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An Electron Microscopic Observation on Germinal Epithelium of Infertile Men

Kim SC, Suh ST

  • KMID: 2036960
  • Korean J Urol.
  • 1974 Sep;15(3):211-218.
The changes in the germinal epithelium of 27 azoospermic patients were studied by light and electron microscope. And a brief clinical observation was also made. The results obtained were as...
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Morphology and Function of Testis in Growth Deprived Mature and Immature Male Rats

Choi HR, Lee SH, Lee MS, Lee JM

  • KMID: 2060492
  • Korean J Urol.
  • 1994 Apr;35(4):357-364.
Growth hormone(GH) plays a major role in growth and its effects are mainly mediated by insulin like growth factor-I ( IGF-I). However the role of GH in the regulation of...
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Functions of PIWI proteins in spermatogenesis

Bak CW, Yoon TK, Choi Y

Recently, a significant understanding of the molecular mechanisms regulating spermatogenesis has been achieved utilizing small RNA molecules (small RNAs), including small interfering RNAs (siRNAs), microRNAs (miRNAs), and Piwi-interacting RNAs (piRNAs)...
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Ultrastructure of the Rat Testes in Experimental Cryptorchidism

Koh SK

  • KMID: 1911590
  • Korean J Urol.
  • 1983 Aug;24(4):539-544.
Since 1786 by Hunter the cryptorchidism was described, many investigators observed the cryptorchism clinically and experimentally. Recently pediatric urologists have interest especially because it is high incidence as a congenital...
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Unilateral cryptorchidism induces morphological changes of testes and hyperplasia of Sertoli cells in a dog

Moon JH, Yoo DY, Jo YK, Kim GA, Jung HY, Choi JH, Hwang IK, Jang G

Cryptorchidism is one of the most common genital defects in dogs. This study investigated the effects of abdominal cryptorchidism on morphology, cell proliferation, and Sertoli cell condition in a dog...
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Long-Term Exposure of Rats to a 2.45 GHz Electromagnetic Field: Effects on Reproductive Function

Kim JY, Kim HT, Moon KH, Shin HJ

PURPOSE: We wanted to evaluate the effects of a 2.45 GHz electromagnetic field(EMF) radiation on germ cell spermatogenesis. MATERIALS AND METHODS: Twenty male Sprague-Dawley rats(4 weeks of age) were exposed to...
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Immunohistochemical localization of glucose transporter 1 and 3 in the scrotal and abdominal testes of a dog

Hahn KR, Jung HY, Yoo DY, Kim JW, Kim YH, Jo YK, Kim GA, Chung JY, Choi JH, Hwang IK, Jang G, Yoon YS

Glucose is essential for testicular function; the uptake of carbohydrate-derived glucose by cells is mediated by glucose transporters (GLUTs). In the present study, we investigated the activity of GLUT1 and...
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Differentiation of human male germ cells from Wharton's jelly-derived mesenchymal stem cells

Dissanayake D, Patel H, Wijesinghe P

OBJECTIVE: Recapitulation of the spermatogenesis process in vitro is a tool for studying the biology of germ cells, and may lead to promising therapeutic strategies in the future. In this...
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Properties of Extremely Low Frequency Electromagnetic Fields and their Effects on Mouse Testicular Germ Cells

Kim YS, Lee SK

  • KMID: 1457205
  • Int J Oral Biol.
  • 2010 Dec;35(4):137-144.
To evaluate the biohazard properties of an extremely low frequency electromagnetic field (ELF-EMF), we explored the physical properties of the ELF-EMF that generates the electric current induction in the secondary...
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Effects of Sesame Oil on the Reproductive Parameters of Diabetes Mellitus-Induced Male Rats

Abbasi Z, Tabatabaei SRF, Mazaheri Y, Barati F, Morovvati

  • KMID: 2320842
  • World J Mens Health.
  • 2013 Aug;31(2):141-149.
PURPOSE: The purpose of the present study was to investigate the effect of sesame oil on the reproductive parameters of diabetic male Wistar rats. MATERIALS AND METHODS: The adult male rats...
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Involvement of the Fas and Fas ligand in testicular germ cell apoptosis by zearalenone in rat

Jee Y, Noh EM, Cho ES, Son HY

Zearalenone (ZEA), a nonsteroidal estrogenic mycotoxin, is known to cause testicular toxicity in animals. In the present study, the effects of ZEA on spermatogenesis and possible mechanisms involved in germ...
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False Negative of Doppler Ultrasonography During Testis Torsion in Animal Model

Chang HJ, Oh YH, Kim DH, Sohn HG, Ha DB, Lee KS

  • KMID: 2289925
  • Korean J Urol.
  • 1999 Sep;40(9):1235-1240.
PURPOSE: Our aim is to identify the false negative rate of doppler ultrasonography and to compare color doppler ultrasonography with pathologic findings during testis torsion in animal model. MATERIALS AND METHODS:...
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Light and Electron Microscopic Observation in the Frozen-thawed Mouse Testicular Tissues

Han SC, Song SJ, Lee SH, Oh SH, Koong MK, Park YS

  • KMID: 1979048
  • Korean J Fertil Steril.
  • 2003 Jun;30(2):127-134.
OBJECTIVE: The aim of this study was to investigate the morphological aspects of testicular tissue before and after freezing-thawing by light and transmission electron microscopy. METHODS: Tissue biopsies were carried out...
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The Effects of Leuprolide Acetate to the Testicular Histopathology of Male Rat

Park TS, Kim DH

  • KMID: 1912687
  • Korean J Urol.
  • 1989 Oct;30(5):655-661.
We performed this study to observe the effects of chronic administration of leuprolide acetate(potent synthetic LHRH analog) to the testicular histopathology of prostatic cancer patient and to the spermatogenesis in...
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Ameliorative effect of vitamin B12 on seminiferous epithelium of cimetidine-treated rats: a histopathological, immunohistochemical and ultrastructural study

Elsaed WM, Bedeer RF, Eladl MA

Cimetidine is an H2 receptor antagonist that has an antiandrogenic effect. It intervenes with the conversion of testosterone into estrogen in the Sertoli cells with accompanying testicular structural changes. In...
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Pericentric Inversion of the X Chromosome in a Male with Azoospermia and in the Family of a Pregnant Female Carrier

Lee BY, Ryu HM, Lee MH, Park JY, Kim JW, Lee JS, Kim HO, Kim MH, Park SY

  • KMID: 2184460
  • J Genet Med.
  • 2008 Dec;5(2):139-144.
We report on two cases of pericentric inversion of X chromosome. The cases were found in a 40-year- old man with azoospermia and in a family of a 38-year-old pregnant...
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Potassium Depletion Upregulates Expression of Nrf2 Transcription Factor in Rat Kidney

Lim JS, Ahn KY

  • KMID: 2080177
  • Korean J Nephrol.
  • 2011 May;30(3):239-245.
PURPOSE: The purpose of this study was to analyze the expression and localization of Nrf2 mRNA in rats according to the changes of K-diet. METHODS: Nrf2 gene was isolated using DNA...
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Dose-dependent effects of busulfan on dog testes in preparation for spermatogonial stem cell transplantation

Hur TY, Lee SH, Ock SA, Song H, Park HJ, Lee R, Sung SH, Jhun H, Lee WY

Successful male germ cell transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan, is commonly used...
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Establishment of a surgically induced cryptorchidism canine recipient model for spermatogonial stem cell transplantation

Lee WY, Lee R, Song H, Hur TY, Lee S, Ahn J, Jhun H

Transplantation of spermatogonial stem cells (SSCs) in experimental animal models has been used to study germ line stem cell biology and to produce transgenic animals. The species-specific recipient model preparation...
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Histologic changes of contralateral scrotal testicle in theunilateral cryptorchidism

Lee SS, Kwon KY, Kim KS

  • KMID: 2114908
  • Korean J Urol.
  • 1992 Oct;33(5):822-826.
Histomorphologic study was performed on bilaterally testicular biopsies of 30 preadolescent patient with unilateral cryptorchidism so as to understand pathophysiology of the increased incidence or infertility, seen in unilateral cryptorchidism....
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