- Identification of Atg8 Isoform in Encysting Acanthamoeba
-
Moon EK, Hong Y, Chung DI, Kong HH
- KMID: 1792139
- Korean J Parasitol.
- 2013 Oct;51(5):497-502.
Autophagy-related protein 8 (Atg8) is an essential component of autophagy formation and encystment of cyst-forming parasites, and some protozoa, such as, Acanthamoeba, Entamoeba, and Dictyostelium, have been reported to possess... -
- CITED
-
- Close
- SHARE
-
- Close
- Gene expression responses in vivo by human telomerase reverse transcriptase (hTERT)-targeting trans-splicing ribozyme
-
Song MS, Jeong JS, Cho KS, Lee SW
- KMID: 1091067
- Exp Mol Med.
- 2007 Dec;39(6):722-732.
A trans-splicing ribozyme which can specifically reprogram human telomerase reverse transcriptase (hTERT) RNA was previously suggested as a useful agent for tumor-targeted gene therapy. In this study, we evaluated in... -
- CITED
-
- Close
- SHARE
-
- Close
- Regulation of bcl-2 family in hydrogen peroxide-induced apoptosis in human leukemia HL-60 cells
-
Lee JE, Sohn JW, Lee JH, Lee KC, Son CS, Tockgo YC
- KMID: 927133
- Exp Mol Med.
- 2000 Mar;32(1):42-46.
Numerous types of cells have been shown to undergo apoptosis when exposed to oxidant agent such as hydrogen peroxide. In order to understand the functional relationship between the anti- and... -
- CITED
-
- Close
- SHARE
-
- Close
- A known expressed sequence tag, BM742401, is a potent lincRNA inhibiting cancer metastasis
-
Park SM, Park SJ, Kim HJ, Kwon OH, Kang TW, Sohn HA, Kim SK, Moo Noh S, Song KS, Jang SJ, Sung Kim Y, Kim SY
- KMID: 2154250
- Exp Mol Med.
- 2013 Jul;45(7):e31.
Long intergenic non-coding RNAs (lincRNAs) have historically been ignored in cancer biology. However, thousands of lincRNAs have been identified in mammals using recently developed genomic tools, including microarray and high-throughput... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of Exogenous Human Hepatic Nuclear Factor-1alpha by a Lentiviral Vector and Its Interactions with Plasmodium falciparum Subtilisin-Like Protease 2
-
Liao S, Liu Y, Zheng B, Cho PY, Song HO, Lee YS, Jung SY, Park H
- KMID: 1715752
- Korean J Parasitol.
- 2011 Dec;49(4):431-436.
- doi: 10.3347/kjp.2011.49.4.431
The onset, severity, and ultimate outcome of malaria infection are influenced by parasite-expressed virulence factors as well as by individual host responses to these determinants. In both humans and mice,... -
- CITED
-
- Close
- SHARE
-
- Close
- The Wnt/beta-catenin signaling pathway regulates the development of airway remodeling in patients with asthma
-
Kwak HJ, Park DW, Seo JY, Moon JY, Kim TH, Sohn JW, Shin DH, Yoon HJ, Park SS, Kim SH
- KMID: 2359885
- Exp Mol Med.
- 2015 Dec;47(12):e198.
- doi: 10.1038/emm.2015.91
Airway remodeling is a key characteristic of chronic asthma, particularly in patients with a fixed airflow limitation. The mechanisms underlying airway remodeling are poorly understood, and no therapeutic option is... -
- CITED
-
- Close
- SHARE
-
- Close
- miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes
-
Makki MS, Haqqi TM
- KMID: 2160620
- Exp Mol Med.
- 2015 Oct;47(10):e189.
- doi: 10.1038/emm.2015.66
IL-6 is an inflammatory cytokine and its overexpression plays an important role in osteoarthritis (OA) pathogenesis. Expression of IL-6 is regulated post-transcriptionally by MCPIP1. The 3' untranslated region (UTR) of... -
- CITED
-
- Close
- SHARE
-
- Close
- Characterization of aberrant FHIT transcripts in gastric adenocarcinomas
-
Lee SH, Kim CJ, Park HK, Koh JW, Cho MH, Baek MJ, Lee MS
- KMID: 938875
- Exp Mol Med.
- 2001 Sep;33(3):124-130.
Aberrant transcripts of FHIT (fragile histidine triad) have been reported in several types of primary tumors and cell lines, including gastric carcinoma. The role of these aberrant transcripts in tumorigenesis... -
- CITED
-
- Close
- SHARE
-
- Close
- B-cell-activating factor is a regulator of adipokines and a possible mediator between adipocytes and macrophages
-
Kim MY, Kim DH, Do MS
- KMID: 2154223
- Exp Mol Med.
- 2013 Jan;45(1):e4.
3T3-L1 adipocytes express the B-cell-activating factor (BAFF) and three different BAFF receptors (BAFF-Rs). Furthermore, BAFF expression is regulated by inflammatory modulators, such as tumor necrosis factor-alpha and rosiglitazone. Here we... -
- CITED
-
- Close
- SHARE
-
- Close
- Urinary Nucleic Acid TSPAN13-to-S100A9 Ratio as a Diagnostic Marker in Prostate Cancer
-
Yan C, Kim YH, Kang HW, Seo SP, Jeong P, Lee IS, Kim D, Kim JM, Choi YH, Moon SK, Yun SJ, Kim WJ
- KMID: 2359962
- J Korean Med Sci.
- 2015 Dec;30(12):1784-1792.
- doi: 10.3346/jkms.2015.30.12.1784
The potential use of urinary nucleic acids as diagnostic markers in prostate cancer (PCa) was evaluated. Ninety-five urine samples and 234 prostate tissue samples from patients with PCa and benign... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of the nm23-H1 gene in the metastasis of gastric cancer
-
Hwang BG, Park IC, Park MJ, Moon NM, Choi DW, Hong WS, Lee SH, Hong SI
- KMID: 645111
- J Korean Med Sci.
- 1997 Dec;12(6):514-518.
- doi: 10.3346/jkms.1997.12.6.514
The nm23 gene is now generally accepted as one of the suppressor genes for metastasis in many types of human cancer. To investigate the role of the nm23 gene... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification of abnormal gene expression in bovine transgenic somatic cell nuclear transfer embryos
-
Cho J, Kang S, Lee BC
- KMID: 1784643
- J Vet Sci.
- 2014 Jun;15(2):225-231.
- doi: 10.4142/jvs.2014.15.2.225
This study was conducted to investigate the expression of three genes related to early embryonic development in bovine transgenic cloned embryos. To accomplish this, development of bovine transgenic somatic cell... -
- CITED
-
- Close
- SHARE
-
- Close
- Value of urinary topoisomerase-IIA cell-free DNA for diagnosis of bladder cancer
-
Kim YH, Yan C, Lee IS, Piao XM, Byun YJ, Jeong P, Kim WT, Yun SJ, Kim WJ
- KMID: 2363132
- Investig Clin Urol.
- 2016 Mar;57(2):106-112.
- doi: 10.4111/icu.2016.57.2.106
PURPOSE: Topoisomerase-II alpha (TopoIIA ), a DNA gyrase isoform that plays an important role in the cell cycle, is present in normal tissues and various human cancers, and can show... -
- CITED
-
- Close
- SHARE
-
- Close
- miR-27 regulates mitochondrial networks by directly targeting the mitochondrial fission factor
-
Tak H, Kim J, Jayabalan , Lee H, Kang H, Cho DH, Ohn T, Nam SW, Kim W, Lee EK
- KMID: 2155388
- Exp Mol Med.
- 2014 Nov;46(11):e123.
- doi: 10.1038/emm.2014.73
Mitochondrial morphology is dynamically regulated by forming small, fragmented units or interconnected networks, and this is a pivotal process that is used to maintain mitochondrial homeostasis. Although dysregulation of mitochondrial... -
- CITED
-
- Close
- SHARE
-
- Close
- Depletion of mitochondrial DNA up-regulates the expression of MDR1 gene via an increase in mRNA stability
-
Lee W, Choi HI, Kim MJ, Park SY
- KMID: 1103594
- Exp Mol Med.
- 2008 Feb;40(1):109-117.
- doi: 10.3858/emm.2008.40.1.109
The mutation and reduction of mitochondrial DNA (mtDNA) have been suggested as factors in the carcinogenesis. However, whether the depletion of mtDNA induces multidrug resistance in cancer cells has not... -
- CITED
-
- Close
- SHARE
-
- Close
- Downregulation of Orai1 expression in the airway alleviates murine allergic rhinitis
-
Wang Y, Lin L, Zheng C
- KMID: 1245261
- Exp Mol Med.
- 2012 Mar;44(3):177-190.
- doi: 10.3858/emm.2012.44.3.013
Orai1 is the key subunit of the Ca2+-release-activated Ca2+ channel. Our previous report has demonstrated that Orai1 expression in the airway was upregulated in the ovalbumin (OVA)-induced allergic rhinitis (AR)... -
- CITED
-
- Close
- SHARE
-
- Close
- p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line
-
Jiang A, Yu C, Zhang P, Chen W, Liu W, Hu X, Zhang J
- KMID: 1115940
- Exp Mol Med.
- 2006 Dec;38(6):625-633.
Prostate cancer is a disease involving complicated multiple-gene alterations. Both NKX3.1 and p53 are related to prostate cancer and play crucial roles in prostate cancer progression. However, little is known... -
- CITED
-
- Close
- SHARE
-
- Close
- Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy
-
Yu T, Tang B, Sun X
- KMID: 2419104
- Yonsei Med J.
- 2017 May;58(3):489-496.
- doi: 10.3349/ymj.2017.58.3.489
Hypoxia is frequently observed in solid tumors and also one of the major obstacles for effective cancer therapies. Cancer cells take advantage of their ability to adapt hypoxia to initiate... -
- CITED
-
- Close
- SHARE
-
- Close
- Cloning, expression and functional analysis of the duck Toll-like receptor 5 (TLR5) gene
-
Cheng Y, Sun Y, Wang H, Shi S, Yan Y, Li J, Ding C, Sun J
- KMID: 2160819
- J Vet Sci.
- 2015 Mar;16(1):37-46.
- doi: 10.4142/jvs.2015.16.1.37
Toll-like receptor 5 (TLR5) is responsible for the recognition of bacterial flagellin in vertebrates. In the present study, the first TLR5 gene in duck was cloned. The open reading frame... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Nitric Oxide on the Expression of Matrix Metalloproteinase and Its Association with Migration of Cultured Trabecular Meshwork Cells
-
Kim JW
- KMID: 2363893
- Korean J Ophthalmol.
- 2016 Feb;30(1):66-75.
- doi: 10.3341/kjo.2016.30.1.66
PURPOSE: To determine the effect of exogenous nitric oxide (NO) on the migration of trabecular meshwork (TM) cells and its association with expression of matrix metalloproteinases (MMPs). METHODS: Primary human TM... -
- CITED
-
- Close
- SHARE
-
- Close
