- The Function of the Vitamin D Receptor and a Possible Role of Enhancer RNA in Epigenomic Regulation of Target Genes: Implications for Bone Metabolism
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Sawatsubashi S, Nishimura , Mori J, Kouzmenko , Kato S
- KMID: 2440639
- J Bone Metab.
- 2019 Feb;26(1):3-12.
- doi: 10.11005/jbm.2019.26.1.3
Vitamin D (VD) is essential for bone health, and VD or its analogues are widely used in clinics to ameliorate bone loss. The targets and mode of VD anti-osteoporotic actions... -
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- The Levels of Vitamin D, Vitamin D Receptor, Homocysteine and Complex B Vitamin in Children with Autism Spectrum Disorders
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Altun H, Kurutaş E, Şahin N, Güngör O, Fındıklı E
- KMID: 2428967
- Clin Psychopharmacol Neurosci.
- 2018 Nov;16(4):383-390.
- doi: 10.9758/cpn.2018.16.4.383
OBJECTIVE: Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome with an increasingly prevalent etiology, yet not fully understood. It has been thought that vitamin D, complex B vitamin levels... -
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- Vitamin D Status and Vitamin D Receptor Gene Polymorphisms Are Associated with Pelvic Floor Disorders in Women
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Ahn JH, Noh YH, Um KJ, Kim HS, Cho S
- KMID: 2419621
- J Menopausal Med.
- 2018 Aug;24(2):119-126.
- doi: 10.6118/jmm.2018.24.2.119
OBJECTIVES: To investigate if vitamin D receptor (VDR) gene polymorphisms and circulating vitamin D levels are associated with pelvic floor disorders (PFDs). METHODS: In this case-control study, 25-hydroxy-vitamin D (25[OH]D) serum... -
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- Vitamin D Receptor Gene, Matrix Metalloproteinase 3 Polymorphisms and the Risk of Intervertebral Disc Degeneration Susceptibility: Meta-Analysis
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Nong L, Huang Y, Zhao S, Xu N
- KMID: 2354825
- Asian Spine J.
- 2016 Oct;10(5):964-971.
- doi: 10.4184/asj.2016.10.5.964
Several studies have evaluated the association between vitamin D receptor, matrix metalloproteinase 3 (MMP-3) polymorphisms and the risk of intervertebral disc degeneration susceptibility. The findings were inconsistent. This meta-analysis aimed... -
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- Quercetin Directly Interacts with Vitamin D Receptor (VDR): Structural Implication of VDR Activation by Quercetin
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Lee KY, Choi HS, Choi HS, Chung KY, Lee BJ, Maeng HJ, Seo MD
- KMID: 2170532
- Biomol Ther.
- 2016 Mar;24(2):191-198.
- doi: 10.4062/biomolther.2015.122
The vitamin D receptor (VDR) is a member of the nuclear receptor (NR) superfamily. The VDR binds to active vitamin D3 metabolites, which stimulates downstream transduction signaling involved in various... -
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- Association between Bsm1 Polymorphism in Vitamin D Receptor Gene and Diabetic Retinopathy of Type 2 Diabetes in Korean Population
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Hong YJ, Kang ES, Ji MJ, Choi HJ, Oh T, Koong SS, Jeon HJ
- KMID: 2169654
- Endocrinol Metab.
- 2015 Dec;30(4):469-474.
- doi: 10.3803/EnM.2015.30.4.469
BACKGROUND: Type 2 diabetes is one of the most common diseases with devastating complications. However, genetic susceptibility of diabetic complications has not been clarified. The vitamin D endocrine system is... -
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- Expression of Vitamin D Receptor in Seminal Vesicles of Cholesterol Formula Mice
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Kim TH, Lee HH, Kim JM, Choi SD, Lee A, Hwang SY, Kim M, Kim YS, Yeom S
- KMID: 2200984
- J Menopausal Med.
- 2015 Aug;21(2):89-92.
- doi: 10.6118/jmm.2015.21.2.89
OBJECTIVES: Genomic function of vitamin D receptor (VDR) indicates spermatogenesis that is important for in male reproductive organ authors evaluated the VDR expression in seminal vesicles with high cholesterol (HC)... -
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- Vitamin D Receptor Poly(A) Microsatellite Polymorphism and 25-Hydroxyvitamin D Serum Levels: Association with Susceptibility to Breast Cancer
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Colagar AH, Firouzjah , Halalkhor
- KMID: 2374526
- J Breast Cancer.
- 2015 Jun;18(2):119-125.
- doi: 10.4048/jbc.2015.18.2.119
PURPOSE: According to previous studies, vitamin D exhibits protective effects against breast cancer via the vitamin D receptor (VDR). There is growing evidence that breast cancer incidence is associated with... -
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- Vitamin D Receptor Genotype is Associated with Secondary Hyperparathyroidism in Hemodialysis Patients
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Yoon SI, Oh TK, Kwon SK, Kim HY
- KMID: 2079687
- Korean J Nephrol.
- 2007 May;26(3):320-326.
PURPOSE: It is known that secondary hyperparathyroidism in end stage renal disease (ESRD) patients is associated with vitamin D receptor (VDR) gene polymorphism, but there is no consensus on its... -
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- Association of Calcium Intake and Bone Mineral Density by Vitamin D Receptor Genotype among Elderly Women Living in Rural a Area
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Kim JS, Kim HS
- KMID: 2235938
- Korean J Community Nutr.
- 2006 Aug;11(4):534-540.
Recent studies have shown that environmental, biochemical, nutritional or genetic factors affect bone mineral density (BMD). The purpose of the present study was to investigate the effect of vitamin D... -
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- Vitamin D Receptor Gene BsaM I Polymorphism as Genetic Marker in Patients with Calcium Stone
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Seo IY, Park KW, Park SC, Lee SJ, Kim MS, Kim JJ, Rim JS
- KMID: 2293257
- Korean J Urol.
- 2004 Nov;45(11):1143-1147.
PURPOSE: To identify candidate genes related with urolithiasis, the vitamin D receptor (VDR) gene polymorphisms were searched. MATERIALS AND METHODS: Between July 2002 and June 2003, 212 healthy subjects, used as... -
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- The Relationship between Vitamin D Receptor Gene Polymorphisms and the Effect of Hormone Replacement Therapy on Bone Mineral Density in Postmenopausal Korean Women
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Kim JG, Kim SH, Choi YM, Moon SY, Lee JY
- KMID: 2272041
- Korean J Obstet Gynecol.
- 2003 May;46(5):984-990.
OBJECTIVE: to investigate whether vitamin D receptor (VDR) gene polymorphisms are associated with the effect of hormone replacement therapy (HRT) on bone mineral density (BMD) in postmenopausal Korean women. METHODS: The... -
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- Association of Vitamin D Receptor, Estrogen Receptor, Transforming Growth Factor-beta1 and Interleukin-6 Gene Polymorphism with Bone Mass in Postmenopausal Korean Women
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Kwon DJ, You YO, Kim DH, Jo HH, Kim JH, Jong BW, Lim YT, Kim EJ, Lee JW, Kim JH
- KMID: 2272031
- Korean J Obstet Gynecol.
- 2003 May;46(5):913-921.
OBJECTIVE: To evaluate the relationship between vitamin D receptor (VDR), estrogen receptor (ER), transforming growth factor-beta1 (TGF-beta1) and interleukin-6 (IL-6) gene polymorphism, and bone mineral density (BMD). MATERIALS AND METHODS: Restriction... -
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- Relationship Between Poly (A) Microsatellite in Vitamin D Receptor Gene, and Bone Mineral Density in Postmenopausal Korean Women
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Kim JG, Kwon JH, Kim SH, Choi YM, Moon SY, Lee JY
- KMID: 2272012
- Korean J Obstet Gynecol.
- 2003 Apr;46(4):795-801.
OBJECTIVE: To investigate a poly (A) microsatellite in vitamin D receptor (VDR) gene and to evaluate its relationship with bone mineral density (BMD) in postmenopausal Korean women. METHODS: The poly (A)... -
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- Vitamin D Receptor Gene 3' End Polymorphisms in Patients with Graves' Disease in Koreans
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Hwang JK, Kim KW, Kim TY, Lee HS, Park YJ, Shin CS, Park DJ, Park KS, Rhee BD, Kim SY, Lee HK, Cho BY
- KMID: 2200123
- J Korean Soc Endocrinol.
- 2003 Feb;18(1):12-23.
BACKGROUND: The aim of this study was to evaluate the association of vitamin D receptor (VDR) gene polymorphisms with Graves' disease in Koreans. We also investigated the association of VDR... -
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- Relationship between vitamin D receptor gene polymorphism, and bone mineral density in postmenopausal Korean women
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Kim JG, Kwon JH, Kim SH, Choi YM, Moon SY, Lee JY
- KMID: 2076742
- Korean J Obstet Gynecol.
- 2002 Nov;45(11):1982-1990.
OBJECTIVE: To investigate the relationship between vitamin D receptor (VDR) gene polymorphisms and bone mineral density (BMD) in postmenopausal Korean women, and to evaluate if VDR gene polymorphisms are associated... -
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- Lack of association between rheumatoid arthritis and vitamin D receptor polymorphisms in Koreans
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Yoon WC, Kim CG, Song YH, Kim SG, Joen CH, Kim OD, Choe JY
- KMID: 2252915
- Korean J Med.
- 2002 Feb;62(2):209-217.
BACKGROUND: The purpose of this study was to determine whether the distribution of vitamin D receptor (VDR) polymorphisms in rheumatoid arthritis (RA) patients group is different from that of the... -
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- The Vitamin D Receptor Start Codon Polymorphism (SCP) and Bone Mineral Density in Korean Women
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Chung DJ, Cheon NI, Lee CH, Cho DH, Kang HC, Chung MY, Park JT, Yang SW
- KMID: 2274996
- Chonnam Med J.
- 2001 Sep;37(3):277-283.
Bone mineral density (BMD) is thought to be under strong genetic control. Polymorphisms of the vitamin D receptor (VDR) gene have recently been suggested to account for some of the... -
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- Association Between Peak Bone Mass and Genetic Polymorphisms of the Vitamin D Receptor, Estrogen Receptor, and Type I Collagen 1 Genes in Healthy Young Korean Women
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Kim HK, Kim SW, Kim ES, Kim GS
- KMID: 2331160
- J Korean Soc Endocrinol.
- 2001 Feb;16(1):97-114.
BACKGROUND: Genetic suggest that strongest effect is observed in the premenopausal peak bone mass, which become less with age. However, the evaluation of candidate genes polymorphisms has been most frequently... -
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- A Relationship Between Polymorphism of Vitamin D Receptor Gene and Bone Mineral Density in Postmenopausal Women of Korea
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Lee JY, Chung HW, Kim HR, Ahn JJ, Yoo HK
- KMID: 2075729
- Korean J Obstet Gynecol.
- 1999 Apr;42(4):880-886.
OBJECTIVE: The goal of this study was to determine the relationship between BMD and polymorphism of vitamine D receptor gene. METHOD: We amplified exon 2 of VDR and its digestion... -
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