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3D architecture developments for spatial controls of periodontal ligament regeneration with angular orientations

Park CH

Various biomaterial-based, 3D architectures with micron-scaled geometries have been investigated for periodontal tissue neogenesis, and appropriate fabrication techniques for the scaffold manufacturing have been developed for pre-clinical or clinical situations....
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Periodontal healing using a collagen matrix with periodontal ligament progenitor cells in a dehiscence defect model in beagle dogs

Yoo SY, Lee JS, Cha JK, Kim SK, Kim CS

PURPOSE: To histologically characterize periodontal healing at 8 weeks in surgically created dehiscence defects in beagle dogs that received a collagen matrix with periodontal ligament (PDL) progenitor cells. METHODS: The bilateral...
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Helicobacter pylori inhibited cell proliferation in human periodontal ligament fibroblasts through the Cdc25C/CDK1/cyclinB1 signaling cascade

Li H, Liang D, Hu N, Dai X, He J, Zhuang H, Zhao W

PURPOSE: Several studies have shown that the oral cavity is a secondary location for Helicobacter pylori colonization and that H. pylori is associated with the severity of periodontitis. This study...
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Effects of four novel root-end filling materials on the viability of periodontal ligament fibroblasts

Akbulut MB, Arpaci PU, Eldeniz AU

OBJECTIVES: The aim of this in vitro study was to evaluate the biocompatibility of newly proposed root-end filling materials, Biodentine, Micro-Mega mineral trioxide aggregate (MM-MTA), polymethylmethacrylate (PMMA) bone cement, and...
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Comparison of Gene Expression from Supernumerary Dental Pulp and Periodontal Ligament Stem Cells

Lee S, Kim J, Kim J

The purpose of this study is to compare the properties of dental pulp and periodontal ligament stem cells from extracted supernumerary teeth by quantitative real-time PCR. Impacted supernumerary teeth in the...
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Regulation of Inflammatory Response in Periodontal Ligament Cells by Transglutaminase 2

Lee SY, Jang CH, Ryu JH

Transglutaminase2 (TGM2) is a multi-functional calcium dependent enzyme that affects angiogenesis, apoptosis, differentiation, attachment, and changes in the extracellular matrix. However, its function in periodontal tissue has not yet been...
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Evaluation of the periodontal regenerative properties of patterned human periodontal ligament stem cell sheets

Kim JH, Ko SY, Lee JH, Kim DH, Yun JH

PURPOSE: The aim of this study was to determine the effects of patterned human periodontal ligament stem cell (hPDLSC) sheets fabricated using a thermoresponsive substratum. METHODS: In this study, we fabricated...
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Static magnetic fields promote osteoblastic/cementoblastic differentiation in osteoblasts, cementoblasts, and periodontal ligament cells

Kim EC, Park J, Kwon IK, Lee SW, Park SJ, Ahn SJ

PURPOSE: Although static magnetic fields (SMFs) have been used in dental prostheses and osseointegrated implants, their biological effects on osteoblastic and cementoblastic differentiation in cells involved in periodontal regeneration remain...
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Optimizing the reconstruction filter in cone-beam CT to improve periodontal ligament space visualization: An in vitro study

Houno Y, Hishikawa , Gotoh KI, Naitoh M, Mitani A, Noguchi T, Ariji E, Kodera Y

PURPOSE: Evaluation of alveolar bone is important in the diagnosis of dental diseases. The periodontal ligament space is difficult to clearly depict in cone-beam computed tomography images because the reconstruction...
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Valproic Acid Modulates the Multipotency in Periodontal Ligament Stem Cells via p53-Mediated Cell Cycle

Um S, Lee H, Zhang Q, Kim HY, Lee JH, Seo BM

Human periodontal ligament stem cells (PDLSCs), a type of mesenchymal stem cell, are a promising source for dental regeneration and are identified in human periodontal ligaments from extracted third molars....
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Review of common conditions associated with periodontal ligament widening

Mortazavi , Baharvand

PURPOSE: The aim of this article is to review a group of lesions associated with periodontal ligament (PDL) widening. MATERIALS AND METHODS: An electronic search was performed using specialized databases such...
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The influence of root surface distance to alveolar bone and periodontal ligament on periodontal wound healing

Montevecchi M, Parrilli A, Fini M, Gatto MR, Muttini A, Checchi L

PURPOSE: The purpose of this animal study was to perform a 3-dimensional micro-computed tomography (micro-CT) analysis in order to investigate the influence of root surface distance to the alveolar bone...
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Effects of enamel matrix derivatives on the proliferation and the release of growth factors of human periodontal ligament cells

Jung GU, Pang EK

PURPOSE: Stimulating the proliferation and migration of periodontal ligament cells (PDLCs) has become the main goal of periodontal regeneration. To accomplish this goal, regeneration procedures have been developed, but results...
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Evaluation of the Viability of Rat Periodontal Ligament Cells after Storing at 0℃/2 MPa Condition up to One Week: In Vivo MTT Method

Jang SM, Cho SY, Kim ES, Jung IY, Lee SJ

PURPOSE: The aim of this study was to evaluate the rat periodontal ligament cell viability under 0℃/2 MPa condition up to one week using in vivo 3-(4,5-dimethylthiazol-2-y1)-2,5-diphenyltetrazolium bromide (MTT) assay. MATERIALS...
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Effects of Slow Programmable Cryopreservation on Preserving Viability of the Cultured Periodontal Ligament Cells from Human Impacted Third Molar

Kim JW, Kim TY, Kim YM, Pang EK, Kim SJ

PURPOSE: This study was conducted to determine cell viability and differentiation capability of human periodontal ligament (PDL) cells and to elucidate the effects of cryopreservation on the activity of human...
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Effect of fibroblast growth factor on injured periodontal ligament and cementum after tooth replantation in dogs

Yu SJ, Lee JS, Jung UW, Park JC, Kim BO, Choi SH

PURPOSE: The purpose of this animal study was to perform a histological and histomorphometric analysis in order to elucidate the effect of fibroblast growth factor-2 (FGF-2) on injured periodontal ligament...
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Antioxidant Effect of Eugenol in Human Periodontal Ligament Fibroblasts

Kim YH, Park BS

Periodontal disease (PD) is the most common osteolytic disease of alveolar bone, oral infection seen in humans worldwide. PD is a common, chronic immunoinflammatory disease initiated by a complex subgingival...
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Glucosamine Inhibits Lipopolysaccharide-induced Inflammatory Responses in Human Periodontal Ligament Fibroblasts

Kim ED, Park HJ, Baek JH

Glucosamine is commonly taken by the elderly without prescription as a nutritional supplement to attenuate the progression or symptoms of osteoarthritis. Previous studies demonstrated that glucosamine shows anti-inflammatory effects in...
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Micro-computed tomography analysis of changes in the periodontal ligament and alveolar bone proper induced by occlusal hypofunction of rat molars

Shimizu Y, Hosomichi , Nakamura S, Ono T

OBJECTIVE: To three-dimensionally elucidate the effects of occlusal hypofunction on the periodontal ligament and alveolar bone proper of rat molars by micro-computed tomography (micro-CT). METHODS: Occlusal function in the molar area...
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Cytotoxicity of newly developed pozzolan cement and other root-end filling materials on human periodontal ligament cell

Song M, Yoon TS, Kim SY, Kim E

  • KMID: 2316868
  • Restor Dent Endod.
  • 2014 Feb;39(1):39-44.
OBJECTIVES: The purpose of this study was to evaluate in vitro cytotoxicity of the pozzolan cement and other root-end filling materials using human periodontal ligament cell. MATERIALS AND METHODS: Endocem (Maruchi),...
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