- Studies on the protein biosynthesis in isolated periodontal ligament
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Chung HI
- KMID: 2271422
- Korean J Orthod.
- 1979 Dec;9(1):9-14.
The purpose of this study was to pursue the biosynthesis of proteins of human and bovine periodontal ligaments in vitro system. The excised periodontal ligaments from human and bovine were... -
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- The effect of tensile force on dna and protein synthesis in bone cells
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Kwon OS, Kim SC
- KMID: 1977087
- Korean J Orthod.
- 1994 Dec;24(4):933-943.
The present study was undertaken to determine the effect of tensile force on DNA and protein biosynthesis in bone cells, and to identify the cell type(s) which primarily respond to... -
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- Neuronal activation increases the density of eukaryotic translation initiation factor 4E mRNA clusters in dendrites of cultured hippocampal neurons
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Moon IS, Cho SJ, Seog DH, Walikonis
- KMID: 1119326
- Exp Mol Med.
- 2009 Aug;41(8):601-610.
- doi: 10.3858/emm.2009.41.8.066
Activity-dependent dendritic translation in CNS neurons is important for the synapse-specific provision of proteins that may be necessary for strengthening of synaptic connections. A major rate-limiting factor during protein synthesis... -
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- Formation of Airway Mucus; Synthesis, Exocytosis and Dilution of Gel-Forming Mucins
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- KMID: 1969528
- Korean J Asthma Allergy Clin Immunol.
- 2012 Jun;32(2):73-80.
The lungs are highly defensive to environmental challenges thanks to the airway mucus layer, not only as a pool of antimicrobial and antioxidant contents but also as an important part... -
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- An Emerging Role for Circular RNAs in Osteoarthritis
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Yu CX, Sun S
- KMID: 2407857
- Yonsei Med J.
- 2018 May;59(3):349-355.
- doi: 10.3349/ymj.2018.59.3.349
Circular RNAs (circRNAs) are currently classed as non-coding RNAs that, unlike the better known canonical linear RNAs, form a covalently closed continuous loop without 5′ or 3′ polarities. With the... -
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- The translation inhibitor anisomycin induces Elk-1-mediated transcriptional activation of egr-1 through multiple mitogen-activated protein kinase pathways
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Shin SY, Lee JH, Min B, Lee YH
- KMID: 1115946
- Exp Mol Med.
- 2006 Dec;38(6):677-685.
The early growth response-1 gene (egr-1) encodes a zinc-finger transcription factor Egr-1 and is rapidly inducible by a variety of extracellular stimuli. Anisomycin (ANX), a protein synthesis inhibitor, stimulates mitogen-activated... -
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- Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells
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Moon SH, Kim HW, Kim JS, Park JH, Kim H, Eu GJ, Cho HS, Kang GM, Lee KH, Cho MH
- KMID: 1093633
- J Vet Sci.
- 2004 Dec;5(4):369-378.
Evidences show that eukaryotic mRNAs can perform protein translation through internal ribosome entry sites (IRES). 5'-Untranslated region of the mRNA encoding apoptotic protease-activating factor 1 (Apaf-1) contains IRES, and, thus,... -
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- Inhibition of MMP-13 mRNA expression by ginseng saponin in fetal rat calvarial cells
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Kim YY, Ciu DZ, Kim YJ
- KMID: 1999757
- J Korean Acad Periodontol.
- 2005 Jun;35(2):277-288.
- doi: 10.5051/jkape.2005.35.2.277
There is a potential role of collagenase-3 in alveolar bone loss and periodontal disease progression, we need to develope or find chemotherapeutic drugs or herbal agents which may regulate the... -
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- Enrichment of Low Abundance Proteins of Helicobacter pylori Strain 26695 by the Heparin Chromatography
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Lee WK, Kim MH, Song JY, Kim SC, Park JU, Baik SC, Kang HL, Park SG, Hwang HR, Bae DW, Youn HS, Ko GH, Cho MJ, Rhee KH
- KMID: 1579118
- J Bacteriol Virol.
- 2004 Dec;34(4):261-272.
Low-abundance cellular proteins normally invisible on the standard two-dimensional SDS-polyacrylamide gel electrophoresis (2-DE SDS-PAGE) map must be enriched appropriately in order to be visualized and identified in cells or tissues.... -
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- Expression of Phosphorylated ERK1/2 and cFos Proteins in Vestibular Nuclei by Selective Stimulation of Horizontal Semicircular Canal
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Choi BK, Lee YJ, Lee HS, Park SW, Park HY, Jang H, Kim YS, Jo KH, Choi MA, Lee JH, Kim MS, Park BR
- KMID: 2343149
- J Korean Neurol Assoc.
- 2005 Apr;23(2):257-263.
BACKGROUND: There is a little information about the effect of selective vestibular stimulation on the expression of activity-dependent metabolic markers in the vestibular nuclei. The purpose of this study was... -
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- Pleckstrin homology domain of phospholipase C-gamma1 directly binds to 68-kDa neurofilament light chain
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Kim SK, Choi JH, Suh PG, Chang JS
- KMID: 1094152
- Exp Mol Med.
- 2006 Jun;38(3):265-272.
Phosphoinositide-specific phospholipase C-gamma1 (PLC-gamma1) has two pleckstrin homology (PH) domains: an amino-terminal domain (PH1) and a split PH domain (PH2). Here, we show that overlay assay of bovine brain tubulin... -
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- MT1-MMP and Egr-1 Expressions Induced by Different Strengths of Shear Stress in Endothelial Cell
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Yun SS, Jeon SY, Park JK, Lee S, Choi SH, Koh YB
- KMID: 1941115
- J Korean Soc Vasc Surg.
- 2003 May;19(1):5-12.
PURPOSE: Membrane type-1-matrix metalloproteinase (MT1-MMP) plays a key role in endothelial cell (EC) migration, matrix remodeling, and angiogenesis. Previous studies demonstrated that a cyclic strain (CS) increases MT1-MMP expression by... -
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- Induction of PPAR Gamma mRNA and Protein Expression by Rosiglitazone in Chronic Cyclosporine Nephropathy in the Rat
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Ahn KO, Lim SW, Yang HJ, Li C, Sugawara A, Ito S, Choi BS, Kim YS, Kim J, Yang CW
- KMID: 1779536
- Yonsei Med J.
- 2007 Apr;48(2):308-316.
- doi: 10.3349/ymj.2007.48.2.308
PURPOSE: We recently reported that rosiglitazone (RGTZ), a peroxisome proliferator-activated receptor gamma (PPARgamma) agonist, has a protective effect against cyclosporine (CsA)- induced renal injury. Here we report the effect of... -
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- Janus Kinase 2 Inhibitor AG490 Inhibits the STAT3 Signaling Pathway by Suppressing Protein Translation of gp130
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Seo IA, Lee HK, Shin YK, Lee SH, Seo SY, Park JW, Park HT
- KMID: 2071662
- Korean J Physiol Pharmacol.
- 2009 Apr;13(2):131-138.
- doi: 10.4196/kjpp.2009.13.2.131
The binding of interleukin-6 (IL-6) cytokine family ligands to the gp130 receptor complex activates the Janus kinase (JAK)/ signal transducer and activator of transcription 3 (STAT3) signal transduction pathway,... -
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- Overexpression of USF Increases TGF-beta1 Protein Levels, But G1 Phase Arrest was not Induced in FRTL-5 Cells
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Kim KS, Jung HS, Chung YJ, Jung TS, Jang HW, Lee MS, Kim KW, Chung JH
- KMID: 1783075
- J Korean Med Sci.
- 2008 Oct;23(5):870-876.
- doi: 10.3346/jkms.2008.23.5.870
Transforming growth factor-beta1 (TGF-beta1) is a potent inhibitor of cellular growth and proliferation by G1 phase arrest or apoptosis. We investigated the association of TGF-beta1 with the anti-proliferative effect of... -
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- Translational Regulation: A Novel Target for Breast Cancer Therapy
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Noh WC, Paik NS
- KMID: 1906252
- J Korean Breast Cancer Soc.
- 2003 Mar;6(1):8-14.
- doi: 10.4048/jkbcs.2003.6.1.8
Translational initiation is regulated in response to nutrient availabilty and growth stimuli and is coupled with cell cycle progression and cell growth. There is now growing body of evidence which... -
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- Cell type-specific upregulation of myristoylated alanine-rich C kinase substrate and protein kinase C-alpha, -beta I, -beta II, and -delta in microglia following kainic acid-induced seizures
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Eun SY, Kim EH, Kang KS, Kim HJ, Jo SA, Kim SJ, Jo SH, Kim SJ, Blackshear PJ, Kim J
- KMID: 1094157
- Exp Mol Med.
- 2006 Jun;38(3):310-319.
Myristoylated alanine-rich C kinase substrate (MARCKS) is a widely distributed protein kinase C (PKC) substrate and has been implicated in actin cytoskeletal rearrangement in response to extracellular stimuli. Although MARCKS... -
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- Transcription of class II MHC gene by interferon-gamma in FRTL-5 cells
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Lee MS, Lee JO, Kang TW, Lee JH
- KMID: 1421913
- J Korean Med Sci.
- 1992 Sep;7(3):189-192.
- doi: 10.3346/jkms.1992.7.3.189
The intracellular mechanism by which interferon-gamma induces the expression of class II major histocompatibility complex (MHC) antigen in nonlymphoid cells is not clear. The effect of recombinant rat interferon-gamma... -
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- cDNA Microarray Analysis of Gene Expression Profiles Associated with Cervical Cancer
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Yoon JH, Lee JM, Namkoong S, Bae SM, Kim YW, Han SJ, Cho YL, Nam GH, Kim CK, Seo JS, Ahn WS
- KMID: 2166164
- Cancer Res Treat.
- 2003 Oct;35(5):451-459.
PURPOSE: The molecular pathology of cervical cancers associated with human papillomavirus infection is presently unclear. In an effort to clarify this issue, the gene expression profiles and pathogenic cellular processes... -
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- MicroRNA-27 Promotes Odontoblast Differentiation via Wnt1 Signaling
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Cho JH, Kim SG, Park BS, Go DS, Park JC, Kim DK
- KMID: 2133224
- Int J Oral Biol.
- 2015 Dec;40(4):197-204.
- doi: 10.11620/IJOB.2015.40.4.197
MicroRNA (miRNA, miR) is essential in regulating cell differentiation either by inhibiting mRNA translation or by inducing its degradation. However, the role of miRNA in odontoblastic cell differentiation is still... -
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