- Decreased expression of Toll-like receptor 4 and 5 during progression of prostate transformation in transgenic adenocarcinoma of mouse prostate mice
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Han JH, Park JH, Kim BY, Chang SN, Kim TH, Park JH, Kim DJ
- KMID: 2344300
- J Vet Sci.
- 2015 Sep;16(3):281-287.
- doi: 10.4142/jvs.2015.16.3.281
Chronic inflammation has been considered an important risk factor for development of prostate cancer. Toll-like receptors (TLRs) recognize microbial moieties or endogenous molecules and play an important role in the... -
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- TLR5 Activation through NF-κB Is a Neuroprotective Mechanism of Postconditioning after Cerebral Ischemia in Mice
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Jeong J, Kim S, Lim DS, Kim SH, Doh H, Kim SD, Song YS
- KMID: 2389008
- Exp Neurobiol.
- 2017 Aug;26(4):213-226.
- doi: 10.5607/en.2017.26.4.213
Postconditioning has been shown to protect the mouse brain from ischemic injury. However, the neuroprotective mechanisms of postconditioning remain elusive. We have found that toll-like receptor 5 (TLR5) plays an... -
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- Association of Toll-Like Receptor 5 Gene Polymorphism with Susceptibility to Ossification of the Posterior Longitudinal Ligament of the Spine in Korean Population
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Chung WS, Nam DH, Jo DJ, Lee JH
- KMID: 1442686
- J Korean Neurosurg Soc.
- 2011 Jan;49(1):8-12.
- doi: 10.3340/jkns.2011.49.1.8
OBJECTIVE: Ossification of the posterior longitudinal ligament (OPLL) has a strong genetic component. Specific gene polymorphisms may be associated with OPLL in several genes which regulate calcification in chondrocytes, change... -
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- Effects of all-trans retinoic acid on expression of Toll-like receptor 5 on immune cells
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Kim KH, Park SJ
- KMID: 2328585
- J Korean Assoc Oral Maxillofac Surg.
- 2010 Dec;36(6):481-489.
INTRODUCTION: TLR-5, a member of the toll-like receptor (TLR) family, is a element of the type I transmembrane receptors, which are characterized by an intracellular signaling domain homolog to the... -
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- Cloning, expression and functional analysis of the duck Toll-like receptor 5 (TLR5) gene
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Cheng Y, Sun Y, Wang H, Shi S, Yan Y, Li J, Ding C, Sun J
- KMID: 2160819
- J Vet Sci.
- 2015 Mar;16(1):37-46.
- doi: 10.4142/jvs.2015.16.1.37
Toll-like receptor 5 (TLR5) is responsible for the recognition of bacterial flagellin in vertebrates. In the present study, the first TLR5 gene in duck was cloned. The open reading frame... -
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- Flagellin Modulates the Function of Invariant NKT Cells From Patients With Asthma via Dendritic Cells
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Shim JU, Rhee JH, Jeong JU, Koh YI
- KMID: 2391040
- Allergy Asthma Immunol Res.
- 2016 May;8(3):206-215.
- doi: 10.4168/aair.2016.8.3.206
PURPOSE: Invariant natural killer T (iNKT) cells play a critical role in the pathogenesis of asthma. We previously reported the association between circulating Th2-like iNKT cells and lung function in... -
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- A Fusion Protein of Derp2 Allergen and Flagellin Suppresses Experimental Allergic Asthma
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Tan W, Zheng JH, Duong TM, Koh YI, Lee SE, Rhee JH
- KMID: 2431857
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):254-266.
- doi: 10.4168/aair.2019.11.2.254
PURPOSE: The house dust mite (HDM) is one of the most important sources of indoor allergens and a significant cause of allergic rhinitis and allergic asthma. Our previous studies demonstrated... -
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- Tetanus toxin fragment C fused to flagellin makes a potent mucosal vaccine
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Lee SE, Nguyen CT, Kim SY, Thi TN, Rhee JH
- KMID: 2049108
- Clin Exp Vaccine Res.
- 2015 Jan;4(1):59-67.
- doi: 10.7774/cevr.2015.4.1.59
PURPOSE: Recombinant subunit vaccines provide safe and targeted protection against microbial infections. However, the protective efficacy of recombinant subunit vaccines tends to be less potent than the whole cell vaccines,... -
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- A Bacterial Flagellin, Vibrio vulnificus FlaB, Induces Human Dendritic Cell Maturation
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Jeong BC, Kim SY, Choi BH, Park MS, Lee JJ, Rhee JH, Lee SE
- KMID: 1574163
- J Bacteriol Virol.
- 2005 Sep;35(3):209-216.
The motile marine bacterium, Vibrio vulnificus has a total of six flagellins. Flagellin is a structural component of flagellar filament in various locomotive bacteria and is the ligand of Toll-like... -
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- Intranasal immunization with a flagellin-adjuvanted peptide anticancer vaccine prevents tumor development by enhancing specific cytotoxic T lymphocyte response in a mouse model
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Nguyen CT, Hong SH, Ung TT, Verma V, Kim SY, Rhee JH, Lee SE
- KMID: 2167723
- Clin Exp Vaccine Res.
- 2013 Jul;2(2):128-134.
- doi: 10.7774/cevr.2013.2.2.128
PURPOSE: Human papillomavirus (HPV) is a significant cause of cervical cancer-related deaths worldwide. Because HPV is a sexually transmitted mucosal pathogen, enhancement of antigen-specific mucosal immune response likely serves good... -
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