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Long-Term Efficacy of Mirabegron Add-On Therapy to Antimuscarinic Agents in Patients With Spinal Cord Injury

Han SH, Cho IK, Jung JH, Jang SH, Lee BS

OBJECTIVE: To evaluate the long-term efficacy of mirabegron add-on therapy in patients with spinal cord injury (SCI) based on an urodynamic study. METHODS: This retrospective study involved a chart audit of...
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Influence of solifenacin on the improvement of storage symptoms in the early period after photoselective vaporization of the prostate

Kim SJ, Bae WJ, Kim SW

PURPOSE: We studied the effect of solifenacin on reducing storage symptoms after photoselective vaporization of the prostate (PVP). MATERIALS AND METHODS: This study included patients with persistent storage symptoms of urgency...
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Optimal Bronchodilation for COPD Patients: Are All Long-Acting β₂-Agonist/Long-Acting Muscarinic Antagonists the Same?

Miravitlles M, Baek S, Vithlani V, Lad R

Bronchodilators provide improvements in lung function and reductions in symptoms and exacerbations, and are the mainstay of pharmacological management of chronic obstructive pulmonary disease (COPD). The Global Initiative for Chronic...
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Influence of the Short-term Intake of High Doses of Solifenacin and Trospium on Cognitive Function and Health-Related Quality of Life in Older Women With Urinary Incontinence

Kosilov K, Kuzina I, Loparev S, Gainullina Y, Kosilova L, Prokofyeva A

PURPOSE: The aim of this study was to investigate the safety and the effects of elevated doses of solifenacin and trospium on cognitive function and health-related quality of life (HRQoL)...
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Evaluation of the incidence and risk factors associated with persistent frequency in interstitial cystitis/bladder pain syndrome and the efficacy of antimuscarinic treatment

Kim A, Hoe KO, Shin JH, Choo MS

PURPOSE: To investigate the incidence and risk factors associated with persistent urinary frequency, and to evaluate the efficacy of antimuscarinic treatment. MATERIALS AND METHODS: Interstitial cystitis/bladder pain syndrome (IC/BPS) patients complaining...
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Positioning of Long-Acting Muscarinic Antagonists in the Management of Asthma

Aalbers R, Park HS

Despite a range of efficacious therapies for asthma, including inhaled corticosteroids (ICS) and long-acting β₂-agonists (LABA), a significant proportion of patients have poor asthma control and retain a risk of...
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Additional low-dose antimuscarinics can improve overactive bladder symptoms in patients with suboptimal response to beta 3 agonist monotherapy

Shin JH, Kim A, Choo MS

PURPOSE: We aimed to assess the patient-reported outcome (PRO) and efficacy of add-on low-dose antimuscarinic therapy in over-active bladder (OAB) patients with suboptimal response to 4-week treatment with beta 3...
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Long-term adherence to antimuscarinic drugs when treating overactive bladder in the older: Subjective reason and objective factors

Kosilov KV, Loparev SA, Kuzina IG, Geltser BI, Shakirova , Zhuravskaya NS, Lobodenko

PURPOSE: Comparison of subjective reasons for the refusal of antimuscarinic treatment and the state of objective economic, social, psychological and health status markers in the elderly with overactive bladder. MATERIALS AND...
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Incidence and risk factors of recurrence of overactive bladder symptoms after discontinuation of successful medical treatment

Kim A, Lee KS, Kim TB, Kim HJ, Yoo ES, Yun JH, Kim DY, Jung SG, Lee JT, Kim JM, Oh CK, Shin JH, Jeon SH, Lee SH, Han CH, Lee DH, Cho HJ, Choo MS

PURPOSE: To identify incidence and risk factors of recurrence after discontinuation of successful antimuscarinic therapy in patients with overactive bladder (OAB). MATERIALS AND METHODS: This was a prospective, multicenter trial. Patients...
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Social, Economic, and Medical Factors Associated With Solifenacin Therapy Compliance Among Workers Who Suffer From Lower Urinary Tract Symptoms

Kosilov KV, Alexandrovich LS, Gennadyevna KI, Viktorovna SO, Sergeevna , Ivanovich

PURPOSE: The prevalence of hyperactive-type lower urinary tract symptoms is 45.2%, with shares of overactive bladder (OAB) and urge incontinence (UI) symptoms of 10.7% and 8.2%, respectively. We investigated the...
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Oral pharmacological therapy for urinary incontinence

Kim DK

Urinary incontinence (UI) has been a serious health problem which can significantly affect quality of life. UI may occur at any age but more common in the elderly population. Many...
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Persistence and compliance with medication management in the treatment of overactive bladder

Kim TH, Lee KS

Overactive bladder (OAB) is a common and chronic condition that impacts patients' daily activities and quality of life. Pharmaco-therapy for OAB is a mainstay of treatment. Antimuscarinics and beta3-adrenoceptor agonists...
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Long-term Combination Therapy With α-Blockers and 5α-Reductase Inhibitors in Benign Prostatic Hyperplasia: Patient Adherence and Causes of Withdrawal From Medication

Ong HL, Liao CH, Kuo HC

PURPOSE: To investigate long-term therapeutic effects and patient adherence to a combination therapy of a 5α-reductase inhibitor and an α-blocker and to identify causes of withdrawal from medication in patients...
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New pharmacotherapy for treating overactive bladder: mirabegron and botulinum toxin

Kim TH, Lee KS

Overactive bladder (OAB) is a symptom-driven condition characterized by urinary urgency with or without urinary incontinence and a common problem that can significantly affect quality of life. Drugs that prevent...
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The Role of Bronchodilators in Preventing Exacerbations of Chronic Obstructive Pulmonary Disease

Beeh KM

Bronchodilators are the cornerstone of symptomatic chronic obstructive pulmonary disease (COPD) treatment. They are routinely recommended for symptom reduction, with a preference of long-acting over short-acting drugs. Bronchodilators are classified...
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Practical Aspects of Botulinum Toxin-A Treatment in Patients With Overactive Bladder Syndrome

Liao CH, Kuo HC

Intravesical onabotulinumtoxinA (BoNT-A) injection is an effective treatment for overactive bladder syndrome (OAB) that is refractory to antimuscarinics. An injectable dose of 100 U has been suggested to achieve the...
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Characteristics of urinary retention in female inpatients managed with medical treatments

Lee CY, Kim CS, Cho WJ

PURPOSE: We aimed to analyze the characteristics of urinary retention (UR) in female inpatients managed with medical treatments. MATERIALS AND METHODS: We retrospectively analyzed the medical records of female inpatients referred...
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Factors affecting medication discontinuation in patients with overactive bladder symptoms

Shim EJ, Yoo EH, Kim YM, Kim D

OBJECTIVE: To find out the factors affecting medication discontinuation in patients with overactive bladder (OAB) symptoms. METHODS: The clinical data of 125 patients with OAB symptoms who had taken antimuscarinics and...
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Drug therapy of overactive bladder - What is coming next?

Andersson

After the approval and introduction of mirabegron, tadalafil, and botulinum toxin A for treatment of lower urinary tract symptoms/overactive bladder, focus of interest has been on their place in therapy...
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Future directions in overactive bladder treatment: Personalized medicine can be applied?

Lee KS

No abstract available.
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