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Expression of volume-activated anion channels in exocrine acinar cells

Park K, Majid A

No abstract available.
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Upregulated expression of the cDNA fragment possibly related to the virulence of Acanthamoeba culbertsoni

Im KI, Park KM, Yong TS, Hong YP, Kim TE

Identification of the genes responsible for the recovery of virulence in brain-passaged Acanthamoeba culbertsoni was attempted via mRNA differential display-polymerase chain reaction (mRNA DD-PCR) analysis. In order to identify...
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Role of the nm23-H1 gene in the metastasis of gastric cancer

Hwang BG, Park IC, Park MJ, Moon NM, Choi DW, Hong WS, Lee SH, Hong SI

The nm23 gene is now generally accepted as one of the suppressor genes for metastasis in many types of human cancer. To investigate the role of the nm23 gene...
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The mechanism of c-erbB-2 gene product increase in stomach cancer cell lines

Bae CD, Park SE, Seong YS, Kim SW, park JB, Park JG

c-erbB-2 oncogene encodes a growth factor receptor whose amino acid sequence has extensive homology with human epidermal growth factor receptor. It is frequently overexpressed in human breast, ovary, lung, and...
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Cyclin-Dependent Kinase Inhibitor p27(Kip1) Controls Growth and Cell Cycle Progression in Human Uterine Leiomyoma

Ramachandran S, Kwon KY, Shin SJ, Kwon SH, Cha SD, Bae I, Cho CH

The molecular mechanism of the cell-cycle machinery in uterine leiomyoma has not yet been fully elucidated. Among the various types of cell-cycle regulators, p27(Kip1)(p27) is considered to be a potent...
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Comparison of oligonucleotide-microarray and serial analysis of gene expression (SAGE) in transcript profiling analysis of megakaryocytes derived from CD34+ cells

Kim HL

  • KMID: 1093620
  • Exp Mol Med.
  • 2003 Oct;35(5):460-466.
For the comprehensive analysis of transcript expression, the array-based hybridization analysis and the serial analysis of gene expression (SAGE) are commonly used platforms. The SAGE is based on a high-throughput...
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Interleukin-8 gene expression in the human colon epithelial cell line, HT-29, exposed to Entamoeba histolytica

Kim JM, Jung HC, Im K, Cho YJ, Kim CY

The protozoan parasite, Entamoeba histolytica, is one of major causative agents of intestinal disease all over the world. In acute experimental infection, the early host response to E. histolytica is...
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Identification of differentially expressed genes in gauze-exposed omentum of dogs using differential display RT-PCR

Rahman MM, Kim Y, Byeon YE, Ryu HH, Kim WH, Rayhan MU, Kweon OK

Molecular mechanisms governing peritonitis caused by the presence of aseptic gauze have remained unclear. To identify the genes involved, sterile gauze-exposed omentum was collected at 0, 6, 12, 24, and...
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Thalidomide Accelerates the Degradation of Extracellular Matrix in Rat Hepatic Cirrhosis via Down-Regulation of Transforming Growth Factor-beta1

Lv P, Meng Q, Liu J, Wang C

PURPOSE: The degradation of the extracellular matrix has been shown to play an important role in the treatment of hepatic cirrhosis. In this study, the effect of thalidomide on the...
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Comparison of p53 gene mutations in paired primary and metastatic gastric tumor tissues

Kim JH, Choi JJ, Noh SH, Roh JK, Min JS, Youn JK, Yoo NC, Lim HY, Carbone DP, Gazdar AF, Lee KS, Kim BS

Our previous study revealed that mutations of the p53 gene were detected by cDNA sequencing in one of four (25%) primary gastric tumors and in five of six (83%) gastric...
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Identification of CD44 splice variant in Korean colorectal cancers and cell lines

Suh SI, Baek WK, Park JW, Bae OS, Suh MH, Choe BK

CD44 is a glycoprotein expressed in a wide variety of cell types. Recently expression of some alternatively-spliced variants of CD44 transcripts (CD44v) has been suggested to play a potential role...
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Clinical Impacts of Tumor Cell Contamination of Hematopoietic Stem Cell Products in Metastatic Breast Cancer Patients undergoing Autologous Peripheral Blood Stem Cell Transplantation: Multicenter Trial

Ahn MJ, Noh YH, Lee YS, Lee YY, Choi IY, Kim IS, Joh EK, Shin DB, Kim SY, Cho KS, Kim HC, Kim HS, Suh CW, Kim SH, Lee JA, Park YS

To determine whether the tumor cell contamination of peripheral blood stem cells influences clinical impacts on high-dose chemotherapy in patients with metastatic breast cancer, we analyzed carcinoembryonic antigen (CEA) mRNA...
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The detection of circulating breast cancer cells in peripheral blood by reverse transcriptase-polymerase chain reaction

Bae JW, Choi KH, Kim HG, Park SH

Some circulating cancer cells in the blood play a central role in the metastatic process and may have a major influence on patient progress. Their numbers can be very small...
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Hyperoxia influences mRNA expression of cytokines in cultured human umbilical vein endothelial cells

Park MS, Wallace HM

High concentrations of oxygen, indispensable for the treatment of severe hypoxemia from neonatal as well as adult respiratory distress syndrome, increase the risk of oxygen toxicity. Biochemical mechanisms are lipid...
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Real-Time PCR analysis of af4 and dek genes expression in acute promyelocytic leukemiat (15;17)patients

Savli H, Sirma S, Nagy B, Aktan M, Dincol G, Salcioglu , Sarper N, Ozbek U

  • KMID: 1097111
  • Exp Mol Med.
  • 2004 Jun;36(3):279-282.
Among several newly identified oncogenes, dek and af4 are attractive targets for researchers interested with leukemia. In this study quantitative Real-Time RT-PCR technique was used to define alterations in expression...
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The Regulators of VEGF Expression in Mouse Ovaries

Shin SY, Lee HJ, Ko DS, Lee HC, Park WI

The objectives of this study were to explore whether ovarian vascular endothelial growth factor (VEGF) expression in mice can be regulated by IL-6 (interleukin-6), angiotensin II, FSH, and hCG; and...
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Role of tissue inhibitors of metalloproteinases (TIMPs) in colorectal carcinoma

Joo YE, Seo KS, Kim J, Kim HS, Rew JS, Park CS, Kim SJ

Increased production of matrix metalloproteinases (MMPs) has been associated with increases in invasive and metastatic potential in many types of human carcinoma. Tissue inhibitors of metalloproteinase (TIMP)-1 inhibits most interstitial...
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Representational difference analysis of cDNA identifies novel genes expressed following preconditioning of the heart

Fauchon MA, Pell TJ, Baxter GF, Yellon DM, Latchman D, Hubank MF, Mayn LV

  • KMID: 1093466
  • Exp Mol Med.
  • 2005 Aug;37(4):311-322.
Preconditioning of the myocardium rapidly induces a number of transcription factors, which are likely to be responsible for a cascade of transcriptional changes underlying the development of delayed adaptation. Identifying...
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Expression of MAGE-1, -2, and -3 genes in gastric carcinomas and cancer cell lines derived from Korean patients

Kim YM, Lee YH, Shin SH, Kim EH, Choi YW, Lee KM, Park JH, Lee YU, Seel DJ, Kim MC

We investigated the expression of MAGE-1, -2, and -3 genes in tissues of 51 gastric carcinomas from Korean patients and in 11 gastric cancer cell lines established in Korea using...
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Regulation of type I collagen and interstitial collagenase mRNA expression in human dermal fibroblasts by colchicine and D-penicillamine

Chung KY, Kang DS

Sclerosis is a disease process in which idiopathic hardening occurs in the skin and/or internal organs as a result of the accumulation of type I collagen, induced mainly by transforming...
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