- Successful sulfonylurea treatment in a patient with permanent neonatal diabetes mellitus with a novel KCNJ11 mutation
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Ahn SY, Kim GH, Yoo HW
- KMID: 2284606
- Korean J Pediatr.
- 2015 Aug;58(8):309-312.
- doi: 10.3345/kjp.2015.58.8.309
Permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and persists through life. It is a rare disorder affecting one in 0.2-0.5 million live... -
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- Effects of Sulfonylureas on Peroxisome Proliferator-Activated Receptor gamma Activity and on Glucose Uptake by Thiazolidinediones
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Lee KW, Ku YH, Kim M, Ahn BY, Chung SS, Park KS
- KMID: 2281640
- Diabetes Metab J.
- 2011 Aug;35(4):340-347.
- doi: 10.4093/dmj.2011.35.4.340
BACKGROUND: Sulfonylurea primarily stimulates insulin secretion by binding to its receptor on the pancreatic beta-cells. Recent studies have suggested that sulfonylureas induce insulin sensitivity through peroxisome proliferator-activated receptor gamma (PPARgamma),... -
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- Concurrent Use of Sulfonylureas and Antimicrobials of the Elderly in Korea: A Potential Risk of Hypoglycemia
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Lee S, Ock M, Kim H
- KMID: 2438544
- Korean J Clin Pharm.
- 2018 Sep;28(3):188-193.
- doi: 10.24304/kjcp.2018.28.3.188
BACKGROUND: Previous studies have noted that the simultaneous use of sulfonylureas and antimicrobials, which is common, could increase the risk of hypoglycemia. In particular, an age of 65 years or... -
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- Ameliorating Effects of Sulfonylurea Drugs on Insulin Resistance in Otsuka Long-Evans Tokushima Fatty Rats
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Park JK, Kim SP, Song DK
- KMID: 2071640
- Korean J Physiol Pharmacol.
- 2008 Feb;12(1):7-12.
- doi: 10.4196/kjpp.2008.12.1.7
OLETF (Otsuka Long-Evans Tokushima Fatty) rats are characterized by obesity-related insulin resistance, which is a phenotype of type 2 diabetes. Sulfonylurea drugs or benzoic acid derivatives as inhibitors of the... -
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- Additional Effect of Dietary Fiber in Patients with Type 2 Diabetes Mellitus Using Metformin and Sulfonylurea: An Open-Label, Pilot Trial
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Lee SE, Choi Y, Jun JE, Lee YB, Jin SM, Hur KY, Ko GP, Lee MK
- KMID: 2455666
- Diabetes Metab J.
- 2019 Aug;43(4):422-431.
- doi: 10.4093/dmj.2018.0090
BACKGROUND: Metformin, sulfonylurea, and dietary fiber are known to affect gut microbiota in patients with type 2 diabetes mellitus (T2DM). This open and single-arm pilot trial investigated the effects of... -
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- Clinical Characteristics and Metabolic Predictors of Rapid Responders to Dipeptidyl Peptidase-4 Inhibitor as an Add-on Therapy to Sulfonylurea and Metformin
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Kim YA, Yoo WS, Hong ES, Ku EJ, Park KS, Lim S, Cho YM, Park KS, Jang HC, Choi SH
- KMID: 2174001
- Diabetes Metab J.
- 2015 Dec;39(6):489-497.
- doi: 10.4093/dmj.2015.39.6.489
BACKGROUND: Dipeptidyl peptidase-4 (DPP-4) inhibitor add-on therapy is a new option for patients with inadequately controlled type 2 diabetes who are taking combined metformin and sulfonylurea (SU). We evaluated the... -
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- Sulfonylurea Therapy in Two Korean Patients with Insulin-treated Neonatal Diabetes due to Heterozygous Mutations of the KCNJ11 Gene Encoding Kir6.2
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Kim MS, Kim SY, Kim GH, Yoo HW, Lee DW, Lee DY
- KMID: 1127075
- J Korean Med Sci.
- 2007 Aug;22(4):616-620.
- doi: 10.3346/jkms.2007.22.4.616
Permanent neonatal diabetes (PND) is a rare form of diabetes characterized by insulin-requiring hyperglycemia diagnosed within the first three months of life. In most cases, the causes are not known.... -
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- Chronic Hepatitis C and Insulin Resistance
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Chung WJ
- KMID: 1364829
- Korean J Gastroenterol.
- 2012 Apr;59(4):268-274.
- doi: 10.4166/kjg.2012.59.4.268
Insulin resistance is frequently associated with chronic liver disease, and the interaction between hepatitis C virus (HCV) infection and insulin resistance is a major public health issue, bound to increase... -
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- Increasing Trend in the Number of Severe Hypoglycemia Patients in Korea
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Kim JT, Oh TJ, Lee YA, Bae JH, Kim HJ, Jung HS, Cho YM, Park KS, Lim S, Jang HC, Lee HK
- KMID: 2281715
- Diabetes Metab J.
- 2011 Apr;35(2):166-172.
- doi: 10.4093/dmj.2011.35.2.166
BACKGROUND: To investigate whether the number of subjects with severe hypoglycemia who are brought to a hospital emergency department is increasing and to identify whether there have been changes in... -
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- A Case of Term Delivery with Diagnosis of Severe Oligohydramnios after Exposure to Glimepiride, Metformin and Antihypertensive agents Including Angiotensin Receptor Antagonist up to Approximately 20 Weeks of Pregnancy
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Kwak DW, Yoo IS, Choi JS
- KMID: 2280926
- Korean J Perinatol.
- 2013 Jun;24(2):95-100.
- doi: 10.14734/kjp.2013.24.2.95
Various fetal and maternal conditions are known to be associated with oligohydramnios. In general, oligohydramnios developed early in pregnancy is less common but frequently has a poor prognosis. The use... -
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- Comparison of Vildagliptin-Metformin and Glimepiride-Metformin Treatments in Type 2 Diabetic Patients
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Jeon HJ, Oh TK
- KMID: 1857509
- Diabetes Metab J.
- 2011 Oct;35(5):529-535.
- doi: 10.4093/dmj.2011.35.5.529
BACKGROUND: The present study investigated the efficacy and safety of vildagliptin-metformin treatment compared to those of glimepiride-metformin treatment for type 2 diabetes. METHODS: In a randomized, open-label, comparative study, 106 patients... -
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- Clinical Course in Patients with an Intentional Amlodipine Overdose
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Jeon YW, Kim JY, Park JS, Park JM, Gil HW, Yang JO, Lee EY, Hong SY
- KMID: 2263790
- Korean J Med.
- 2011 Aug;81(2):208-214.
BACKGROUND/AIMS: Calcium channel blockers (CCBs) are anti-hypertensive medications that are used worldwide. CCB overdose has increased in proportion to the use of these drugs. Although amlodipine is the most widely... -
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- Efficacy of Sitagliptin When Added to Ongoing Therapy in Korean Subjects with Type 2 Diabetes Mellitus
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Chung HS, Lee MK
- KMID: 2281649
- Diabetes Metab J.
- 2011 Aug;35(4):411-417.
- doi: 10.4093/dmj.2011.35.4.411
BACKGROUND: To evaluate the clinical efficacy of sitagliptin for reducing plasma glucose levels in Korean subjects with type 2 diabetes mellitus during a 14-week treatment period. METHODS: Our study design involved... -
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- DPP-4 Inhibitors and the Relations between Rosiglitazone and the Risk of Myocardial Infarction
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Lee HW
- KMID: 2185748
- J Korean Med Assoc.
- 2008 Apr;51(4):371-376.
- doi: 10.5124/jkma.2008.51.4.371
If the type 2 diabetes is left untreated, it can eventually be lead to vascular complications, including nephropathy, retinopathy, neuropathy, coronary heart disease, and CVA. The current antidiabetic drugs are... -
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- Efficacy and Safety of Pioglitazone versus Glimepiride after Metformin and Alogliptin Combination Therapy: A Randomized, Open-Label, Multicenter, Parallel-Controlled Study
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Kim JM, Kim SS, Kim JH, Kim MK, Kim TN, Lee SH, Lee CW, Park JY, Kim ES, Lee KJ, Choi YS, Kim DK, Kim IJ
- KMID: 2470956
- Diabetes Metab J.
- 2020 Feb;44(1):67-77.
- doi: 10.4093/dmj.2018.0274
BACKGROUND: There is limited information regarding the optimal third-line therapy for managing type 2 diabetes mellitus (T2DM) that is inadequately controlled using dual combination therapy. This study assessed the efficacy... -
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- Glycemic Effects of Once-a-Day Rapid-Acting Insulin Analogue Addition on a Basal Insulin Analogue in Korean Subjects with Poorly Controlled Type 2 Diabetes Mellitus
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Choe EY, Lee YH, Lee BW, Kang ES, Cha BS, Lee HC
- KMID: 2281404
- Diabetes Metab J.
- 2012 Jun;36(3):230-236.
- doi: 10.4093/dmj.2012.36.3.230
BACKGROUND: The present study investigates the efficacy in glycemic control by adding once-a-day glulisine to glargine as a basal plus regimen and factors influencing glycemic control with the basal plus... -
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- Comparison of the Efficacy of Glimepiride, Metformin, and Rosiglitazone Monotherapy in Korean Drug-Naive Type 2 Diabetic Patients: The Practical Evidence of Antidiabetic Monotherapy Study
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Yoon KH, Shin JA, Kwon HS, Lee SH, Min KW, Ahn YB, Yoo SJ, Ahn KJ, Park SW, Lee KW, Sung YA, Park TS, Kim MS, Kim YK, Nam MS, Kim HS, Park IB, Park JS, Woo JT, Son HY
- KMID: 2281489
- Diabetes Metab J.
- 2011 Feb;35(1):26-33.
- doi: 10.4093/dmj.2011.35.1.26
BACKGROUND: Although many anti-diabetic drugs have been used to control hyperglycemia for decades, the efficacy of commonly-used oral glucose-lowering agents in Korean type 2 diabetic patients has yet to be... -
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- Serum Insulin, Proinsulin and Proinsulin/Insulin Ratio in Type 2 Diabetic Patients: As an Index of beta-Cell Function or Insulin Resistance
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Kim NH, Kim DL, Choi KM, Baik SH, Choi DS
- KMID: 759518
- Korean J Intern Med.
- 2000 Dec;15(3):195-201.
BACKGROUND: Although insulin resistance and decreased insulin secretion are characteristics of established type 2 DM, which of these metabolic abnormalities is the primary determinant of type 2 DM is controversial.... -
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