- Differential Regulation of Antioxidant Enzymes during Monocyte Differentiation
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Lee YS, Kang SS, Kim EJ
- KMID: 1547852
- Korean J Immunol.
- 1997 Mar;19(1):121-128.
Antioxidant enzymes levels were determined in monocytes during phorbol myristate acetate (PMA)-induced differentiation. PMA induced the differentiation of a human monocytic leukemia cell line THP-1 into macrophage-like cells as indicated... -
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- Thapsigargin Increases IL-2 Production in T Cells at Nanomolar Concentrations
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Kim KH, Kim SH, Jung HH, Moon JH, Jeong SU, Yu K, Lee CK
- KMID: 2419771
- Immune Netw.
- 2018 Aug;18(4):e26.
- doi: 10.4110/in.2018.18.e26
Thapsigargin (TGN) is a potent and selective inhibitor of sarco-endoplasmic Ca²âº-ATPase, leading to rapid elevation of cytoplasmic Ca2+ concentration. Previous reports have shown that TGN increases the production of various... -
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- Requirements for in vitro growth of human thymocytes
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Park SH, Bae YM, Park WS, Kim TJ, Chung DH, Song HG, Cho BJ, Kim CW, Lee SK
- KMID: 1421859
- J Korean Med Sci.
- 1991 Sep;6(3):224-233.
- doi: 10.3346/jkms.1991.6.3.224
Since it is difficult to study human thymocyte maturation in vitro, we have developed an in vitro thymocyte culture system which has allowed us to select the optimal growth conditions... -
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- Interleukin-8 production and interleukin-8 mRNA expression induced by lipopolysaccharides from Prevotella intermedia and Prevotella nigrescens in monocyte-derived macrophages
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Kim SJ
- KMID: 1733735
- J Korean Acad Periodontol.
- 2009 Jun;39(2):177-184.
- doi: 10.5051/jkape.2009.39.2.177
PURPOSE: Interleukin-8 (IL-8) is an important mediator of immune and inflammatory reactions and is produced by a variety of different cell types. This study was undertaken to investigate the effects... -
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- Phosphorylation of ribosomal protein S6 and its regulation during differentiation of human leukemic cells
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Kim IS, Lee SB, Cho KC
- KMID: 1422012
- J Korean Med Sci.
- 1993 Dec;8(6):413-419.
- doi: 10.3346/jkms.1993.8.6.413
We attempted to study the role of protein tyrosine kinase (PTK) and protein kinase C (PKC) in the cascade of phosphorylation of ribosomal protein S6 during differentiation of leukemic cells... -
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- Interaction of HIV-1 core p24 antigen with human monocytic cell line THP1 results in TNF-alpha dependent secretion of matrix metalloproteinase-9
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Sung JH, Yoo SH, Park HK, Chong YH
- KMID: 2001249
- J Korean Soc Microbiol.
- 2000 Feb;35(1):9-18.
Immunological mechanisms involving the release of inflammatory factors by HIV-1 infected microglia in the brain have been implicated in the pathogenesis of HIV dementia (HIVD). Since the regulation of matrix metalloproteinases (MMPs) activity... -
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- Expressional Regulation of Cancer Metastasis Related Gene, MMP-9, by Resveratrol
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Woo JH, Kim YH, Baek WK, Suh SI, Suh MH, Park JW, Kwon TK
- KMID: 1615505
- J Bacteriol Virol.
- 2003 Sep;33(3):235-243.
Proteolytic degradation of the extracellular matrix and tumor metastasis correlate with the expression of endopeptidases known as matrix metalloproteinases (MMPs). Expression of MMPs is regulated by cytokines and signal transduction... -
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- Inhibition of Interleukin-1 Signal by Annexin-1 in Phorbol Myristate Acetate Stimulated Lymphocytes
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Rhee HJ, Park KK, Na DS, Kim HW
- KMID: 1550785
- Korean J Immunol.
- 1999 Jun;21(2):147-152.
Annexin-1 (ANX1) is a 37 kDa protein that is induced and secreted by glucocorticosteroid hormone. The secreted ANX1 has been believed to exert its function by binding to its putative... -
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- Changes of Telomerase Activity by Protein Kinase C Modulators in Human Ovarian Cancer Cell Lines
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Hur SY, Lee JM, Namkoong S, Kim JW
- KMID: 2007089
- J Korean Cancer Assoc.
- 2000 Aug;32(4):724-733.
PURPOSE: This study was designed to find out whether protein kinase C (PKC) may affect telomerase activity in human ovarian cancers. MATERIALS AND METHODS: To determine whether PKC modulators influence PKC... -
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- A New Endothelial Molecule Involved in Melanoma Cell Binding to Human Dermal Microvascular Endothelial Cells
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Lee KH, Chung KY, Lawley TJ, Swerlick R
- KMID: 2361474
- Ann Dermatol.
- 1994 Jan;6(1):9-16.
- doi: 10.5021/ad.1994.6.1.9
BACKGROUND: We have previously demonstrated that phorbol myristate acetate (PMA)-induced increases in melanoma cell binding to endothelial cells derived from human dermis (HDMEC) are not mediated via known cell adhesion... -
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- Enhancement of Human Monocyte Activities against Aspergillus fumigatus by Interleukin-15
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Cho JH, Chang KH, Kim HY, Song YG, Kim CO, Park YS, Hong SK, Huh A, Yeon JS, Kim JM
- KMID: 2307091
- Korean J Med Mycol.
- 2001 Jun;6(2):64-69.
BACKGROUND: Despite recent advances in antifungal chemotherapy, invasive aspergillosis remains an important cause of morbidity and mortality in immunocompromised patients. Interleukin-15 (IL-15) is a cytokine that is known to enhance... -
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- Leptin potentiates Prevotella intermedia lipopolysaccharide-induced production of TNF-alpha in monocyte-derived macrophages
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Kim SJ
- KMID: 2212138
- J Periodontal Implant Sci.
- 2010 Jun;40(3):119-124.
- doi: 10.5051/jpis.2010.40.3.119
PURPOSE: In addition to regulating body weight, leptin is also recognized for its role in the regulation of immune function and inflammation. The purpose of this study was to investigate... -
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- Regulation of fibronectin gene expression by cyclic AMP and phorbol myristate acetate in HT-1080 human fibrosarcoma cells
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Lee BH, Park RW, Kim IS
- KMID: 755015
- Exp Mol Med.
- 1998 Dec;30(4):240-245.
We studied the regulation of fibronectin (FN) gene expression by cAMP and phorbol-12-myristate-13-acetate (PMA) in HT-1080 human fibrosarcoma cells. Dibutyryl cAMP increased FN synthesis and mRNA levels, while PMA inhibited... -
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- The Effect of Doxycycline on PMA-Induced MUC5B Expression via MMP-9 and p38 in NCI-H292 Cells
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Bae CH, Chen SM, Lee HM, Song SY, Kim YD
- KMID: 2166398
- Clin Exp Otorhinolaryngol.
- 2011 Dec;4(4):177-183.
OBJECTIVES: Doxycycline is commonly used in medicine for its bacteriostatic antimicrobial properties. Recent studies have reported that doxycycline also has anti-inflammatory effects. Matrix metalloproteinase (MMP)-9 has been found to be... -
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- Decreased Hydrogen Peroxide Generation by Neutrophils from Acne Patients Treated with Isotretinoin
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Kim WH, Park EJ, Park MW, Cho HS, Kim HJ, Kim CW, Cho HJ, Kim KH, Kim KJ, Kang KR
- KMID: 1881993
- Ann Dermatol.
- 2006 Oct;18(2):59-63.
- doi: 10.5021/ad.2006.18.2.59
Background: Reactive oxygen species (ROS) generated by neutrophils are closely correlated with the pathogenesis of a variety of inflammatory skin diseases. The aim of this study was to investigate whether... -
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- Expression of neurotensin/neuromedin N precursor in murine mast cells
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Ahn HJ, Cho JJ
- KMID: 1607138
- Korean J Physiol Pharmacol.
- 2001 Dec;5(6):495-501.
We have cloned the mouse neurotensin/neuromedin N (NT/N) gene from the murine mast cell line C1.MC/C57.1 for the first time. The murine NT/N cDNA clone consisted of 765 nucleotides and... -
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- Chemokine Lkn-1/CCL15 enhances matrix metalloproteinase-9 release from human macrophages and macrophage-derived foam cells
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Kwon SH, Ju SA, Kang JH, Kim CS, Yoo HM, Yu R
- KMID: 2313362
- Nutr Res Pract.
- 2008 Jun;2(2):134-137.
Atherosclerosis is characterized by a chronic inflammatory disease, and chemokines play an important role in both initiation and progression of atherosclerosis development. Leukotactin-1 (Lkn-1/CCL15), a new member of the human... -
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- The Regulation of Procalcitonin Production in Human Peripheral Blood Mononuclear Cells
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Choi HJ, Cho MS, Lee YJ
- KMID: 2285077
- Infect Chemother.
- 2006 Feb;38(1):11-16.
BACKGROUND: Procalcitonin (PCT) is a new marker of severe systemic bacterial infection. PCT consists of fragments katacalcin and calcitonin, which are precursors of calcitonin in thyroid. The source and role... -
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- Increased PMA-stimulated Release of MMP-9 and TGF-beta1 in the Plasma of Children with Persistent Asthma
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- KMID: 2299667
- Korean J Asthma Allergy Clin Immunol.
- 2005 Sep;25(3):200-204.
BACKGROUND: The contribution of matrix metalloproteinase (MMP)-9 to the pathogenesis of asthma has been reported. Transforming growth factor (TGF)-beta1 and interleukin (IL)- 11, and -17 are profibrotic cytokines which increase... -
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- Study on the Production and Function of Macrophage Migration Inhibitory Factor ( MIF ) : Effect of Recombinant MIF and MIF cDNA on the Induction of Cytokine mRNA
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Park JW, Suh MH, Suh SI, Baek WK, Han IS, Choe BK, Ahn SY, Yoon SJ, Shin SW, Bae JH
- KMID: 2083007
- Korean J Immunol.
- 1997 Sep;19(3):407-419.
In order to study the functions of migration inhibitory factor (MIF) as macrophage activating cytokine and to investigate the possibility of MIF cDNA as gene therapeutic agent or adjuvant, we... -
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