Clin Exp Otorhinolaryngol.  2017 Dec;10(4):309-314. 10.21053/ceo.2017.00017.

Relationships Among Factors Relevant to Abdominal Fat and Age-Related Hearing Loss

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea. pimpleboy@naver.com
  • 2Department of Translational Biomedical Research, Seoul National University College of Medicine, Seoul, Korea.

Abstract


OBJECTIVES
Metabolic syndrome is related with abdominal fat and with age-related hearing loss (ARHL). In this study, we evaluated the association between a variety of factors relevant to abdominal fat (FRAs) and hearing thresholds.
METHODS
We reviewed retrospectively the medical records of 2,602 subjects aged over 40 years with symmetrical sensorineural hearing loss who underwent abdominal fat computed tomography (CT) scans. Univariate and multivariate linear regression analyses were used to demonstrate the association between each FRA and hearing thresholds at low and high frequencies.
RESULTS
Four of 5 FRAs were associated with hearing thresholds at high frequencies in males. All FRAs examined showed a relationship with hearing thresholds at low frequencies in females. Diabetes mellitus (DM) among clinical factors and visceral adipose tissue (VAT) among the 5 FRAs were the most reflective of hearing thresholds in both males and females.
CONCLUSION
We found that FRAs were associated with hearing loss with frequency specific characteristics according to sex and reinforced that DM and VAT is particularly an important role for hearing.

Keyword

Hearing Loss; Abdominal Fat; Visceral Fat; Body Mass Index

MeSH Terms

Abdominal Fat*
Body Mass Index
Diabetes Mellitus
Female
Hearing Loss*
Hearing Loss, Sensorineural
Hearing*
Humans
Intra-Abdominal Fat
Linear Models
Male
Medical Records
Proto-Oncogene Proteins c-fos
Retrospective Studies
Proto-Oncogene Proteins c-fos

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