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Effect of growth factors on the expression of proto-oncogenes c-fos and c-myc in FRTL-5 cell line

Yoon HY, Oh SK, Yi KH, Cho BY, Koh CS

This study was performed to prove the hypothesis that oncogene expressions would have the same patterns with those of cellular growth to growth factors in FRTL-5 cells. Ribonucleic acids of...
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Neuroimmunological Activation of Afferent Auditory Neural Circuit in LPS-Induced Otitis Media

Jun BC, Kim HT, Song CE, Lee DH, Yeo SW

  • KMID: 1977287
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Oct;49(10):978-985.
BACKGROUND AND OBJECTIVES : The goal of this study was to identify the central modulation of the auditory pathway by peripheral inflammation and loud sound exposure, which is associated with...
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Catechins inhibit angiotensin II-induced vascular smooth muscle cell proliferation via mitogen-activated protein kinase pathway

Won SM, Park YH, Kim HJ, Park KM, Lee WJ

  • KMID: 1098087
  • Exp Mol Med.
  • 2006 Oct;38(5):525-534.
Catechins, components of green tea, reduce the incidence of cardiovascular diseases such as atherosclerosis. Angiotensin II (Ang II) is highly implicated in the proliferation of vascular smooth muscle cells (VSMC),...
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Black rice anthocyanidins prevent retinal photochemical damage via involvement of the AP-1/NF-kappaB/Caspase-1 pathway in Sprague-Dawley Rats

Jia H, Chen W, Yu X, Wu X, Li S, Liu H, Liao J, Liu W, Mi M, Liu L, Cheng D

The effects of black rice anthocyanidins (BRACs) on retinal damage induced by photochemical stress are not well known. In the present study, Sprague-Dawley rats were fed AIN-93M for 1 week,...
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The Subdivision of the Spinal Neurons for Detrusor Function

Jeon HJ, Lee HY, Noh JY, Hong CH, Kim JH, Han SW

  • KMID: 2293972
  • Korean J Urol.
  • 2005 May;46(5):487-494.
Purpose: No ideal method for subdividing and assessing changes in neurons of the spinal cord during specific conditions has been established. We attempted to develop a method for subdividing spinal...
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Studies on the Vestibular Compensation after Contralateral Labyrinthectomy in Unilateral Labyrinthectomized Rats

Kim JY, Kim JK, Kim KT, Park SY, Chun KD, Lee MY, Park BR

  • KMID: 1873949
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 Oct;41(10):1241-1247.
BACKGROUND AND OBJECTIVES: Vestibular compensation is a process of behavioral recovery following unilateral labyrinthectomy (ULX). The neural plasticity in vestibular compensation was assessed by observing changes of behavioral response and...
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The Effects of Essential Aroma Oils on Brain Activation: Olfactory Functional MRI and c-Fos Expression

Ye MK, Shin SH, Park KP, Lee SH, Cho TH, Lee JE, Chang YM, Jeong OR

  • KMID: 2037140
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 May;46(5):401-408.
BACKGROUND AND OBJECTIVES: For centuries, fragrance had beneficial psychological and physiological effects on humans. Aromatherapy, the use of concentrated essential oils extracted from herbs, flowers, and other parts of plants...
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Regulation of phosphorylated cAMP response element-binding protein, Fos-related antigen and FosB expression by dopamine agonists in rat striatum

Choe ES, Kim JY

  • KMID: 2071569
  • Korean J Physiol Pharmacol.
  • 2001 Aug;5(4):299-305.
Activation of D1-like dopamine receptors by psychostimulants, such as amphetamine, upregulates the expression of immediate early gene and opioid peptide gene in the striatum. The genomic changes are regulated by phosphorylated transcription factors...
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Transcriptional regulation of Zic3 by heterodimeric AP-1(c-Jun/c-Fos) during Xenopus development

Lee SY, Lee HS, Moon JS, Kim JI, Park JB, Lee JY, Park MJ, Kim J

  • KMID: 1123768
  • Exp Mol Med.
  • 2004 Oct;36(5):468-475.
The heterodimeric c-Jun/c-Fos, an activator protein-1 (AP-1) has been implicated in mesoderm induction (Dong et al., 1996; Kim et al., 1998) whereas the homodimer of c-Jun was reported to be...
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Intragastric gavage with denatonium benzoate acutely induces neuronal activation in the solitary tract nucleus via the vagal afferent pathway

Jung HY, Kim W, Yoo DY, Nam SM, Kim JW, Choi JH, Yoon YS, Kim HY, Hwang IK

Natural toxic substances have a bitter taste and their ingestion sends signals to the brain leading to aversive oral sensations. In the present study, we investigated chronological changes in c-Fos...
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Relationships Among Factors Relevant to Abdominal Fat and Age-Related Hearing Loss

Lee Y, Park M

OBJECTIVES: Metabolic syndrome is related with abdominal fat and with age-related hearing loss (ARHL). In this study, we evaluated the association between a variety of factors relevant to abdominal fat...
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Morphometric Study of the Effects of Various Analgesic Compound in Experimental Arthritis Model

Ahn SK, Lee JE, Baik JS, Kim HJ, Lee WT, Park KA

  • KMID: 1558774
  • Korean J Anat.
  • 2001 Dec;34(6):653-666.
Arthritis is the most common disease of joint in old age and almost all the old human are suffering from arthritis. Arthritis gives so severe pain hard to endure that...
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Central N omega-nitro-L-arginine Methyl Ester Does not Influence Lithium-induced c-Fos and Conditioned Taste Aversion

Jahng JW, Choi SH, Kim DG, Houpt TA

  • KMID: 2428356
  • Yonsei Med J.
  • 2003 Oct;44(5):869-874.
LiCl at doses sufficient to induce conditioned taste aversion (CTA) causes c-Fos expression in the brain regions implicated in CTA formation. It has been reported that nitric oxide (NO) may...
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Effects of DA-9701, a Novel Prokinetic Agent, on Phosphorylated Extracellular Signal-Regulated Kinase Expression in the Dorsal Root Ganglion and Spinal Cord Induced by Colorectal Distension in Rats

Lee SP, Lee KN, Lee OY, Lee HL, Jun DW, Yoon BC, Choi HS, Hwang SJ, Lee SE

  • KMID: 1774540
  • Gut Liver.
  • 2014 Mar;8(2):140-147.
BACKGROUND/AIMS: DA-9701, a standardized extract of Pharbitis Semen and Corydalis Tuber, is a new prokinetic agent that exhibits an analgesic effect on the abdomen. We investigated whether DA-9701 affects visceral...
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c-Fos Immunoreactivity in the Neurons of the Lateral Geniculate Nucleus in Albino Rats by Light Exposure after Dark Rearing

Cha YJ, Lee JH, Baik TK, Park JS

PURPOSE: To investigate the effect of dark rearing immediately after birth on the maturation of the visual relay neurons in the lateral geniculate nucleus. METHODS: Fifty neonatal rats were used. Neonates...
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c-fos Expression in Bladder-Specific Spinal Neurons after Spinal Cord Injury Using Pseudorabies Virus

Im YJ, Hong CH, Jin MH, Lee BH, Han SW

PURPOSE: c-fos expression in spinal neurons that are activated by lower urinary tract stimulation are not organ specific. In this experiment, we demonstrated changes of c-fos expression in bladder-specific preganglionic...
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CNS innervation of the urinary bladder demonstrated by immunohistochemical study for c-fos and pseudorabies virus

Park MJ, Kim JY, Bae YC, Son BW, Park YK, Lee BH, Cho KJ, Kim DY, Sung EG, Yoon YW

The aim of the present study is to verify the functional and anatomical neural pathways which innervate the urinary bladder in the central nervous system of the rat. To...
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Effects of MK-801 and Morphine on Spinal C-Fos Expression during the Development of Neuropathic Pain

Lee YW, Park KA, Lee WT

The purpose of this study was to investigate the expression of c-fos in the spinal cord during the development of allodynia, induced by peripheral nerve injury. Following tight ligation of...
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Studies on the changes of c-fos protein in spinal cord and neurotransmitter in dorsal root ganglion of the rat with an experimental peripheral neuropathy

Lee WT, Sohn MK, Park SH, Ahn SK, Lee JE, Park KA

Animal models for human chronic pain syndromes have been developed and widely used for pain research. One of these neuropathic pain models by Kim and Chung (1992)...
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Role of gamma-aminobutyric acid B (GABA B) receptors in the regulation of kainic acid-induced cell death in mouse hippocampus

Lee HK, Seo YJ, Choi SS, Kwon MS, Shim EJ, Lee JY, Suh HW

  • KMID: 1116198
  • Exp Mol Med.
  • 2005 Dec;37(6):533-545.
Kainic acid (KA) is well-known as an excitatory, neurotoxic substance. In mice, KA administered intracerebroventricularly (i.c.v.) lead to morphological damage of hippocampus expecially concentrated on the CA3 pyramidal neurons. In...
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