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Chemical Investigation on an Endophytic fungus Gibberella moniliformis JS1055 Derived from a Halophyte Vitex rotundifolia

Kim JW, Ryu J, Shim SH

Chemical investigation of the ethyl acetate extract of Gibberella moniliformis JS1055 endophytic fungus derived from a halophyte, Vitex rotundifolia, led to the isolation of nine compounds including 7-butyl-6,8-dihydroxy-3(R)-pent-11-enylisochroman-1-one (1), 7-butyl-6,8-dihydroxy-3(R)-pentylisochroman-1-one...
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Characterization of a Biflaviolin Synthase CYP158A3 from Streptomyces avermitilis and Its Role in the Biosynthesis of Secondary Metabolites

Lim YR, Han S, Kim JH, Park HG, Lee GY, Le TK, Yun CH, Kim D

Streptomyces avermitilis produces clinically useful drugs such as avermectins and oligomycins. Its genome contains approximately 33 cytochrome P450 genes and they seem to play important roles in the biosynthesis of...
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An Experimental Study on Comedogenicity of Several External Contactants

Ahn HY, Myung KB, Hahm JH, Kook HI

  • KMID: 2231633
  • Korean J Dermatol.
  • 1985 Oct;23(5):620-629.
The present study was performed to evaluate the comedogenicity of several cosmetic ingredients, vegetable oils, steroid and sulfur. The test materials were applied to one ear canal of rabbits for...
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The Relationship between Serum Cholesterol Levels and Dietary Fatty Acid Patterns, Plasma Fatty Acids, and Other Lipid Profile among Korean Adults

Kim JS, Suh YK, Kim HS, Chang KJ, Choi H

  • KMID: 2301395
  • Korean J Community Nutr.
  • 2003 Apr;8(2):192-201.
The purposes of this research were to assess dietary fatty acid patterns and to elucidate the relationship between the serum cholesterol levels and dietary fatty acid patterns, plasma fatty acid...
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Evaluation of Expression of Lipases and Phospholipases of Malassezia restricta in Patients with Seborrheic Dermatitis

Lee YW, Lee SY, Lee Y, Jung WH

BACKGROUND: Malassezia species (spp.) are cutaneous opportunistic pathogens and associated with various dermatological diseases including seborrheic dermatitis, dandruff and atopic dermatitis. Almost all Malassezia spp. are obligatorily lipid-dependent, which might...
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An Experimental Study on Vehicle Patch Test Tray

Suh MS, Kook HI

Cosmetics contain a number of active agents and ingredients of vehicle. Active agents of cosmetics are known as more common sensitizer. Ingredients of vehicle are weak sensitizer that produce only...
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The effect of IL-1 from keratinocytes on production of IL-2 by peripheral lymphocytes

Eom JY, Kim NI, Sim WY, Haw CR

  • KMID: 2128355
  • Korean J Dermatol.
  • 1992 Dec;30(6):830-840.
The epidermal cell-derived thymocyte activating factor (ETAF) produced by keratinocytes and endowed with IL-1 like activities, can potentiate or stimulate a variety of immune reactionsl. In addition to stimulating thymocyte...
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Inhibitory Effects of CD99-derived Peptide CD99CRIII3 on the Extravasation of Monocytes and Inflammatory Reactions in Contact Dermatitis Mouse Model

Ju HM, Park KH

Leucocyte extravasation has been known to play an important role in inflammatory reactions including contact dermatitis. Previous studies suggested that CD99 regulates β1 integrin activity and may be a novel...
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A Case of Allergic Contact Dermatitis from Silmazine(R) Cream

Kang MC, Kim SA, Chung SL, Lee KS

  • KMID: 2247821
  • Korean J Dermatol.
  • 2009 Jun;47(6):710-713.
Silmazine(R) cream is an antibiotic agent widely used in burn therapy. It consists of Propylene glycol, Stearyl alcohol, Isopropyl Myristate, Sorbitan mono-oleate, Methyl-p-hydroxybenzoate, Polyoxyl 40 stearate and varseline. A 24-year-...
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Molecular Identification of the Vaccine Strain from the Inactivated Rabies Vaccine

Yang DK, Oh YI, Cho SD, Kang HK, Lee KW, Kim YH, Song JY

Since 1994, several different inactivated rabies vaccines have been used to immunize domestic animals such as dogs, cats, and cattle in South Korea. The Korean Veterinary Authority has conducted safety...
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A Case of Chronic Neutrophilic Leukemia Associated with Increased Respiratory Burst Activity of Neutrophils

Lee NR, Im SA, Lee KE, Kim DY, Nam EM, Kim SE, Lee SH, Chang JE, Chang JE, Yeoum MS, Yeoum HJ, Kwon JM, Choi YJ, Seong CM, Lee SN, Seo JY, Huh HJ, Chung WS

  • KMID: 2143340
  • Korean J Hematol.
  • 2001 Nov;36(4):359-363.
Chronic neutrophilic leukemia is a rare myeloproliferative disorder. We have experienced a typical case of chronic neutrophilic leukemia in a 76-year-old man who complained abdominal distension due to hepatosplenomegaly. White...
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Effect of Apocynin on Acute Lung Injury in Rats Given Interleukin-1alpha Intratracheally

Lee YM

  • KMID: 2319532
  • Tuberc Respir Dis.
  • 2011 Jun;70(6):482-489.
BACKGROUND: Based on the assertion that apocynin diminishes acute lung injury (ALI) by inhibition of NADPH oxidase, the effect of apocynin was tested in interleukin-1alpha (IL-1)-induced ALI in rats. METHODS: IL-1...
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Superoxide Anion Generation of Neutrophils in Patients with Atopic Dermatitis

Yeo UC, Kim SH

  • KMID: 1920688
  • Korean J Dermatol.
  • 1990 Dec;28(6):669-676.
Atopic dermatitis is characterized by many signs of immunodeficiency. We have performed this experiment to know whether there are reduced respiratoty burst of neutrophils in patients with atopic dermatitis in...
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The Effect of Phorbol Myristate Actate on the Synthesis of Nitric Oxide in Murine Microglial Cells

Rim GN, Kim JM, Chung HT

  • KMID: 1955055
  • J Korean Neurosurg Soc.
  • 1995 Dec;24(12):1455-1462.
In this study, the effect of phorbol ester on the synthesis of nitric oxide(NO) in murine microglial cells was examined. Phorbol 12-myristate 13-acetate(PMA), a protein kinase C(PKC) activator, alone had...
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Hydrogen Peroxide Production in Neutrophils after Tourniquet Release

Park IH, Lee KB, Song KW, Lee JY, Chun JW

The use of lower extremity tourniquets for procedures of the lower leg is considered routine in orthopedic surgery, but, lower extremity tourniquets do harm occasionally. While the tourniquet is inflated,...
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Quantitative Measurement of Membrane Na+-K+ ATPase Activity using Thallium-201: Comparison with Rubidium-86

Lee JT, Lee IK, Sohn SK, Lee KB

  • KMID: 2078673
  • Korean J Nucl Med.
  • 1998 Apr;32(2):121-128.
PURPOSE: Na+-K+ ATPase Activity has beem estimated by the degree of inhibition of cation transport by cardiac glycosides (ouabain) using Rb-86 as a substrate. The biological characterist-Isc of T1-201 is...
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Protective Effect of PKC Affecting Taxol-induced Cytotoxicity in MCF-7 Cells

Oh JM, Jung KM, Bang HJ, So HS, Park RK, Kim JJ, Choi MK, Park ST, Chung YT

  • KMID: 2224545
  • Korean J Anat.
  • 2000 Oct;33(5):571-578.
Paclitaxel (taxol) is known as effective drug inhibition of cell cycle encouraging activity in human ovarian and metastatic breast cancers and malignant melanoma. It is an antimicrotubule agent that is...
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Protective Effect of PKC and Nitric Oxide Affecting Taxol-Induced Cytotoxicity in C6-Gial Cells

Lee HJ, Kwan SC, Lee HS, Hur JM, Choi DH, Oh JM, Kim JJ, Choi MK, Chung YT

  • KMID: 2092805
  • Korean J Anat.
  • 2003 Oct;36(5):363-370.
Paclitaxel (Taxol) is known as effective drug for inhibition of cell cycle encouraging in human cancer cells. This drug named an antimicrotubule agent which simulate the mitotic arrest towards an...
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Effect of TRH on Phospholipase D Activity in GH3 Cell

Kim DS, Lee CB, Ahn YH, Kim TW, Yoon MS, Han JS

  • KMID: 2199978
  • J Korean Soc Endocrinol.
  • 2002 Aug;17(4):465-472.
BACKGROUND: GH3 cells are a well characterized and widely used model used for the in vitro study of growth hormone (GH) secretion. Thyrotropin releasing hormone (TRH) binds to receptors ...
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Hydrogen Peroxide Production in Neutrophil after Tourniquet Release

Kim YM, Lee SJ, Choi H, Kil HY, Yoon YJ, Chun JW, Lee KB, Park CJ

The use of lower extremity tourniquets for procedures of the lower leg is considered routine in orthopedic surgery, yet, lower extremity tourniquets are not benign. While the tourniquet is inflated,...
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