection of appropriate gene targets is essential for designing a multiplex-polymerase chain reaction (M-PCR) assay. MATERIALS AND METHODS: We compared...
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A Case of Tuberculous Liver Abscess Developed during Chemotherapy for Tuberculous Peritonitis as Paradoxical Response

Kim TK, Choi CW, Ha JK, Jang HH, Park SB, Kim HW, Kang DH

Tuberculous liver abscesses are rare. Paradoxical response in tuberculosis is common and occurred between 2 weeks and 12 weeks after anti-tuberculous medication. We report here a case of tuberculous liver...
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Rapid Diagnosis of Tuberculosis and Multidrug Resistance Using a MGIT 960 System

Koh WJ, Ko Y, Kim CK, Park KS, Lee NY

BACKGROUND: The purpose of this study was to compare the turnaround time for liquid culturing and primary anti-tuberculous drug susceptibility testing (DST) performed using the mycobacteria growth indicator tube (MGIT)...
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Evaluation of the Performances of AdvanSure TB/NTM Real Time PCR Kit for Detection of Mycobacteria in Respiratory Specimens

Kim YJ, Park MY, Kim SY, Cho SA, Hwang SH, Kim HH, Lee EY, Jeong J, Kim KH, Chang CL

BACKGROUND: PCR is a widely used method for rapid and accurate diagnosis of mycobacteriosis. The sensitivity and specificity of a real time PCR kit newly developed in Korea were evaluated...
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Evaluation of Propidium Monoazide Real-Time PCR for Early Detection of Viable Mycobacterium tuberculosis in Clinical Respiratory Specimens

Kim YJ, Lee SM, Park BK, Kim SS, Yi J, Kim HH, Lee EY, Chang CL

BACKGROUND: Conventional acid-fast bacilli (AFB) staining cannot differentiate viable from dead cells. Propidium monoazide (PMA) is a photoreactive DNA-binding dye that inhibits PCR amplification by DNA modification. We evaluated whether...
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Clinical characteristics and the usefulness of the QuantiFERON-TB Gold In-Tube test in hematologic patients with hepatic or splenic lesions

Kwon JC, Kim SH, Park SH, Choi SM, Lee DG, Choi JH, Yoo JH, Kim YJ, Lee S, Kim HJ, Cho SG, Lee JW, Min WS

BACKGROUND/AIMS: Hepatic or splenic lesions in hematologic patients are not defined well because they are not easy to evaluate due to limitations of invasive procedures. Management typically depends on the...
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18F-FDG Positron-Emission Tomography/Computed Tomography Findings of Radiographic Lesions Suggesting Old Healed Tuberculosis

Jeong YJ, Paeng JC, Nam HY, Lee JS, Lee SM, Yoo CG, Kim YW, Han SK, Yim JJ

The presence of radiographic lesions suggesting old healed tuberculosis (TB) is one of the strongest risk factors for the subsequent development of active TB. We elucidated the metabolic activity of...
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Isolation and Identification of Geosmithia argillacea from a Fungal Ball in the Lung of a Tuberculosis Patient

Sohn JY, Jang MA, Lee JH, Park KS, Ki CS, Lee NY

Geosmithia argillacea, an anamorph of Talaromyces eburneus, is a thermophilic filamentous fungus that has a phenotype similar to that of the Penicillium species, except for the creamy-white colonies and cylindrical...
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Positive Tuberculin Skin Test or Interferon-Gamma Release Assay in Patients with Radiographic Lesion Suggesting Old Healed Tuberculosis

Jeong YJ, Yoon S, Koo HK, Lim HJ, Lee JS, Lee SM, Yang SC, Yoo CG, Kim YW, Han SK, Yim JJ

Radiographic lesions suggesting old healed tuberculosis (TB) is considered a risk factor for the subsequent development of active TB. The aim of this study was to estimate the positive rates...
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