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Arginase-1 and P-glycoprotein are downregulated in canine hepatocellular carcinoma

Kim SH, Seung BJ, Cho SH, Lim HY, Bae MK, Sur JH

Background Hepatocellular carcinoma is the most common primary hepatic malignancy in humans and dogs. Several differentially expressed molecules have been studied and reported in human hepatocellular carcinoma and non-neoplastic liver lesions....
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How far can African swine fever spread?

Sur JH

African Swine Fever (ASF) is a highly contagious and deadly viral disease affecting both domestic pig and wild boar populations. Once introduced, it is a terrible disease that can devastate...
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Classification, bacteriological findings, and analysis of sex hormone receptors and cytokine expression in mammary lesions of abattoir sows

Ju JH, Shin JI, Lim HY, Kim HW, Seung BJ, Cho SH, Kim SH, Sur JH

Mammary lesions in sows can prevent suckling piglets from consuming colostrum that provides fundamental nutrients and protective immunity. Although mammary gross lesions are frequently found in sows at farms or...
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Differential and correlated expressions of p16/p21/p27/p38 in mammary gland tumors of aged dogs

Kim HW, Ju JH, Shin JI, Seung BJ, Sur JH

The inhibitory effect of neutering on mammary gland tumor development in dogs has been well described. However, we observed that the effect of neutering on tumor malignancy may be altered...
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A study of experimental autoimmune encephalomyelitis in dogs as a disease model for canine necrotizing encephalitis

Moon JH, Jung HW, Lee HC, Jeon JH, Kim NH, Sur JH, Ha J, Jung DI

In the present study, the use of dogs with experimental autoimmune encephalomyelitis (EAE) as a disease model for necrotizing encephalitis (NE) was assessed. Twelve healthy dogs were included in this...
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Canine model of ischemic stroke with permanent middle cerebral artery occlusion: clinical features, magnetic resonance imaging, histopathology, and immunohistochemistry

Jeon JH, Jung HW, Jang HM, Moon JH, Park KT, Lee HC, Lim HY, Sur JH, Kang BT, Ha J, Jung DI

The purpose of this study was to identify time-related changes in clinical, MRI, histopathologic, and immunohistochemical findings associated with ischemic stroke in dogs. Additionally, the association of cerebrospinal fluid (CSF)...
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Canine model of ischemic stroke with autologous thrombus in three dogs; Magnetic resonance imaging features and histopathological findings

Jeon JH, Jung HW, Lee HC, Kang BT, Sur JH, Jung DI

Ischemic stroke is the most common type of stroke in humans. The purpose of this study was to evaluate the diagnostic value of magnetic resonance imaging (MRI) in a canine...
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Minocycline as a treatment of dog with calcinosis cutis

Jang HJ, Kang MH, Sur JH, Park HM

  • KMID: 1790573
  • Korean J Vet Res.
  • 2013 Dec;53(4):253-256.
An 8-year-old, castrated male, Schnauzer dog was presented for evaluation of gradually worsening erythematous papules. Physical examination revealed multiple erythematous papules having a firm, gritty texture located in bilateral ears,...
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Juvenile cellulitis in a 7-month-old Shih-Tzu dog

Kang BT, Yi JH, Sur JH, Jung DI, Kang JH, Chang DW, Yang MP

  • KMID: 2055106
  • J Biomed Res.
  • 2013 Sep;14(3):180-183.
A-7-month-old, intact male Shih-Tzu dog was referred with facial dermatitis and stifle pain with 7 days duration. Erythema, hemorrhage, and crusted nodular lesions of the face, swollen eyelids, and otitis...
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Serial Expression of Hypoxia Inducible Factor-1alpha and Neuronal Apoptosis in Hippocampus of Rats with Chronic Ischemic Brain

Yu CH, Moon CT, Sur JH, Chun YI, Choi WH, Yhee JY

OBJECTIVE: The purpose of this study is to investigate serial changes of hypoxia-inducible factor 1alpha (HIF-1alpha), as a key regulator of hypoxic ischemia, and apoptosis of hippocampus induced by bilateral...
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Pro- and anti-inflammatory cytokine expression and histopathological characteristics in canine brain with traumatic brain injury

Yu CH, Yhee JY, Kim JH, Im KS, Kim NH, Jung DI, Lee HC, Chon SK, Sur JH

We analyzed the expression level and cellular localization of pro- and anti-inflammatory cytokines and histopathologically characterized canine traumatic brain injury (TBI). Canine TBI brains revealed subarachnoid and cerebral cortical hemorrhage,...
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Histopathological retrospective study of canine renal disease in Korea, 2003~2008

Yhee JY, Yu CH, Kim JH, Im KS, Chon SK, Sur JH

Renal disease includes conditions affecting the glomeruli, tubules, interstitium, pelvis, and vasculature. Diseases of the kidney include glomerular diseases, diseases of the tubules and interstitium, diseases of renal pelvis, and...
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Distribution and characterization of IL-10-secreting cells in lymphoid tissues of PCV2-infected pigs

Doster AR, Subramaniam S, Yhee JY, Kwon BJ, Yu CH, Kwon SY, Osorio FA, Sur JH

Distribution and characterization of interlukin-10 (IL-10)-secreting cells in lymphoid tissues of pigs naturally infected with porcine circovirus type 2 (PCV2) were evaluated in accordance with PCV2 antigen detection. After screening...
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Characterization of canine oral papillomavirus by histopathological and genetic analysis in Korea

Yhee JY, Kwon BJ, Kim JH, Yu CH, Im KS, Lee SS, Lyoo YS, Chang BJ, Sur JH

In August 2008, forty dogs out of 400 developed oral warts in a breeding farm in Korea. Canine oral papilloma infection is a common disease in dogs. However, there has...
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Comparative immunohistochemical characterization of canine seminomas and Sertoli cell tumors

Yu CH, Hwang DN, Yhee JY, Kim JH, Im KS, Nho WG, Lyoo YS, Sur JH

Primary testicular tumors are the most common causes of cancer in male dogs. Overall, the majority of canine patients should be cured by testicular surgery. However, tumor markers are not...
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