Nat Prod Sci.  2018 Sep;24(3):189-193. 10.20307/nps.2018.24.3.189.

Chemical Investigation on an Endophytic fungus Gibberella moniliformis JS1055 Derived from a Halophyte Vitex rotundifolia

• Kim JW
• Ryu J
• Shim SH

• KMID: 2422011
• DOI: http://doi.org/10.20307/nps.2018.24.3.189

Abstract

Chemical investigation of the ethyl acetate extract of Gibberella moniliformis JS1055 endophytic fungus derived from a halophyte, Vitex rotundifolia, led to the isolation of nine compounds including 7-butyl-6,8-dihydroxy-3(R)-pent-11-enylisochroman-1-one (1), 7-butyl-6,8-dihydroxy-3(R)-pentylisochroman-1-one (2), 7-butyl-6,8-dihydroxy-3(R)-pentylisochroman-1-one (3), 5α,8α-epidioxyergosta-6,9(11),22-trien-3-ol (4), ergosterol peroxide (5), tetradecanoic acid (6), 8-O-methylfusarubin (7), nicotinic acid (8) and adenosine (9). They were identified by extensive spectroscopic data analysis including 1D, 2D (¹H-¹H COSY, HSQC, HMBC) NMR, and ESIMS. All the isolates (1 - 9) are reported for the first time from this endophytic fungus.

Keyword

Gibberella moniliformis; endophytic fungus; JS1055; Vitex rotundifolia

MeSH Terms

Adenosine
Ergosterol
Fungi*
Gibberella*
Moniliformis*
Myristic Acid
Niacin
Salt-Tolerant Plants*
Statistics as Topic
Vitex*
Adenosine
Ergosterol
Myristic Acid
Niacin

Figure

• 

  Fig. 1 The structures of 1 - 9 isolated from G. moniliformis (JS1055) fungi derived from V. rotundifolia.

• 

  Fig. 2 Key 1H-1H COSY (bold) and HMBC ( →) correlations of compounds 1 and 7.

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