- Studies on the protein biosynthesis in isolated periodontal ligament
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Chung HI
- KMID: 2271422
- Korean J Orthod.
- 1979 Dec;9(1):9-14.
The purpose of this study was to pursue the biosynthesis of proteins of human and bovine periodontal ligaments in vitro system. The excised periodontal ligaments from human and bovine were... -
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- The effect of tensile force on dna and protein synthesis in bone cells
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Kwon OS, Kim SC
- KMID: 1977087
- Korean J Orthod.
- 1994 Dec;24(4):933-943.
The present study was undertaken to determine the effect of tensile force on DNA and protein biosynthesis in bone cells, and to identify the cell type(s) which primarily respond to... -
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- Neuronal activation increases the density of eukaryotic translation initiation factor 4E mRNA clusters in dendrites of cultured hippocampal neurons
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Moon IS, Cho SJ, Seog DH, Walikonis
- KMID: 1119326
- Exp Mol Med.
- 2009 Aug;41(8):601-610.
- doi: 10.3858/emm.2009.41.8.066
Activity-dependent dendritic translation in CNS neurons is important for the synapse-specific provision of proteins that may be necessary for strengthening of synaptic connections. A major rate-limiting factor during protein synthesis... -
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- Formation of Airway Mucus; Synthesis, Exocytosis and Dilution of Gel-Forming Mucins
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- KMID: 1969528
- Korean J Asthma Allergy Clin Immunol.
- 2012 Jun;32(2):73-80.
The lungs are highly defensive to environmental challenges thanks to the airway mucus layer, not only as a pool of antimicrobial and antioxidant contents but also as an important part... -
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- An Emerging Role for Circular RNAs in Osteoarthritis
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Yu CX, Sun S
- KMID: 2407857
- Yonsei Med J.
- 2018 May;59(3):349-355.
- doi: 10.3349/ymj.2018.59.3.349
Circular RNAs (circRNAs) are currently classed as non-coding RNAs that, unlike the better known canonical linear RNAs, form a covalently closed continuous loop without 5′ or 3′ polarities. With the... -
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- The translation inhibitor anisomycin induces Elk-1-mediated transcriptional activation of egr-1 through multiple mitogen-activated protein kinase pathways
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Shin SY, Lee JH, Min B, Lee YH
- KMID: 1115946
- Exp Mol Med.
- 2006 Dec;38(6):677-685.
The early growth response-1 gene (egr-1) encodes a zinc-finger transcription factor Egr-1 and is rapidly inducible by a variety of extracellular stimuli. Anisomycin (ANX), a protein synthesis inhibitor, stimulates mitogen-activated... -
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- Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells
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Moon SH, Kim HW, Kim JS, Park JH, Kim H, Eu GJ, Cho HS, Kang GM, Lee KH, Cho MH
- KMID: 1093633
- J Vet Sci.
- 2004 Dec;5(4):369-378.
Evidences show that eukaryotic mRNAs can perform protein translation through internal ribosome entry sites (IRES). 5'-Untranslated region of the mRNA encoding apoptotic protease-activating factor 1 (Apaf-1) contains IRES, and, thus,... -
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- Inhibition of MMP-13 mRNA expression by ginseng saponin in fetal rat calvarial cells
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Kim YY, Ciu DZ, Kim YJ
- KMID: 1999757
- J Korean Acad Periodontol.
- 2005 Jun;35(2):277-288.
- doi: 10.5051/jkape.2005.35.2.277
There is a potential role of collagenase-3 in alveolar bone loss and periodontal disease progression, we need to develope or find chemotherapeutic drugs or herbal agents which may regulate the... -
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- Enrichment of Low Abundance Proteins of Helicobacter pylori Strain 26695 by the Heparin Chromatography
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Lee WK, Kim MH, Song JY, Kim SC, Park JU, Baik SC, Kang HL, Park SG, Hwang HR, Bae DW, Youn HS, Ko GH, Cho MJ, Rhee KH
- KMID: 1579118
- J Bacteriol Virol.
- 2004 Dec;34(4):261-272.
Low-abundance cellular proteins normally invisible on the standard two-dimensional SDS-polyacrylamide gel electrophoresis (2-DE SDS-PAGE) map must be enriched appropriately in order to be visualized and identified in cells or tissues.... -
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- Expression of Phosphorylated ERK1/2 and cFos Proteins in Vestibular Nuclei by Selective Stimulation of Horizontal Semicircular Canal
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Choi BK, Lee YJ, Lee HS, Park SW, Park HY, Jang H, Kim YS, Jo KH, Choi MA, Lee JH, Kim MS, Park BR
- KMID: 2343149
- J Korean Neurol Assoc.
- 2005 Apr;23(2):257-263.
BACKGROUND: There is a little information about the effect of selective vestibular stimulation on the expression of activity-dependent metabolic markers in the vestibular nuclei. The purpose of this study was... -
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- Pleckstrin homology domain of phospholipase C-gamma1 directly binds to 68-kDa neurofilament light chain
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Kim SK, Choi JH, Suh PG, Chang JS
- KMID: 1094152
- Exp Mol Med.
- 2006 Jun;38(3):265-272.
Phosphoinositide-specific phospholipase C-gamma1 (PLC-gamma1) has two pleckstrin homology (PH) domains: an amino-terminal domain (PH1) and a split PH domain (PH2). Here, we show that overlay assay of bovine brain tubulin... -
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- MT1-MMP and Egr-1 Expressions Induced by Different Strengths of Shear Stress in Endothelial Cell
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Yun SS, Jeon SY, Park JK, Lee S, Choi SH, Koh YB
- KMID: 1941115
- J Korean Soc Vasc Surg.
- 2003 May;19(1):5-12.
PURPOSE: Membrane type-1-matrix metalloproteinase (MT1-MMP) plays a key role in endothelial cell (EC) migration, matrix remodeling, and angiogenesis. Previous studies demonstrated that a cyclic strain (CS) increases MT1-MMP expression by... -
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- Induction of PPAR Gamma mRNA and Protein Expression by Rosiglitazone in Chronic Cyclosporine Nephropathy in the Rat
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Ahn KO, Lim SW, Yang HJ, Li C, Sugawara A, Ito S, Choi BS, Kim YS, Kim J, Yang CW
- KMID: 1779536
- Yonsei Med J.
- 2007 Apr;48(2):308-316.
- doi: 10.3349/ymj.2007.48.2.308
PURPOSE: We recently reported that rosiglitazone (RGTZ), a peroxisome proliferator-activated receptor gamma (PPARgamma) agonist, has a protective effect against cyclosporine (CsA)- induced renal injury. Here we report the effect of... -
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- Janus Kinase 2 Inhibitor AG490 Inhibits the STAT3 Signaling Pathway by Suppressing Protein Translation of gp130
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Seo IA, Lee HK, Shin YK, Lee SH, Seo SY, Park JW, Park HT
- KMID: 2071662
- Korean J Physiol Pharmacol.
- 2009 Apr;13(2):131-138.
- doi: 10.4196/kjpp.2009.13.2.131
The binding of interleukin-6 (IL-6) cytokine family ligands to the gp130 receptor complex activates the Janus kinase (JAK)/ signal transducer and activator of transcription 3 (STAT3) signal transduction pathway,... -
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- Overexpression of USF Increases TGF-beta1 Protein Levels, But G1 Phase Arrest was not Induced in FRTL-5 Cells
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Kim KS, Jung HS, Chung YJ, Jung TS, Jang HW, Lee MS, Kim KW, Chung JH
- KMID: 1783075
- J Korean Med Sci.
- 2008 Oct;23(5):870-876.
- doi: 10.3346/jkms.2008.23.5.870
Transforming growth factor-beta1 (TGF-beta1) is a potent inhibitor of cellular growth and proliferation by G1 phase arrest or apoptosis. We investigated the association of TGF-beta1 with the anti-proliferative effect of... -
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- Translational Regulation: A Novel Target for Breast Cancer Therapy
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Noh WC, Paik NS
- KMID: 1906252
- J Korean Breast Cancer Soc.
- 2003 Mar;6(1):8-14.
- doi: 10.4048/jkbcs.2003.6.1.8
Translational initiation is regulated in response to nutrient availabilty and growth stimuli and is coupled with cell cycle progression and cell growth. There is now growing body of evidence which... -
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- Cell type-specific upregulation of myristoylated alanine-rich C kinase substrate and protein kinase C-alpha, -beta I, -beta II, and -delta in microglia following kainic acid-induced seizures
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Eun SY, Kim EH, Kang KS, Kim HJ, Jo SA, Kim SJ, Jo SH, Kim SJ, Blackshear PJ, Kim J
- KMID: 1094157
- Exp Mol Med.
- 2006 Jun;38(3):310-319.
Myristoylated alanine-rich C kinase substrate (MARCKS) is a widely distributed protein kinase C (PKC) substrate and has been implicated in actin cytoskeletal rearrangement in response to extracellular stimuli. Although MARCKS... -
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- Transcription of class II MHC gene by interferon-gamma in FRTL-5 cells
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Lee MS, Lee JO, Kang TW, Lee JH
- KMID: 1421913
- J Korean Med Sci.
- 1992 Sep;7(3):189-192.
- doi: 10.3346/jkms.1992.7.3.189
The intracellular mechanism by which interferon-gamma induces the expression of class II major histocompatibility complex (MHC) antigen in nonlymphoid cells is not clear. The effect of recombinant rat interferon-gamma... -
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- cDNA Microarray Analysis of Gene Expression Profiles Associated with Cervical Cancer
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Yoon JH, Lee JM, Namkoong S, Bae SM, Kim YW, Han SJ, Cho YL, Nam GH, Kim CK, Seo JS, Ahn WS
- KMID: 2166164
- Cancer Res Treat.
- 2003 Oct;35(5):451-459.
PURPOSE: The molecular pathology of cervical cancers associated with human papillomavirus infection is presently unclear. In an effort to clarify this issue, the gene expression profiles and pathogenic cellular processes... -
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- Gene Expression Profiling of SH-SY5Y Human Neuroblastoma Cells Treated with Ginsenoside Rg1 and Rb1
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Lee JN, Yang BH, Choi SH, Kim SH, Chai YG, Jung KH, Lee JS, Choi KJ, Kim YS
- KMID: 2249021
- Korean J Biol Psychiatry.
- 2005 May;12(1):42-61.
OBJECTIVES: The ginsenoside Rg1 and Rb1, the major components of ginseng saponin, have neurotrophic and neuroprotective effects including promotion of neuronal survival and proliferation, facilitation of learning and memory, and... -
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