- The Role of Superantigen in Nasal Polypogenesis
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Yoon BK, Kim DW
- KMID: 2132085
- J Rhinol.
- 2013 Nov;20(2):88-95.
Superantigens are potent immunostimulatory exotoxins well known to be produced by Staphylococcus aureus (S. aureus). These exotoxins have capacity to act as superantigens by binding with the variable beta(Vbeta) region... -
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- Role of Fungal and Bacterial Superantigen in the Pathogenesis of Chronic Rhinosinusitis with Polyps
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Shin SH
- KMID: 2131931
- J Rhinol.
- 2008 Nov;15(2):98-102.
Chronic rhinosinusitis (CRS) is an inflammatory disorder with numerous predisposing factors, including genetics, anatomic anomalies, bacteria, and fungus. CRS with nasal polyps can be distinguished by an eosinophilic type inflammation... -
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- Serum Specific IgE to Staphylococcal Superantigens in Sera of ASA-intolerant Asthma
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- KMID: 2090094
- Korean J Asthma Allergy Clin Immunol.
- 2004 Jun;24(2):247-252.
OBJECTIVE: Several studies suggest that serum total IgE (tIgE) level tended to be higher in ASA-intolerant asthma (AIA) than in other types of non-atopic asthma, whether they are atopics or... -
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- Advances In the Pathophysiology of Atopic Dermatitis
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Park YM
- KMID: 2051627
- Pediatr Allergy Respir Dis.
- 2006 Sep;16(3):189-196.
Atopic dermatitis is a common chronic inflammatory skin disease often preceding the development of asthma and allergic disorders, such as food allergy or allergic rhinoconjunctivitis. The incidence of atopic dermatitis... -
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- Association of Specific IgE to Staphylococcal Superantigens with the Phenotype of Chronic Urticaria
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Ye YM, Hur GY, Park HJ, Kim SH, Kim HM, Park HS
- KMID: 1783071
- J Korean Med Sci.
- 2008 Oct;23(5):845-851.
- doi: 10.3346/jkms.2008.23.5.845
It has been well established that bacterial superantigens lead to the induction and aggravation of chronic inflammatory skin diseases. We investigated the clinical significance of serum specific immunoglobulin E (lgE)... -
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- Immunologic Role of Fungi in the Pathophysiology of Chronic Rhinosinusitis
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Shin SH
- KMID: 2132084
- J Rhinol.
- 2013 Nov;20(2):82-87.
Chronic rhinosinusitis (CRS) is a very common condition but it's pathogenesis is not completely understood. Although, fungi have been suggested to play an important role in the pathogenesis of CRS,... -
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- The Innate Immune Responses in Pathogenesis of Chronic Rhinosinusitis
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Mo JH
- KMID: 2146667
- J Rhinol.
- 2014 May;21(1):22-27.
- doi: 10.0000/jr.2014.21.1.22
Chronic rhinosinusitis (CRS) is a multifactorial and heterogeneous disease, and variousfactors, such as inflammation, infection, fungus, and superantigens, have been proposed to play crucial roles in its pathogenesis. Recently, the... -
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- Response of Peripheral Blood Mononuclear Cells to Staphylococcus Aureus Exotoxin in Nasal Polyposis
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Hwang SH, Kim BG, Kim SW, Cho JH, Shin JH, Kang JM
- KMID: 2131999
- J Rhinol.
- 2010 Nov;17(2):92-96.
BACKGROUND AND OBJECTIVES: Superantigens such as Staphylococcus aureus exotoxin (SE) have been implicated in the pathogenesis of chronic rhinosinusitis with nasal polyposis (NP). The aim of this study was to... -
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- IL-5 Promoter Polymorphism Enhances IgE Responses to Staphylococcal Superantigens in Adult Asthmatics
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Losol P, Kim SH, Hwang EK, Shin YS, Park HS
- KMID: 2260346
- Allergy Asthma Immunol Res.
- 2013 Mar;5(2):106-109.
- doi: 10.4168/aair.2013.5.2.106
Interleukin 5 (IL-5) is a key cytokine involved in the induction of T-helper type 2 (Th2) responses in the asthmatic airway. We investigated IL-5 genetic polymorphisms associated with asthma phenotypes,... -
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- The Prevalence of Serum Specific IgE to Superantigens in Asthma and Allergic Rhinitis Patients
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Liu JN, Shin YS, Yoo HS, Nam YH, Jin HJ, Ye YM, Nahm DH, Park HS
- KMID: 2260690
- Allergy Asthma Immunol Res.
- 2014 May;6(3):263-266.
- doi: 10.4168/aair.2014.6.3.263
Staphylococcus aureus is the most common bacterium present in upper respiratory tract, and the toxins it produced are involved in allergic inflammation pathogenesis. In this study, we investigated the clinical... -
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- Development and Utilization of a Mouse Model of Nasal Polyps
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Kim SW, Jeon SY, Kim DW
- KMID: 2297547
- J Rhinol.
- 2015 May;22(1):1-5.
- doi: 10.18787/jr.2015.22.1.1
Systemic corticosteroids currently represent the most effective treatment for chronic rhinosinusitis with nasal polyps (CRSwNP), but their long-term use is constrained due to their detrimental side effects. Until recently, development... -
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- Superantigen and class II MHC molecules
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Kim J
- KMID: 927169
- J Korean Med Sci.
- 1995 Dec;10(6):393-398.
- doi: 10.3346/jkms.1995.10.6.393
No anstract available. -
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- Role of Staphylococcal Superantigen in Atopic Dermatitis: Influence on Keratinocytes
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Kim KH, Han JH, Chung JH, Cho KH, Eun HC
- KMID: 1781842
- J Korean Med Sci.
- 2006 Apr;21(2):315-323.
- doi: 10.3346/jkms.2006.21.2.315
Staphylococcus aureus may perform an crucial function in atopic dermatitis (AD), via the secretion of superantigens, including staphylococcal enterotoxins (SE) A or B, and toxic shock syndrome toxin-1 (TSST-1). Dysregulated... -
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- Association Between PTPN22 Polymorphisms and IgE Responses to Staphylococcal Superantigens in Chronic Urticaria
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Palikhe S, Kim SH, Pham LD, Ye YM, Park HS
- KMID: 2260467
- Allergy Asthma Immunol Res.
- 2015 May;7(3):290-294.
- doi: 10.4168/aair.2015.7.3.290
Protein tyrosine phosphatase-22 (PTPN22) gene encodes lymphoid-specific tyrosine phosphatase (Lyp), an inhibitor of T cell activation. A polymorphism of the PTPN22 gene has been found to be associated with chronic... -
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- The Effects of Staphylococci on the Degranulation of Human Mast Cell-1
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Jang IT, Yang M, Jo EK, Kim HJ, Park JK
- KMID: 2392961
- J Bacteriol Virol.
- 2017 Sep;47(3):132-138.
- doi: 10.4167/jbv.2017.47.3.132
Atopic dermatitis (AD) is characterized by disturbances in epidermal barrier functions and the hyperactive immune response. Staphylococcus aureus (S. aureus) can be cultured from 90% of AD skin lesions and... -
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- Expression of Toll-like Receptors on the Macrophages Activated by Bacterial Superantigens
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Kim HY, Cho HC, Kim SK, Shin KC
- KMID: 2285109
- Infect Chemother.
- 2004 Oct;36(5):286-293.
BACKGROUND: Staphylococcal enterotoxin B (SEB) as a prototype superantigen is known to play a pivotal role in toxic shock syndrome and severe sepsis. However, the precise mechanism initiating the activation... -
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- Interactions Between Atopic Dermatitis and Staphylococcus aureus Infection: Clinical Implications
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Kim J, Kim BE, Ahn K, Leung DY
- KMID: 2452751
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):593-603.
- doi: 10.4168/aair.2019.11.5.593
Staphylococcus aureus commonly colonizes the skin of atopic dermatitis (AD) patients and contributes to the development and exacerbation of AD. Multiple factors are associated with colonization of AD skin by... -
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- Bacterial Ball as an Unusual Finding in Patients With Chronic Rhinosinusitis
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Kim DK, Wi YC, Shin SJ, Jang YI, Kim KR, Cho SH
- KMID: 2407791
- Clin Exp Otorhinolaryngol.
- 2018 Mar;11(1):40-45.
- doi: 10.21053/ceo.2017.00332
OBJECTIVES: Pathophysiology of chronic rhinosinusitis (CRS) is very complex and has not yet been clearly understood. To date, various factors have been researched to have relations with the pathogenesis of... -
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- A Comparison Study of the Staphylococcal Exotoxins and Staphylococcal Enterotoxin A-specific IgE Antibody between Childhood and Adulthood Atopic Dermatitis
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Kim HW, Park CW, Lee CH, Song WK
- KMID: 2362393
- Ann Dermatol.
- 2003 Sep;15(3):99-100.
- doi: 10.5021/ad.2003.15.3.99
BACKGROUND: The skin of patients with atopic dermatitis (AD) exhibits a striking susceptibility to colonization with Staphylococcus aureus (S. aureus). Superantigens produced by S. aureus and their specific IgE antibodies... -
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- Analysis of Colonization and Genotyping of the Exotoxins of Staphylococcus aureus in Patients with Atopic Dermatitis
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Na SY, Roh JY, Kim JM, Tamang MD, Lee JR
- KMID: 2266035
- Ann Dermatol.
- 2012 Nov;24(4):413-419.
- doi: 10.5021/ad.2012.24.4.413
BACKGROUND: The skin of atopic dermatitis (AD) patients has a high susceptibility to Staphylococcus aureus colonization, and the toxins produced by S. aureus may aggravate AD by acting as superantigens. OBJECTIVE:... -
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