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Allele and haplotype frequencies of 11 human leukocyte antigen loci in Koreans by next-generation sequencing

Oh I, Jung K, Kim JG, Shin S, Roh EY, Hong YJ, Song EY

Background: Data on human leukocyte antigen (HLA) genotype distribution, including DQA1 and DPA1, in the Korean population are limited. We aimed to investigate the allele and haplotype frequencies of 11...
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Evaluation of Five User-Friendly Whole Genome Sequencing Software for Mycobacterium tuberculosis in Clinical Application

Kim N, Seok KH, Shin S, Kim B, Park H, Roh EY, Yoon JH, Shin S

Background: Whole genome sequencing (WGS) is an increasingly useful tool for tuberculosis (TB) diagnosis and disease management. In this study, we evaluated the utility of userfriendly WGS tools in reporting...
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Strong SARS-CoV-2 Antibody Response After Booster Dose of BNT162b2 mRNA Vaccines in Uninfected Healthcare Workers

Kwon SR, Kwon SR, Kim N, Park H, Minn D, Park S, Roh EY, Yoon JH, Shin S

Despite strict guidelines for coronavirus disease 2019 (COVID-19), South Korea is facing its fourth pandemic wave. In this study, by using an automated electrochemiluminescence immunoassay assay, we tracked anti-spike protein...
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HIV-1 Drug Resistance Mutations and Their Clinical Implications in South Korea

Yun J, Jung K, Park JH, Bang JH, Kim N, Roh EY, Shin S, Yoon JH, Park H

Background: While the incidence of new human immunodeficiency virus (HIV) infections has decreased, the dramatic rise in antiretroviral therapy (ART) use will likely increase the prevalence of drug resistance mutations...
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Evaluation of Three Multiplex Realtime Reverse Transcription PCR Assays for Simultaneous Detection of SARS-CoV-2, Influenza A/B, and Respiratory Syncytial Virus in Nasopharyngeal Swabs

Yun J, Park JH, Kim N, Roh EY, Shin S, Yoon JH, Kim TS, Hyunwoong H

Background: In the coronavirus disease 2019 (COVID-19) pandemic era, the simultaneous detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza virus (Flu), and respiratory syncytial virus (RSV) is important...
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Positivity of SARS-CoV-2 Antibodies among Korean Healthy Healthcare Workers 1 and 2 Weeks after Second Dose of Pfizer-BioNTech Vaccination

Kim N, Minn D, Park S, Roh EY, Yoon JH, Park H, Shin S

The antibody titer of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was observed in 289 healthy healthcare workers who had completed the second dose of the Pfizer-BioNTech coronavirus disease...
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Carrier Frequency of Spinal Muscular Atrophy in a Large-scale Korean Population

Park JE, Yun SA, Roh EY, Yoon JH, Shin S, Ki CS

Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by progressive proximal muscle weakness and atrophy. Given the recent introduction of gene therapies, knowledge of the SMA carrier frequency...
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Acute Lymphoblastic Leukemia in a Patient Treated with Letrozole and Palbociclib

Park JH, Park H, Kim KH, Kim JS, Choi IS, Roh EY, Kim JE, Chang MS

Palbociclib, in conjunction with endocrine therapy, has been approved for the treatment of patients with advanced breast cancer. The common hematological toxicities associated with palbociclib are leukopenia and neutropenia. However,...
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Identification of MicroRNA Related to the CD34+ Cell Fraction of Cord Blood Stem Cells

Lee JH, Song EY, Kim N, Roh EY, Park HW, Yoon JH, Shin S

BACKGROUND: Cord blood (CB) is a reliable source of hematopoietic stem cells, and its utilization in stem cell transplantation is increasing continuously. The CD34+ cell count is arguably one of...
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Facklamia hominis Isolated from a Wound: A Case Report and Review of the Literature

Kim TY, Jo J, Kim N, Park H, Roh EY, Yoon JH, Shin S

Facklamia hominis is a facultative anaerobic Gram-positive coccus generally displaying weak alpha-hemolysis and negativity for catalase and oxidase. Facklamia species are part of the normal flora of the female genitourinary...
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A case of immune thrombocytopenia associated with invasive thymoma successfully treated with eltrombopag

Yoon JK, Jang HR, Park JH, Kim KH, Roh EY, Byun JM

No abstract available.
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Golf Swing Rotational Velocity: The Essential Follow-Through

Steele KM, Roh EY, Mahtani G, Meister DW, Ladd AL, Rose J

OBJECTIVE: To evaluate if shoulder and pelvic angular velocities differ at impact or peak magnitude between professional and amateur golfers. Golf swing rotational biomechanics are a key determinant of power...
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Prognostic Influence of Preoperative Fibrinogen to Albumin Ratio for Breast Cancer

Hwang KT, Chung JK, Roh EY, Kim J, Oh S, Kim YA, Rhu J, Kim S

PURPOSE: Elevated serum concentration of fibrinogen and decreased serum concentration of albumin have been reported to be markers of elevated systemic inflammation. We attempted to investigate the prognostic influence of...
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Association of Foxp3 Polymorphism With Allograft Outcome in Kidney Transplantation

Park H, Lee N, In JW, Roh EY, Park KU, Shin S, Yang J, Song EY

BACKGROUND: Forkhead box P3 (Foxp3) is the most reliable marker for regulatory T cells, which play an important role in maintaining renal allograft tolerance. Recently, Foxp3 polymorphisms have been reported...
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Long-Term Quality Control Program Plan for Cord Blood Banks in Korea: A Pilot Study for Cryopreservation Stability

Seo SH, Shin S, Roh EY, Song EY, Oh S, Kim BJ, Yoon JH

BACKGROUND: Maintaining the quality of cryopreserved cord blood is crucial. In this pilot study, we describe the results of the internal quality control program for a cord blood bank thus...
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Reference Intervals of Hematology and Clinical Chemistry Analytes for 1-Year-Old Korean Children

Lee HR, Shin S, Yoon JH, Roh EY, Chang JY

BACKGROUND: Reference intervals need to be established according to age. We established reference intervals of hematology and chemistry from community-based healthy 1-yr-old children and analyzed their iron status according to...
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Effects of Pronase Treatment on Flow Cytometric Crossmatching

Lee N, In JW, Roh EY, Shin S, Song EY

BACKGROUND: Flow cytometric crossmatching (FCXM) is widely used in hospitals performing solid organ transplantation. Pronase treatment of lymphocytes can increase the sensitivity and specificity of B-cell FCXM. However, it can...
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Preparation of Internal Quality Control Material for Lymphocyte Subset Analysis

Roh EY, Shin S, Yoon JH, Oh S, Park KU, Lee N, Song EY

Lymphocyte subset analysis is widely used in clinical laboratories, and more than two levels of daily QC materials are required for reliable results. Commercially available, expensive QC materials have short...
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A Unique Case of Erdheim-Chester Disease with Axial Skeleton, Lymph Node, and Bone Marrow Involvement

Lim J, Kim KH, Suh KJ, Yoh KA, Moon JY, Kim JE, Roh EY, Choi IS, Kim JS, Park JH

Erdheim-Chester disease is a rare non-Langerhans-cell histiocytosis with bone and organ involvement. A 76-year-old man presented with low back pain and a history of visits for exertional dyspnea. We diagnosed...
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Allele and Haplotype Frequencies of Human Leukocyte Antigen-A, -B, -C, -DRB1, and -DQB1 From Sequence-Based DNA Typing Data in Koreans

In JW, Roh EY, Oh S, Shin S, Park KU, Song EY

BACKGROUND: Data on allele frequencies (AFs) and haplotype frequencies (HFs) of HLA-C and -DQB1 are limited in Koreans. We investigated AFs and HFs of HLA-A, -B, -C, -DRB1, and -DQB1...
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