- Muscarinic receptor subtype controlling the carbachol-induced muscle contraction in guinea pig gastric antrum
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Rhee JC, Uhm DY, Kang TM
- KMID: 1982596
- Korean J Physiol Pharmacol.
- 2000 Apr;4(2):105-111.
Stimulation of muscarinic receptors by carbachol (CCh) in the circular smooth muscle of the guinea pig gastric antrum causes muscle contraction. In the present study, muscarinic receptor subtype controlling the muscle contraction in... -
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- Issues on Safety of Long-Acting Muscarinic Antagonist
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Lee YD, Cho Y, Han MS
- KMID: 2319504
- Tuberc Respir Dis.
- 2011 May;70(5):384-389.
The prevention of and the controlling of symptoms, reductions in the frequency of exacerbations, and disease severity are central to the pharmacologic therapy of chronic obstructive pulmonary disease (COPD). COPD... -
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- Review of the Anticholinergics for the Treatment of Overactive Bladder: 2009 Update
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Oh SJ
- KMID: 2331537
- J Korean Continence Soc.
- 2009 Jun;13(1):7-22.
Overactive bladder is a chronic condition defined by bothersome urgency with or without urgency incontinence, usually associated with daytime frequency and nocturia. The treatment of this condition is to control... -
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- Positioning of Long-Acting Muscarinic Antagonists in the Management of Asthma
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Aalbers R, Park HS
- KMID: 2383985
- Allergy Asthma Immunol Res.
- 2017 Sep;9(5):386-393.
- doi: 10.4168/aair.2017.9.5.386
Despite a range of efficacious therapies for asthma, including inhaled corticosteroids (ICS) and long-acting β₂-agonists (LABA), a significant proportion of patients have poor asthma control and retain a risk of... -
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- Future directions in overactive bladder treatment: Personalized medicine can be applied?
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Lee KS
- KMID: 2344108
- Korean J Urol.
- 2015 Oct;56(10):671-672.
- doi: 10.4111/kju.2015.56.10.671
No abstract available. -
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- Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding
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Yamada S, Kuraoka S, Osano A, Ito Y
- KMID: 2232961
- Int Neurourol J.
- 2012 Sep;16(3):107-115.
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed. Transdermal administration of oxybutynin... -
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- Drug treatment for lower urinary tract symptoms
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Han JY, Choo MS
- KMID: 2190753
- J Korean Med Assoc.
- 2011 Jun;54(6):637-645.
- doi: 10.5124/jkma.2011.54.6.637
Lower urinary tract symptoms (LUTS) are classified into three groups: storage, voiding, and post-micturition symptoms. The most popular causes of LUTS are benign prostatic hyperplasia (BPH) and overactive bladder (OAB).... -
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- Local Effects of Antimuscarinics on Muscarinic Receptors in Bladder Sensory Nerves
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Park MS, Cho SW, Han KH, Lee SC, Kim WJ, Kim YT
- KMID: 2330522
- J Korean Continence Soc.
- 2006 Jun;10(1):17-22.
PURPOSE: To investigate the role of muscarinic receptors in bladder sensory mechanism. MATERIALS AND METHODS: Normal adult volunteers collected voided urine after taking five days of trospium(20 mg bid), tolterodine LA(4... -
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- The Effects of Atropine and Glycopyrrolate on the Recovery from Mivacurium: Induced Neuromuscular Blockade in the Rabbit
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Kwon OK, Kim CS
- KMID: 1860463
- Korean J Anesthesiol.
- 1996 Apr;30(4):419-425.
- doi: 10.4097/kjae.1996.30.4.419
BACKGROUND: Antimuscarinic agents are used to block undesirable muscarinic effects of `anticholinesterase given to reverse the residual neuromuscular blockade produced by muscle relaxants. However, besides antimuscarinic effects, atropine was known... -
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- Overactive Bladder
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Lee KS, Lee YS
- KMID: 1990140
- Korean J Urol.
- 2007 Dec;48(12):1191-1208.
- doi: 10.4111/kju.2007.48.12.1191
Overactive bladder(OAB) is a symptom syndrome including urinary urgency with or without urinary incontinence, usually with frequency and nocturia. Urgency, defined as the compelling feeling of impending incontinence that is... -
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- Oral pharmacological therapy for urinary incontinence
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Kim DK
- KMID: 2382726
- J Korean Med Assoc.
- 2016 Mar;59(3):215-220.
- doi: 10.5124/jkma.2016.59.3.215
Urinary incontinence (UI) has been a serious health problem which can significantly affect quality of life. UI may occur at any age but more common in the elderly population. Many... -
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- Effects of Intravesical Instillation of Antimuscarinics on Bladder Overactivity Induced by Intravesical Instillation of Adenosine Triphosphate in Rats
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Lee SB, Lee JW, Kim YT
- KMID: 2311867
- Korean J Urol.
- 2009 Apr;50(4):396-400.
PURPOSE: Adenosine triphosphate (ATP) from the urothelium acts as a sensory neurotransmitter and is augmented in many diseases, such as overactive bladder. We investigated the effects of intravesical instillation of... -
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- Persistence and compliance with medication management in the treatment of overactive bladder
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Kim TH, Lee KS
- KMID: 2363129
- Investig Clin Urol.
- 2016 Mar;57(2):84-93.
- doi: 10.4111/icu.2016.57.2.84
Overactive bladder (OAB) is a common and chronic condition that impacts patients' daily activities and quality of life. Pharmaco-therapy for OAB is a mainstay of treatment. Antimuscarinics and beta3-adrenoceptor agonists... -
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- Optimal Bronchodilation for COPD Patients: Are All Long-Acting β₂-Agonist/Long-Acting Muscarinic Antagonists the Same?
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Miravitlles M, Baek S, Vithlani V, Lad R
- KMID: 2414562
- Tuberc Respir Dis.
- 2018 Jul;81(3):198-215.
- doi: 10.4046/trd.2018.0040
Bronchodilators provide improvements in lung function and reductions in symptoms and exacerbations, and are the mainstay of pharmacological management of chronic obstructive pulmonary disease (COPD). The Global Initiative for Chronic... -
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- Efficacy and Tolerability of Tolterodine Compared to Oxybutynin in Children with a Neurogenic Bladder
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Kim KM, Lee SW
- KMID: 2294073
- Korean J Urol.
- 2005 Jun;46(6):598-603.
PURPOSE: The aim of this study was to investigate the efficacy and adverse effects of oral tolterodine compared to oxybutynin in children with a neurogenic bladder. MATERIALS AND METHODS: 16 patients,... -
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- Influence of solifenacin on the improvement of storage symptoms in the early period after photoselective vaporization of the prostate
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Kim SJ, Bae WJ, Kim SW
- KMID: 2461060
- Investig Clin Urol.
- 2019 Nov;60(6):480-487.
- doi: 10.4111/icu.2019.60.6.480
PURPOSE: We studied the effect of solifenacin on reducing storage symptoms after photoselective vaporization of the prostate (PVP). MATERIALS AND METHODS: This study included patients with persistent storage symptoms of urgency... -
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- Bladder Wall Thickness is Associated with Responsiveness of Storage Symptoms to Alpha-Blockers in Men with Lower Urinary Tract Symptoms
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Park JS, Lee HW, Lee SW, Moon HS, Park HY, Kim YT
- KMID: 1988761
- Korean J Urol.
- 2012 Jul;53(7):487-491.
- doi: 10.4111/kju.2012.53.7.487
PURPOSE: Bladder wall thickness (BWT) is reported to be related to detrusor overactivity and bladder outlet obstruction. We investigated the relationship between BWT and the responsiveness of storage symptoms to... -
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- Clinical Factors Associated With Dose Escalation of Solifenacin for the Treatment of Overactive Bladder in Real Life Practice
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Chun JY, Song M, Han JY, Na S, Hong B, Choo MS
- KMID: 2232917
- Int Neurourol J.
- 2014 Mar;18(1):23-30.
PURPOSE: To determine the baseline clinical characteristics associated with dose escalation of solifenacin in patients with overactive bladder (OAB). METHODS: We analyzed the data of patients with OAB (micturition frequency >... -
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- Spinal Gabapentin and Antinociception: Mechanisms of Action
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Yoon MH, Choi JI, Jeong SW
- KMID: 2157631
- J Korean Med Sci.
- 2003 Apr;18(2):255-261.
- doi: 10.3346/jkms.2003.18.2.255
Spinal gabapentin has been known to show the antinociceptive effect. Although several assumptions have been suggested, mechanisms of action of gabapentin have not been clearly established. The present study was... -
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- Long-Term Efficacy of Mirabegron Add-On Therapy to Antimuscarinic Agents in Patients With Spinal Cord Injury
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Han SH, Cho IK, Jung JH, Jang SH, Lee BS
- KMID: 2440952
- Ann Rehabil Med.
- 2019 Feb;43(1):54-61.
- doi: 10.5535/arm.2019.43.1.54
OBJECTIVE: To evaluate the long-term efficacy of mirabegron add-on therapy in patients with spinal cord injury (SCI) based on an urodynamic study. METHODS: This retrospective study involved a chart audit of... -
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