- Modulation of Dopamine D2 Receptors as a Basis of Antipsychotic Action
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Kim YH, Lee BJ
- KMID: 2286852
- Korean J Psychopharmacol.
- 2004 Sep;15(3):255-262.
As comparing to typical antipsychotics, atypical antipsychotics have several characters such as no causing catalepsy in animal models or extrapyramidal side effects in schizophrenia patients, no or transient prolactin elevation (except risperidone,... -
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- Expression of Dopamine D2 Receptor in Response to Apomorphine Treatment in the Striatum of the Rat with Experimentally Induced Parkinsonism
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Choi SJ, Sung JH, Son BC, Park CK, Kwon SO, Kim MC, Lee SW
- KMID: 1547688
- J Korean Neurosurg Soc.
- 2000 Jul;29(7):868-876.
No abstract available. -
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- Allelic Association of the Dopamine D2Receptor in Korean Alcoholics
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Lee KJ, Lee MS, Kwak DI
- KMID: 1944943
- J Korean Soc Biol Psychiatry.
- 1997 Jun;4(1):43-47.
The author attempted to allelic association between the a1 allele of Dopamine D2 receptor and alcoholism in Korean. The allelic disribution of Taq I polymorphism of the D2 dopamine receptor... -
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- The Relationship between Taq I A Dopamine D2 Receptor Polymorphism and Therapeutic Response to Antipsychotics in Schizophrenic Patients
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Kang CJ
- KMID: 2299952
- Korean J Biol Psychiatry.
- 2005 Nov;12(2):107-113.
PURPOSE: In an attempt to predict the interpersonal differences of therapeutic response to antipsychotic drugs on pharmaco-genetic bases, this study was designed to investigate the relationship between the therapeutic response... -
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- Association between the Alleles of the Dopamine D, Receptor and Schizophrenia
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Kim JI, Lee MS, Kwak DI
- KMID: 2202983
- J Korean Soc Biol Psychiatry.
- 1997 Nov;4(2):218-224.
The results regarding an association between the polymorphism sites in the dopamine D1 receptor gene and schizophrenia compelled us to study the distribution of the polymorphism in Korean schizophrenia and... -
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- Risperidone-Induced Amenorrhea in a Premenopausal Woman with Schizophrenia
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Kim YK, Kim L, Lee MS
- KMID: 2340190
- J Korean Neuropsychiatr Assoc.
- 1998 Jul;37(4):758-761.
The incidence of risperidone-induced amenorrhea has not been well known. Since conven tional antipsyrchotics-induced amenorrhea may be due to the hyperprolactinemia associated with the block of dopamine D2 receptor, it... -
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- Association of Dopamine D2 Receptor Ser311 -> Cys311 Polymorphism with Korean Schizophrenic Patients
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Lee BH, Chee IS, Shin SC
- KMID: 2340083
- J Korean Neuropsychiatr Assoc.
- 1997 Jul;36(4):742-749.
A new structural polymorphism(Ser311 -> Cys311) in the dopamine D, receptor gene has been reported to be associated with schizophrenia, particularly in patients with a positive family history of schizophrenia.... -
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- Increased expression of dopamine receptors and transporter and hypomethylation of dopamine transporter gene in uterine leiomyoma
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Kim JH, Kim MJ, Choo YA, Choi YS, Lee TS, Kim HT
- KMID: 2128061
- Korean J Obstet Gynecol.
- 2005 Mar;48(3):628-637.
OBJECTIVE: Dopamine plays a key role in the proliferation regulation of the smooth muscle cells. The purpose of this study was to observe the degree of expression of dopamine D1... -
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- Trial of Metoclopramide on Oro-facial Dyskinesia Following Traumatic Brain Injury: A Case Report
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Kim SK, Kim JY, Kim HS
- KMID: 1797650
- Brain Neurorehabil.
- 2014 Sep;7(2):147-150.
- doi: 10.12786/bn.2014.7.2.147
Oro-facial dyskinesia is characterized by involuntary repetitive movements of the tongue, lip, or jaw, which is known to be derived by variable causes. Pre- and post-synaptic dopamine receptor abnormalities by... -
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- Role of Dopamine Receptors on Electroencephalographic Changes Produced by Repetitive Apomorphine Treatments in Rats
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Jang HS, Kim JY, Kim SH, Lee MG
- KMID: 2071664
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):147-151.
- doi: 10.4196/kjpp.2009.13.3.147
Repeated psychostimulants induce electroencephalographic (EEG) changes, which reflect adaptation of the neural substrate related to dopaminergic pathways. To study the role of dopamine receptors in EEG changes, we examined the... -
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- Cocaine-Induced Behavioral Sensitization in Mice: Effects of Microinjection of Dopamine D2 Receptor Antagonist into the Nucleus Accumbens
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Jung ES, Lee HJ, Sim HR, Baik JH
- KMID: 2165485
- Exp Neurobiol.
- 2013 Sep;22(3):224-231.
- doi: 10.5607/en.2013.22.3.224
To determine the role of dopamine D2 receptor (D2R) in the nucleus accumbens (NAc) core in cocaine-induced behavioral sensitization, D2R antagonist, raclopride was bilaterally microinjected (2.5 or 5 nmol) into... -
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- No Association between DRD2 polymorphism Ser311/Cys311 and Bipolar Disorder in Korean Population
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Hur TW, Chee IS, Lee YH
- KMID: 2340404
- J Korean Neuropsychiatr Assoc.
- 1999 Nov;38(6):1488-1493.
OBJECTIVES: This study was designed to investigate the association between Ser311/Cys311 polymorphism in the dopamine D2 receptor gene and bipolar disorder in korean population. METHOD: Ser311/Cys311 polymorphism in the dopamine D2... -
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- Interactions of Dopamine D1 and N-methyl-D-Aspartate Receptors are Required for Acute Cocaine-Evoked Nitric Oxide Efflux in the Dorsal Striatum
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Lee DK, Ahn SM, Shim YB, Koh WC, Shim I, Choe ES
- KMID: 2052824
- Exp Neurobiol.
- 2011 Jun;20(2):116-122.
- doi: 10.5607/en.2011.20.2.116
Alterations in nitric oxide (NO) release in response to psychostimulants in the striatum cause a plastic change contributing to the development and expression of addiction. In this study, regulation of... -
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- Role of Helix 8 in Dopamine Receptor Signaling
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Yang HS, Sun N, Zhao X, Kim HR, Park HJ, Kim KM, Chung KY
- KMID: 2462878
- Biomol Ther.
- 2019 Nov;27(6):514-521.
- doi: 10.4062/biomolther.2019.026
G protein-coupled receptors (GPCRs) are membrane receptors whose agonist-induced dynamic conformational changes trigger heterotrimeric G protein activation, followed by GRK-mediated phosphorylation and arrestin-mediated desensitization. Cytosolic regions of GPCRs have been... -
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- Association Study between Tic Disorder and Dopamine D2 Receptor Gene Polymorphism in Korean Population
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Lee SI, Cho IH, Kim SM, Lee MS, Jung HY
- KMID: 2299949
- Korean J Biol Psychiatry.
- 2006 Nov;13(4):299-304.
OBJECTIVES: The purpose of the present study was to investigate whether the Taq I A polymorphism of dopamine receptor D2 gene(DRD2) is associated with Tourette syndrome(TS) and chronic motor tic... -
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- The Relationship between the Amisulpride-Induced Hyperprolactinemia and Taq1A Polymorphism of the Dopamine D2 Receptor Gene in Schizophrenia Patients
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Kim JJ, Seo MJ, Choi TY, Lee JH
- KMID: 2371181
- Korean J Biol Psychiatry.
- 2017 Feb;24(1):32-38.
- doi: 10.0000/kjbp.2017.24.1.32
OBJECTIVES: This study was aimed to investigate the association between amisulpride-induced hyperprolactinemia and the Taq1A polymorphism in the D2 dopamine receptor gene (DRD2) in schizophrenic patients. METHODS: The plasma concentrations of... -
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- Dopaminergic inhibition of dorsal horn cell activity in the cat
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Kim KC, Shin HK, Kim KS
- KMID: 2071824
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):661-670.
Dopamine has been generally known to exert antinociceptive action in behavioral pain test, such as tail flick and hot plate test, but there appears to be a great variance in the reports... -
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- Detection of DRD2 SER311CYS Variant in Schizophrenic Patients
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Lim WJ
- KMID: 1964831
- Ewha Med J.
- 1999 Dec;22(4):265-272.
- doi: 10.12771/emj.1999.22.4.265
OBJECTIVES: The molecular pathogenesis of the schizophrenia has been extensively studied. The dopamine hypothesis is well-known possible mechanism in the etiology of schizophrenia and dopamine D2 receptor gene(DRD2 gene), one... -
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- Effect of Acute and Chronic Treatment with Risperidone on the Serotonin and Dopamine Receptors in the Rat Brain
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Choi YY, Miin DH, Son HK, Kim CY, Lee C, Lee HK
- KMID: 1991101
- Korean J Nucl Med.
- 1997 Mar;31(1):9-18.
The therapeutic efficacy of antipsychotic drugs is generally attributed to their ability to block dopamine D2 receptors. Classical D2 antagonists are not effective to treat negative symptoms and produce extrapyramidal... -
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- An Association Study of the Dopamine D2 Receptor Taq1A Polymorphism and Temperament in Korean Pathological Gamblers
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Kwon YS, Lim S, Shin YC
- KMID: 2250133
- Korean J Biol Psychiatry.
- 2011 Aug;18(3):119-125.
OBJECTIVE: It has been suggested that the dopamine D2 receptor gene (DRD2) is associated with pathological gambling (PG). We investigated the association of the DRD2 Taq1A polymorphism and the temperament... -
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