- Stem Cell Properties of Therapeutic Potential
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Seo GS
- KMID: 1018399
- Korean J Gastroenterol.
- 2011 Sep;58(3):125-132.
- doi: 10.4166/kjg.2011.58.3.125
Stem cell research is a innovative technology that focuses on using undifferentiated cells able to self-renew through the asymmetrical or symmetrical divisions. Three types of stem cells have been studied... -
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- Clinical application of stem cells in liver diseases
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Bae SH
- KMID: 1381461
- Korean J Hepatol.
- 2008 Sep;14(3):309-317.
- doi: 10.3350/kjhep.2008.14.3.309
Most liver diseases lead to hepatic dysfunction with organ failure. Liver transplantation is the best curative therapy, but it has some limitations such as donor shortage, possibility of rejection, and... -
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- Clinical Trials with Stem Cells in Digestive Diseases and Future Perspectives
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Kim TI
- KMID: 1018401
- Korean J Gastroenterol.
- 2011 Sep;58(3):139-143.
- doi: 10.4166/kjg.2011.58.3.139
Many techniques for isolation, expansion and handling of stem cells are being developed rapidly, and preclinical evidence has shown the possibility to use this technology for refractory diseases in the... -
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- Strategies for ensuring that regenerative cardiomyocytes function properly and in cooperation with the host myocardium
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Hattori F, Fukuda K
- KMID: 946648
- Exp Mol Med.
- 2010 Mar;42(3):155-165.
- doi: 10.3858/emm.2010.42.3.022
In developed countries, in which people have nutrient-rich diets, convenient environments, and access to numerous medications, the disease paradigm has changed. Nowadays, heart failure is one of the major causes... -
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- Preclinical Experience in Stem Cell Therapy for Digestive Tract Diseases
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Jeon MS, Hong SS
- KMID: 1018400
- Korean J Gastroenterol.
- 2011 Sep;58(3):133-138.
- doi: 10.4166/kjg.2011.58.3.133
Adult stem cells are multipotent and self-renewing cells that contain several functions; i) migration and homing potential: stem cells can migrate to injured and inflamed tissues. ii) differentiation potential: stem... -
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- Very small embryonic-like stem-cell optimization of isolation protocols: an update of molecular signatures and a review of current in vivo applications
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Shin DM, Suszynska , Mierzejewska K, Ratajczak , Ratajczak
- KMID: 2154275
- Exp Mol Med.
- 2013 Nov;45(11):e56.
As the theory of stem cell plasticity was first proposed, we have explored an alternative hypothesis for this phenomenon: namely that adult bone marrow (BM) and umbilical cord blood (UCB)... -
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- MicroRNAs in Human Embryonic and Cancer Stem Cells
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Navarro A, Monzo M
- KMID: 1071411
- Yonsei Med J.
- 2010 Sep;51(5):622-632.
- doi: 10.3349/ymj.2010.51.5.622
MicroRNAs (miRNAs) are small non-coding RNAs that regulate messenger RNAs at the post-transcriptional level. They play an important role in the control of cell physiological functions, and their alterations have... -
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- Evaluation of Stem Cell Components in Retrocorneal Membranes
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Lee SH, Kim KW, Kim MK, Chun YS, Kim JC
- KMID: 1796949
- J Korean Med Sci.
- 2014 Jun;29(6):846-851.
- doi: 10.3346/jkms.2014.29.6.846
The purpose of this study was to elucidate the origin and cellular composition of retrocorneal membranes (RCMs) associated with chemical burns using immunohistochemical staining for primitive cell markers. Six cases... -
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- Developmental changes in hematopoietic stem cell properties
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Copley MR, Eaves CJ
- KMID: 2154274
- Exp Mol Med.
- 2013 Nov;45(11):e55.
Hematopoietic stem cells (HSCs) comprise a rare population of cells that can regenerate and maintain lifelong blood cell production. This functionality is achieved through their ability to undergo many divisions... -
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- Vascular differentiation of multipotent spermatogonial stem cells derived from neonatal mouse testis
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Im JE, Song SH, Kim JY, Kim KL, Baek SH, Lee DR, Suh W
- KMID: 1365907
- Exp Mol Med.
- 2012 Apr;44(4):303-309.
- doi: 10.3858/emm.2012.44.4.034
We previously reported the successful establishment of embryonic stem cell (ESC)-like multipotent spermatogonial stem cells (mSSCs) from neonatal mouse testis. Here, we examined the ability of mSSCs to differentiate into... -
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- Efficient culture system for human embryonic stem cells using autologous human embryonic stem cell-derived feeder cells
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Yoo SJ, Yoon BS, Kim JM, Song JM, Roh SI, You S, Yoon HS
- KMID: 1089449
- Exp Mol Med.
- 2005 Oct;37(5):399-407.
Human embryonic stem cells (hESCs) need feeder cells for their maintenance in an undifferentiated state. In conventional culture systems, mouse embryonic fibroblasts (MEFs) serve as feeder cells to maintain hESCs.... -
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- Understanding of molecular mechanisms in natural killer cell therapy
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Yoon SR, Kim TD, Choi I
- KMID: 2155406
- Exp Mol Med.
- 2015 Feb;47(2):e141.
- doi: 10.1038/emm.2014.114
Cancer cells and the immune system are closely related and thus influence each other. Although immune cells can suppress cancer cell growth, cancer cells can evade immune cell attack via... -
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- Tissue Engineering of Injectable Soft tissue Filler: Using Adipose Stem Cells and Micronized Acellular Dermal Matrix
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Yoo G, Lim JS
- KMID: 1794414
- J Korean Med Sci.
- 2009 Feb;24(1):104-109.
- doi: 10.3346/jkms.2009.24.1.104
In this study of a developed soft tissue filler, adipose tissue equivalents were constructed using adipose stem cells (ASCs) and micronized acellular dermal matrix (Alloderm). After labeling cultured human ASCs... -
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- Advanced Properties of Urine Derived Stem Cells Compared to Adipose Tissue Derived Stem Cells in Terms of Cell Proliferation, Immune Modulation and Multi Differentiation
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Kang HS, Choi SH, Kim BS, Choi JY, Park GB, Kwon TG, Chun SY
- KMID: 2359960
- J Korean Med Sci.
- 2015 Dec;30(12):1764-1776.
- doi: 10.3346/jkms.2015.30.12.1764
Adipose tissue stem cells (ADSCs) would be an attractive autologous cell source. However, ADSCs require invasive procedures, and has potential complications. Recently, urine stem cells (USCs) have been proposed as... -
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- Effect of Human Parathyroid Hormone on Hematopoietic Progenitor Cells in NOD/SCID Mice Co-Transplanted with Human Cord Blood Mononuclear Cells and Mesenchymal Stem Cells
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Lim YJ, Hwang K, Kim M, Cho YH, Lee JH, Lee YH, Seo JJ
- KMID: 1776945
- Yonsei Med J.
- 2013 Jan;54(1):238-245.
- doi: 10.3349/ymj.2013.54.1.238
PURPOSE: We evaluated the effect of human parathyroid hormone (hPTH) on the engraftment and/or in vivo expansion of hematopoietic stem cells in an umbilical cord blood (UCB)-xenotransplantation model. In addition,... -
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- Extensive characterization of feline intra-abdominal adipose-derived mesenchymal stem cells
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Kim HR, Lee J, Byeon JS, Gu NY, Lee J, Cho IS, Cha SH
- KMID: 2412447
- J Vet Sci.
- 2017 Sep;18(3):299-306.
- doi: 10.4142/jvs.2017.18.3.299
Mesenchymal stem cells (MSCs) isolated from various tissues have been well characterized for therapeutic application to clinical diseases. However, in contrast to MSCs from other animal species, the characteristics of... -
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- Overexpression of bone morphogenetic protein 4 in STO fibroblast feeder cells represses the proliferation of mouse embryonic stem cells in vitro
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Kim GH, Lee GR, Choi HI, Park NH, Chung HT, Han IS
- KMID: 1397450
- Exp Mol Med.
- 2012 Jul;44(7):457-463.
Embryonic stem cells (ESCs) can be propagated in vitro on feeder layers of mouse STO fibroblast cells. The STO cells secrete several cytokines that are essential for ESCs to maintain... -
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- CKbeta8-1 alters expression of cyclin E in colony forming units-granulocyte macrophage (CFU-GM) lineage from human cord blood CD34 + cells
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Noh EK, Ra JS, Lee SA, Kwon BS, Han IS
- KMID: 1116207
- Exp Mol Med.
- 2005 Dec;37(6):619-623.
A C6 beta-chemokine, CKbeta8-1, suppressed the colony formation of CD34 + cells of human cord blood (CB). Molecular mechanisms involved in CKbeta8-1-medicated suppression of colony formation of CD34 + cells... -
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- Hematologic Recovery after Tandem High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Children with High-Risk Solid Tumors
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Son MH, Kim DH, Lee SH, Yoo KH, Sung KW, Koo HH, Kim JY, Cho EJ, Kang ES, Kim DW
- KMID: 1429184
- J Korean Med Sci.
- 2013 Feb;28(2):220-226.
- doi: 10.3346/jkms.2013.28.2.220
Although the number of studies using tandem high-dose chemotherapy and autologous stem cell transplantation (HDCT/autoSCT) for the treatment of high-risk pediatric solid tumors has been increasing, documentation of hematologic recovery... -
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- Comparison of Cytokine Expression in Mesenchymal Stem Cells from Human Placenta, Cord Blood, and Bone Marrow
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Hwang JH, Shim SS, Seok OS, Lee HY, Woo SK, Kim BH, Song HR, Lee JK, Park YK
- KMID: 1779182
- J Korean Med Sci.
- 2009 Aug;24(4):547-554.
- doi: 10.3346/jkms.2009.24.4.547
Mesenchymal stem cells (MSCs) are capable of self-renewal and differentiation into lineages of mesenchymal tissues that are currently under investigation for a variety of therapeutic applications. The purpose of this... -
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