Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

PUBLICATION DATE

18 results
Display

Neuregulin 1/ErbB4 signaling attenuates neuronal cell damage under oxygen-glucose deprivation in primary hippocampal neurons

Yoo JY, Kim HB, Yoo SY, Yoo HI, Song DY, Baik TK, Lee JH, Woo RS

The hippocampus is one of the most important brain areas of cognition. This region is particularly sensitive to hypoxia and ischemia. Neuregulin-1 (NRG1) has been shown to be able to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Neuregulin-1 Protects Neuronal Cells Against Damage due to CoCl2-Induced Hypoxia by Suppressing Hypoxia-Inducible Factor-1α and P53 in SH-SY5Y Cells

Yoo SY, Yoo JY, Kim HB, Baik TK, Lee JH, Woo RS

PURPOSE: Hypoxia-mediated neurotoxicity contributes to various neurodegenerative disorders, including Alzheimer disease. Neuregulin-1 (NRG1) plays an important role in the development and plasticity of the brain. The aim of the present...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genome-Wide Association Studies of Autoimmune Thyroid Diseases, Thyroid Function, and Thyroid Cancer

Hwangbo Y, Park YJ

Thyroid diseases, including autoimmune thyroid diseases and thyroid cancer, are known to have high heritability. Family and twin studies have indicated that genetics plays a major role in the development...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Scaffolding Protein, Grb2-associated Binder-1, in Skeletal Muscles and Terminal Schwann Cells Regulates Postnatal Neuromuscular Synapse Maturation

Park SY, Jang SY, Shin YK, Jung DK, Yoon BA, Kim JK, Jo YR, Lee HJ, Park HT

The vertebrate neuromuscular junction (NMJ) is considered as a “tripartite synapse” consisting of a motor axon terminal, a muscle endplate, and terminal Schwann cells that envelope the motor axon terminal....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Impact of Cell Density on Differentiation Efficiency of Rat Adipose-derived Stem Cells into Schwann-like Cells

Najafabadi MM, Bayati V, Orazizadeh M, Hashemitabar M, Absalan F

BACKGROUND AND OBJECTIVES: Schwann-like (SC-like) cells induced from adipose-derived stem cells (ASCs) may be one of the ideal alternative cell sources for obtaining Schwann cells (SCs). They can be used...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Increased Expression of Neuregulin 1 and erbB2 Tyrosine Kinase in the Bladder of Rats With Cyclophosphamide-Induced Interstitial Cystitis

Song KH, Youn CS, Lee CL, Yang SW, Chang YS, Jeong SW, Sul CK

PURPOSE: The aim of this study was to evaluate changes in expressions of neuregulin (NRG)1 and erbB2 tyrosine kinase (ErbB2) in bladders of rats with cyclophosphamide (CYP)-induced interstitial cystitis (IC). METHODS:...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mitogen Activated Protein Kinase Family Proteins and c-jun Signaling in Injury-induced Schwann Cell Plasticity

Lee HJ, Shin YK, Park HT

Schwann cells (SCs) in the peripheral nerves myelinate axons during postnatal development to allow saltatory conduction of nerve impulses. Well-organized structures of myelin sheathes are maintained throughout life unless nerves...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Association between a Missense Polymorphism (rs3924999, Arg253Gln) of Neuregulin 1 and Schizophrenia in Korean Population

Yang SA

Neuregulin 1 (NRG1) is associated with the pathogenesis of schizophrenia through controlling activation and signaling of neurotransmitter receptors. Influence to schizophrenia development by the NRG1 gene may differ in individuals,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on heregulin-beta1-induced MMP-1 and MMP-9 expression in breast cancer cells

Kim S, Han J, Shin I, Kil WH, Lee JE, Nam SJ

  • KMID: 1387358
  • Exp Mol Med.
  • 2012 Aug;44(8):473-482.
Overexpression of HER2 correlates with more aggressive tumors and increased resistance to cancer chemotherapy. However, a functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on tumor metastasis has not...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Prepulse Inhibition of Startle Response: Recent Advances in Human Studies of Psychiatric Disease

Takahashi , Hashimoto , Iwase M, Ishii R, Kamio Y, Takeda M

  • KMID: 2171253
  • Clin Psychopharmacol Neurosci.
  • 2011 Dec;9(3):102-110.
Prepulse inhibition (PPI) is considered to be one of the most promising neurophysiological indexes for translational research in psychiatry. Impairment of PPI has been reported in several psychiatric diseases, particularly...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Expression of ErbB4 in the neurons of Alzheimer's disease brain and APP/PS1 mice, a model of Alzheimer's disease

Woo RS, Lee JH, Yu HN, Song DY, Baik TK

Neuregulin-1 (NRG1) plays important roles in the development and plasticity of the brain, and has also been reported to exhibit potent neuroprotective properties. Although ErbB4, a key NRG1 receptor, is...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Expression of ErbB4 in the apoptotic neurons of Alzheimer's disease brain

Woo RS, Lee JH, Yu HN, Song DY, Baik TK

Neuregulin-1 (NRG1) signaling participates in the synaptic plasticity, maintenance or regulation of adult brain. Although ErbB4, a key NRG1 receptor, is expressed in multiple regions in the adult animal brain,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
An Immunohistochemical Study of ErbB4 Receptor in Alzheimer's Disease Hippocampus

Woo RS, Lee JH, Jung SS, Choy YJ, Yu HN, Oh KM, Song DY, Kwon J, Baik TK

  • KMID: 1472475
  • Korean J Anat.
  • 2009 Dec;42(4):235-244.
Neuregulin-1 (NRG1) signaling participates in numerous neurodevelopmental processes. Although ErbB4, a key NRG1 receptor, is expressed in multiple regions in the adult animal brain, little is known about its expression...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Extracellular Signal-regulated Kinase Activation Is Required for Serine 727 Phosphorylation of STAT3 in Schwann Cells in vitro and in vivo

Lee HK, Jung J, Lee SH, Seo SY, Suh DJ, Park HT

In the peripheral nerves, injury-induced cytokines and growth factors perform critical functions in the activation of both the MEK/ERK and JAK/STAT3 pathways. In this study, we determined that nerve injury-induced...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Expression of Heregulin and ErbB Family Proteins in Gastric Adenocarcinomas: Correlation with Clinopathologic Prognostic Factors

Yoo CH, Lee JH, Choi JS

  • KMID: 2372831
  • J Korean Gastric Cancer Assoc.
  • 2006 Sep;6(3):181-188.
PURPOSE: Heregulin is a natural ligand for erbB3 and erbB4. However, very little is known about their roles in the gastric cancer. This retrospective study was performed to evaluate the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Association of Genetic Variations within 5' end of Neuregulin 1 with Schizophrenia in Korean Population

Park DY, Lee YS, Cho EY, Cho SH, Jang YL, Jeun HO, Jang SY, Yoon SC, Kim JW, Hong KS

  • KMID: 2341075
  • J Korean Neuropsychiatr Assoc.
  • 2005 May;44(3):287-294.
OBJECTIVES: The authors recently found a suggestive evidence of linkage of chromosome 8p21-12 to schizophrenia in Korean multiplex families. Neuregulin 1 (NRG1) was identified in this locus as a positional...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Role of Shc and phosphoinositide 3-kinase in heregulin-induced mitogenic signaling via ErbB3

Kim MS, Koland JG

  • KMID: 1581029
  • Korean J Physiol Pharmacol.
  • 2000 Dec;4(6):507-513.
ErbB3/HER3 is a cell surface receptor which belongs to the ErbB/HER subfamily of receptor protein tyrosine kinases. When expressed in NIH/3T3 cells, ErbB3 can form heterodimeric coreceptor with endogenous ErbB2. Among known intracellular...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Correlation of Heregulin mRNA and Her-2/neu Protein Expression with Node Metastasis and DNA Ploidy Pattern in Human Invasive Breast Carcinoma

Kim YJ, Jung WH, Lee H, Lee SK, Moon IG, Lee KG

  • KMID: 1725419
  • Korean J Pathol.
  • 1998 Aug;32(8):563-573.
The Her-2/neu protooncogene encodes a transmembrane tyrosine kinase that is structurally homologous to the receptor for epidermal growth factor. Its amplification and overexpression are associated with poor prognosis in breast...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr