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Analysis of Treatment Pattern in COPD Patients Using Health Insurance Claims Data: Focusing on Inhaled Medications

Lim H, Park M

Background: Chronic obstructive pulmonary disease (COPD) is not completely reversible and requires long-term management with appropriate treatment. This study aimed to analyze trends in treatment regimens and medication costs for...
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Inhibition of voltage-dependent K+ channels by antimuscarinic drug fesoterodine in coronary arterial smooth muscle cells

Park S, Kang M, Heo R, Mun SY, Park M, Han ET, Han JH, Chun W, Park H, Park WS

Fesoterodine, an antimuscarinic drug, is widely used to treat overactive bladder syndrome. However, there is little information about its effects on vascular K+ channels. In this study, voltage-dependent K+ (Kv)...
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Inhibitory effects of the atypical antipsychotic, clozapine, on voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells

Kang M, Heo R, Park S, Mun SY, Park M, Han ET, Han JH, Chun W, Ha KS, Park H, Jung WK, Choi IW, Park WS

To investigate the adverse effects of clozapine on cardiovascular ion channels, we examined the inhibitory effect of clozapine on voltage-dependent K+(Kv) channels in rabbit coronary arterial smooth muscle cells. Clozapine-induced...
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Effectiveness of Devices for Prevention and Treatment of Pressure Ulcers: A scoping Review

Jung SY, Park M, Moon KJ

Purpose: Pressure ulcers (PUs) are a common problem affecting the quality of life of patients and also hindering the quality of medical services. The purpose of this scoping review was...
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Effectiveness and Safety of Regdanvimab in Patients With Mild-ToModerate COVID-19: A Retrospective Cohort Study

Park S, Je NK, Kim DW, Park M, Heo J

Background: Regdanvimab has decreased the time to clinical recovery from coronavirus disease 2019 (COVID-19) and lowered the rate of oxygen therapy according to the results from phase 2/3 randomized controlled...
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In silico screening method for non‑responders to cardiac resynchronization therapy in patients with heart failure: a pilot study

Hwang M, Uhm J, Park M, Shim E, Lee C, Oh J, Yu H, Kim T, Joung B, Pak H, Kang S, Lee M

Background: Cardiac resynchronization therapy (CRT) is an effective treatment option for patients with heart failure (HF) and left ventricular (LV) dyssynchrony. However, the problem of some patients not responding to CRT...
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Expectation of Medical Personnel for the Roles of the Physician Assistants in a University Hospital

Ryu MJ, Park M, Shim J, Lee E, Yeom I, Seo YM

Purpose: The purpose of this study is to clearly classify the roles of Physician assistants and to identify obstacle factors and necessary factors for the operation of the system when...
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Response to Neoadjuvant Therapy and Prognosis in Patients with Resectable Pancreatic Cancer: A Propensity Score Matching Analysis

Yoon MS, Lee HS, Kang CM, Lee WJ, Keum J, Sung MJ, Kim S, Park M, Jo JH, Chung MJ, Park JY, Park SW, Song SY, Hwang HK, Bang S

Background/Aims: Controversy regarding the effectiveness of neoadjuvant therapy for resectable pancreatic ductal adenocarcinoma (PDAC) still exists. Here, we aimed to identify the potential benefits of neoadjuvant therapy followed by surgery...
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Effect of Infection Control Education Based on Isolation Room-Simulation for Nursing Students

Jang I, Park M

Purpose: This study aimed to analyze the effects of infection control education (ICE) prospectively, based on isolation room simulation for nursing college students. Methods: From September 21 to 30 2020,...
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Fabrication of complete denture by stereolithography-based 3D printing: a case report

Yun Y, Park M, Park S, Park C, Jang W, Lee SK

The conventional complete denture has disadvantages such as multiple visits to the dental clinic, including definitive impression and intermaxillary relationship records after taking preliminary impressions and making individual trays and...
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The development of patient-controlled sedation pump for minor surgical procedures

Kang H, Lee E, Bae I, Park M, Son Y, Kim Y

Patient-controlled sedation systems, in which the patient has control of sedative administration, have been shown to be effective and safe for patients undergoing minor procedures. Safety depends on the adequacy...
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An experience on the model-based evaluation of pharmacokinetic drug-drug interaction for a long half-life drug

Hong Y, Jeon S, Choi S, Han S, Park M, Han S

Fixed-dose combinations development requires pharmacokinetic drugdrug interaction (DDI) studies between active ingredients. For some drugs, pharmacokinetic properties such as long half-life or delayed distribution, make it difficult to conduct such...
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Implant overdenture with closed impression technique for patient with Myasthenia Gravis: A case report

Park L, Park M, Park S, Lim HP, Jang W

In patients with myasthenia gravis, it is difficult to manufacture and maintain dentures because the muscles and nervous system in the oral cavity are not properly adjusted. In addition, excessively...
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Changes in allergen sensitization in children with allergic diseases in the 1980 to 2019

Jung JH, Kim GE, Park M, Kim SY, Kim MJ, Lee YJ, Kim YH, Kim KW, Sohn MH

Purpose: Allergen sensitization is constantly changing, and understanding these changes can help manage and prevent allergic diseases. This research analyzed and compared the changes in allergen sensitization in children diagnosed...
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Economic change and graft outcome in kidney transplant recipients: a nationwide study of Korea

Park S, Park J, Kang EJ, Kim Y, Kim YC, Kim YS, Park M, Lee H

Background: The socioeconomic status of kidney transplant (KT) recipients is closely associated with graft prognosis. Further study is warranted to investigate whether changes in socioeconomic status occur after KT alongside...
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Toll‐Like Receptor 7 (TLR7) Mediated Transcriptomic Changes on Human Mast Cells

Cho KA, Choi DW, Park M, Kim YH, Woo SY

Background: Mast cells are skin immune sentinels located in the upper dermis, where wheal formation and sensory nerve stimulation take place. Skin inflammation is occasionally accompanied by mast cell-driven responses...
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Nasal packing with bupivacaine during nasotracheal intubation can reduce intubation-related epistaxis

Yu HK, Park J, Kang YH, Park HB, Bae SI, Lee SH, Ok SH, Jeong SH, Park M

Epistaxis often is caused by nasal mucosal damage and vascular injury after nasotracheal (NT) intubation. Bupivacaine constricts blood vessels at low concentrations and dilates them at high concentrations. In this...
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Factors Influencing Health-related Quality of Life according to Sitting-time of Elders Living Alone: Data from the 7th Korea National Health and Nutrition Examination Survey (2016~2018)

Kwon M, Kim SA, Kim JI, Park M

Purpose: The purpose of this study was to identify factors influencing health-related quality of life depending on time sitting by elders living alone. Methods: This was a secondary data analysis study...
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Significant Shortening of Leukocyte Telomere Length in Korean Patients with Bipolar Disorder 1

Joo EJ, Ahn YM, Park M, Kim SA

Objective: Telomere shortening has been seen in major psychiatric disorders, including major depressive disorder. However, only a few small studies have examined this in bipolar disorder (BD). We compared the telomere...
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Two Cases of Idiopathic Progressive Sensorineural Hearing Loss with Positional Nystagmus in Postpartum Period: Possible Spontaneous Perilymph Fistula?

Park M, Kim HJ, Chung WH

Perilymph fistula (PLF) is defined as an abnormal communication between the middle ear cavity and perilymphatic space of the inner ear. Most cases of PLF are responsible for pressure change...
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