- Effect of Nitric Oxide on ADP-ribose Pyrophosphatase Activity
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Kim JH
- KMID: 1846706
- Immune Netw.
- 2005 Dec;5(4):199-204.
- doi: 10.4110/in.2005.5.4.199
BACKGROUND: ADP-ribosyl pyrophosphatases (ADPRase) has been known to catalyze the hydrolysis of ADP-ribose to ribose-5-phosphate and AMP. The role of ADPRase has been suggested to sanitize the cell by removing... -
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- Comparing the effects of intake of sugar containing different levels of D-ribose in sugar on glycemic index and blood glucose response in healthy adults
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Kim AR, Lee JS, Nam H, Kyung M, Seo S, Chang MJ
- KMID: 2395219
- J Nutr Health.
- 2017 Oct;50(5):426-436.
- doi: 10.4163/jnh.2017.50.5.426
PURPOSE: To compare the extent to which three different levels of D-ribose in sugar reduce the glycemic index (GI) and blood glucose response in healthy adults. METHODS: Healthy adults (eight male... -
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- Inhibitory Effect of Pentose on Biofilm Formation by Oral Bacteria
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Lee YJ, Baek DH
- KMID: 1457214
- Int J Oral Biol.
- 2010 Dec;35(4):203-207.
A number of bacterial species coexist in oral cavities as a biofilm rather than a planktonic arrangement. By forming an oral biofilm with quorum sensing properties, microorganisms can develop a... -
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- Composition and Partial Structure Characterization of Tremella Polysaccharides
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Khondka P
- KMID: 2053029
- Mycobiology.
- 2009 Dec;37(4):286-294.
- doi: 10.4489/MYCO.2009.37.4.286
Heteropolysaccharides isolated from liquid cultures of nine Tremella species contained 0.3 to 1.2% protein, 2.7 to 5% ash, 0.9 to 3.4% acetyl groups, 76.5 to 84.2% carbohydrates and trace amounts... -
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- Enzymatic characterization of Mycobacterium smegmatis ADP-ribosyltransferase
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Song EK, Lee SY, Cho JK, Han MK, Lee HH
- KMID: 2054972
- J Bacteriol Virol.
- 2003 Dec;33(4):293-300.
ADP-ribosyltransferase (ADPRT) catalyzes the reaction in which the ADP-ribose moiety of beta-NAD+ is transferred to specific amino acid residues in target proteins. The ADPRT of Mycobacterium smegmatis has been known... -
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- A Nudix Hydrolase Protein, Ysa1, Regulates Oxidative Stress Response and Antifungal Drug Susceptibility in Cryptococcus neoformans
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Lee KT, Kwon H, Lee D, Bahn YS
- KMID: 2312723
- Mycobiology.
- 2014 Mar;42(1):52-58.
A nucleoside diphosphate-linked moiety X (Nudix) hydrolase-like gene, YSA1, has been identified as one of the gromwell plant extract-responsive genes in Cryptococcus neoformans. Ysa1 is known to control intracellular concentrations... -
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- Biochemical Tests for Differential Identification of Enterococci with VanC phenotype
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Uh Y, Jang IH, Hwang GY, Lee MK, Yoon KJ
- KMID: 1533932
- Korean J Clin Microbiol.
- 2000 Mar;3(1):30-35.
BACKGROUND: Pigment production and acidification of ribose are most frequently used biochemical tests for the differentiation of three enterococcal species carrying vanC genes such as Enterococcus gallinarum, Enterococcus casseliflavus, and... -
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- Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cells
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Park S, Yoon SP, Kim J
- KMID: 2046077
- Anat Cell Biol.
- 2015 Mar;48(1):66-74.
- doi: 10.5115/acb.2015.48.1.66
Treatment with cisplatin for cancer therapy has a major side effect such as nephrotoxicity; however, the role of poly (ADP-ribose) polymerase 1 (PARP1) in necrosis in response to cisplatin nephrotoxicity... -
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- Poly(ADP-ribose) polymerase 1 contributes to oxidative stress through downregulation of sirtuin 3 during cisplatin nephrotoxicity
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Yoon SP, Kim J
- KMID: 2353341
- Anat Cell Biol.
- 2016 Sep;49(3):165-176.
- doi: 10.5115/acb.2016.49.3.165
Enhanced oxidative stress is a hallmark of cisplatin nephrotoxicity, and inhibition of poly(ADP-ribose) polymerase 1 (PARP1) attenuates oxidative stress during cisplatin nephrotoxicity; however, the precise mechanisms behind its action remain... -
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- Spermidine is protective against kidney ischemia and reperfusion injury through inhibiting DNA nitration and PARP1 activation
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Kim J
- KMID: 2390481
- Anat Cell Biol.
- 2017 Sep;50(3):200-206.
- doi: 10.5115/acb.2017.50.3.200
Kidney ischemia and reperfusion injury (IRI) is associated with a high mortality rate, which is attributed to tubular oxidative and nitrative stresses; however, an effective approach to limit IRI remains... -
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- Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells
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Song H, Yoon SP, Kim J
- KMID: 2308914
- Anat Cell Biol.
- 2016 Jun;49(2):79-87.
- doi: 10.5115/acb.2016.49.2.79
After renal injury, selective damage occurs in the proximal tubules as a result of inhibition of glycolysis. The molecular mechanism of damage is not known. Poly(ADP-ribose) polymerase (PARP) activation plays... -
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- Increased Poly (ADP-ribose) Polymerase Activation in the 6-Hydroxydopamine Induced Dopaminergic Neuronal Cell Death
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Kang JH, Kang SY, Park SY, Kang HK, Park DB, Lee YK, Koh JY
- KMID: 2343084
- J Korean Neurol Assoc.
- 2004 Aug;22(4):352-359.
BACKGROUND: The pathological hallmark of Parkinson's disease (PD) is dopaminergic cell death in the substantia nigra (SN), but the cause of cell death is unknown. 6-Hydroxydopamine (6-OHDA) is one of... -
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- Oxidative Stress of INS-1 Cell, HIT-T15 Cell and Rat Islet Cell as a Mechanism of Glucose Toxicity
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Eun MJ, Won KC, Moon JS, Mun SJ, Lee JE, Yoon JS, Chun KA, Cho IH, Lee HW
- KMID: 2008231
- J Korean Diabetes Assoc.
- 2005 Sep;29(5):393-400.
BACKGOUND: Chronic hyperglycemia is the proximate cause of many complications of diabetes. The beta cells in type 2 diabetes are also adversely affected by chronic hyperglycemia, with this relentless deterioration... -
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- Melatonin Induces Apoptotic Cell Death via p53 in LNCaP Cells
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Kim CH, Yoo YM
- KMID: 2071707
- Korean J Physiol Pharmacol.
- 2010 Dec;14(6):365-369.
- doi: 10.4196/kjpp.2010.14.6.365
In this study, we examined whether melatonin promotes apoptotic cell death via p53 in prostate LNCaP cells. Melatonin treatment significantly curtailed the growth of LNCaP cells in a dose- and... -
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- Protein tyrosine phosphatase 1B is a mediator of cyclic ADP ribose-induced Ca²⺠signaling in ventricular myocytes
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Park SA, Hong BZ, Ha KC, Kim UH, Han MK, Kwak YG
- KMID: 2386961
- Exp Mol Med.
- 2017 Jun;49(6):e341.
- doi: 10.1038/emm.2017.68
Cyclic ADP-ribose (cADPR) releases Ca²⺠from ryanodine receptor (RyR)-sensitive calcium pools in various cell types. In cardiac myocytes, the physiological levels of cADPR transiently increase the amplitude and frequency of... -
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- Adaptive Response and Apoptosis Induced by UV Irradiation in Human Keratinocytes and Squamous Cell Carcinomas
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Moon YS
- KMID: 2128897
- Korean J Anat.
- 2007 Dec;40(4):335-345.
The present study was investigated that the effects of suitable ultraviolet (UV) irradiation to the cell viability, apoptosis and expression of poly(ADP-ribose) polymerase (PARP) in HaCaT and KUMA3 cell lines... -
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- Exogenous spermidine ameliorates tubular necrosis during cisplatin nephrotoxicity
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Yoon SP, Kim J
- KMID: 2447012
- Anat Cell Biol.
- 2018 Sep;51(3):189-199.
- doi: 10.5115/acb.2018.51.3.189
The hallmark of cisplatin-induced acute kidney injury is the necrotic cell death in the kidney proximal tubules. However, an effective approach to limit cisplatin nephrotoxicity remains unknown. Spermidine is a... -
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- Amygdalin Regulates Apoptosis and Adhesion in Hs578T Triple-Negative Breast Cancer Cells
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Lee HM, Moon A
- KMID: 2170542
- Biomol Ther.
- 2016 Jan;24(1):62-66.
- doi: 10.4062/biomolther.2015.172
Amygdalin, D-mandelonitrile-beta-D-glucoside-6-beta-glucoside, belongs to aromatic cyanogenic glycoside group derived from rosaceous plant seed. Mounting evidence has supported the anti-cancer effects of amygdalin. However, whether amygdalin indeed acts as an anti-tumor... -
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- Examining the Gm18 and m1G Modification Positions in tRNA Sequences
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Subramanian M, Srinivasan T, Sudarsanam D
- KMID: 2026463
- Genomics Inform.
- 2014 Jun;12(2):71-75.
- doi: 10.5808/GI.2014.12.2.71
The tRNA structure contains conserved modifications that are responsible for its stability and are involved in the initiation and accuracy of the translation process. tRNA modification enzymes are prevalent in... -
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- Scant Extracellular NAD Cleaving Activity of Human Neutrophils is Down-Regulated by fMLP via FPRL1
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Hasan MA, Sultan MT, Ahn WG, Kim YJ, Jang JH, Hong CW, Song DK
- KMID: 2285552
- Korean J Physiol Pharmacol.
- 2014 Dec;18(6):497-502.
- doi: 10.4196/kjpp.2014.18.6.497
Extracellular nicotinamide adenine dinucleotide (NAD) cleaving activity of a particular cell type determines the rate of the degradation of extracellular NAD with formation of metabolites in the vicinity of the... -
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