- A Melting Method for RNA Extraction from the Mucosal Membrane of the Mouse Middle Ear
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Seo YJ, Kim SH, Moon IS, Choi JY
- KMID: 2070030
- Yonsei Med J.
- 2015 Mar;56(2):497-502.
- doi: 10.3349/ymj.2015.56.2.497
PURPOSE: There is much confusion surrounding the methods of RNA extraction from the middle ear mucosa of mice. In this study, we worked to develop a "melting method," which is... -
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- Hsp70 Knockdown by siRNA Decreased Collagen Production in Keloid Fibroblasts
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Shin JU, Lee WJ, Tran TN, Jung I, Lee JH
- KMID: 2345891
- Yonsei Med J.
- 2015 Nov;56(6):1619-1626.
- doi: 10.3349/ymj.2015.56.6.1619
PURPOSE: There are currently no consistently effective treatments for the excessive collagen produced by keloid fibroblasts. Previously, we reported that heat shock protein 70 (Hsp70) is up-regulated in keloid fibroblasts... -
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- miR-526b targets 3' UTR of MMP1 mRNA
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Kim KH, Jung JY, Son ED, Shin DW, Noh M, Lee TR
- KMID: 2155432
- Exp Mol Med.
- 2015 Aug;47(8):e178.
- doi: 10.1038/emm.2015.52
Regulation of matrix metalloproteinases (MMPs) is important for many physiological processes involving cancers, inflammation, tissue remodeling and skin aging. Here, we report the novel finding that the expression of MMP1... -
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- mRNA Expression and RNA Editing (2451 C-to-U) of IL-12 Receptor beta2 in Adult Atopic Patients
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Kim EJ, Lee WM, Ha JS, Ryoo NH, Jeon DS, Kim JR
- KMID: 1713121
- J Korean Med Sci.
- 2006 Dec;21(6):1070-1074.
- doi: 10.3346/jkms.2006.21.6.1070
Interleukin (IL)-12 activates T helper (Th) 1 cells to produce interferon (IFN)-gamma which inhibits atopic inflammation. IL-12 acts through interaction with its receptor, especially beta2 subunit. In several studies, the... -
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- Characterization of an unusual variant mRNA of human lysosomal alpha-mannosidase
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Sun H, Wolfe JH
- KMID: 755097
- Exp Mol Med.
- 2000 Dec;32(4):187-192.
Lysosomal alpha-mannosidase (EC 3.2.1.24) is an exoglycosidase in the glycoprotein degradation pathway and is encoded by a 3.0 kb cDNA. A 2.3 kb cDNA from a minor species... -
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- Apolipoproteins as Differentiating and Predictive Markers for Assessing Clinical Outcomes in Patients with Small Cell Lung Cancer
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Shi J, Yang H, Duan X, Li L, Sun L, Li Q, Zhang J
- KMID: 2374071
- Yonsei Med J.
- 2016 May;57(3):549-556.
- doi: 10.3349/ymj.2016.57.3.549
PURPOSE: The present study aimed to investigate the value of apolipoproteins, including ApoA-1, ApoC-III, and ApoE, in patients with small cell lung cancer (SCLC) as potential biomarkers for diagnosis, prognosis,... -
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- The Protective Effect of Sodium Hyaluronate on the Cartilage of Rabbit Osteoarthritis by Inhibiting Peroxisome Proliferator-Activated Receptor-Gamma Messenger RNA Expression
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Zhou JL, Liu SQ, Qiu B, Hu QJ, Ming JH, Peng H
- KMID: 1777099
- Yonsei Med J.
- 2009 Dec;50(6):832-837.
- doi: 10.3349/ymj.2009.50.6.832
PURPOSE: The purpose of this study was to study the protective effect and influence of sodium hyaluronate (Na-HA) on mRNA expression of peroxisome proliferators-activated receptor gamma (PPAR-gamma) in cartilage of... -
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- Change of the Expression of Human Telomerase Reverse Transcriptase mRNA and Human Telomerase RNA after Cisplatin and 5-Fluorouracil Exposure in Head and Neck Squamous Cell Carcinoma Cell Lines
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Lee BJ, Lee BH, Wang SG, Lee JC, Roh HJ, Goh EK, Kim CM, Jun ES
- KMID: 1785792
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S73-S78.
- doi: 10.3346/jkms.2007.22.S.S73
Telomerase activity appears to be associated with cell immortalization and malignant progression. Understanding how telomerase activity is regulated in vivo is important not only for understanding the molecular biology of... -
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- Tunicamycin-induced Endoplasmic Reticulum Stress Upregulates the Expression of Pentraxin 3 in Human Retinal Pigment Epithelial Cells
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Hwang N, Kwon MY, Cha JB, Chung SW, Woo JM
- KMID: 2374005
- Korean J Ophthalmol.
- 2016 Dec;30(6):468-478.
- doi: 10.3341/kjo.2016.30.6.468
PURPOSE: To investigate the production of long pentraxin 3 (PTX3) in response to tunicamycin-induced endoplasmic reticulum (ER) stress and its role in ER stress-associated cell death, PTX3 expression was evaluated... -
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- IL28B Is Associated with Outcomes of Chronic HBV Infection
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Shi X, Chi X, Pan Y, Gao Y, Li W, Yang C, Zhong J, Xu D, Zhang M, Minuk G, Jiang J, Niu J
- KMID: 2450334
- Yonsei Med J.
- 2015 May;56(3):625-633.
- doi: 10.3349/ymj.2015.56.3.625
PURPOSE: The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are... -
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- Comprehensive analysis of microRNA-mRNA co-expression in circadian rhythm
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Na YJ, Sung JH, Lee SC, Lee YJ, Choi YJ, Park WY, Shin HS, Kim JH
- KMID: 756207
- Exp Mol Med.
- 2009 Sep;41(9):638-647.
- doi: 10.3858/emm.2009.41.9.070
To investigate the potential role of microRNA (miRNA) in the regulation of circadian rhythm, we performed microarray-based expression profiling study of both miRNA and mRNA in mouse liver for 48... -
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- Induction of PPAR Gamma mRNA and Protein Expression by Rosiglitazone in Chronic Cyclosporine Nephropathy in the Rat
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Ahn KO, Lim SW, Yang HJ, Li C, Sugawara A, Ito S, Choi BS, Kim YS, Kim J, Yang CW
- KMID: 1779536
- Yonsei Med J.
- 2007 Apr;48(2):308-316.
- doi: 10.3349/ymj.2007.48.2.308
PURPOSE: We recently reported that rosiglitazone (RGTZ), a peroxisome proliferator-activated receptor gamma (PPARgamma) agonist, has a protective effect against cyclosporine (CsA)- induced renal injury. Here we report the effect of... -
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- Phosphatidylinositol 4-phosphate 5-kinase alpha is induced in ganglioside-stimulated brain astrocytes and contributes to inflammatory responses
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Lee SY, Kim B, Yoon S, Kim YJ, Liu T, Woo JH, Chwae YJ, Joe EH, Jou I
- KMID: 983958
- Exp Mol Med.
- 2010 Sep;42(9):662-673.
- doi: 10.3858/emm.2010.42.9.066
In brain tissue, astrocytes play defensive roles in central nervous system integrity by mediating immune responses against pathological conditions. Type I phosphatidylinositol 4-phosphate 5-kinase alpha (PIP5Kalpha) that is responsible for... -
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