- Mitochondrial Homeostasis Molecules: Regulation by a Trio of Recessive Parkinson's Disease Genes
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Han JY, Kim JS, Son JH
- KMID: 2165539
- Exp Neurobiol.
- 2014 Dec;23(4):345-351.
- doi: 10.5607/en.2014.23.4.345
Mitochondria are small organelles that produce the majority of cellular energy as ATP. Mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson's disease (PD), and rare familial forms of... -
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- Cellular NAD⺠Level: A Key Determinant of Mitochondrial Quality and Health
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Hwang ES, Hwang SY
- KMID: 2401128
- Ann Geriatr Med Res.
- 2017 Dec;21(4):149-157.
- doi: 10.4235/agmr.2017.21.4.149
The quality of mitochondria is a key determinant of mitochondrial ATP production and reactive oxygen species generation; therefore, it plays critical roles in energy homeostasis and cellular health. Mitochondrial quality... -
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- The Relationship between Mitochondria and NLRP3 Inflammasome
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Lee HA, Na HS, Chung J
- KMID: 2394576
- Int J Oral Biol.
- 2017 Sep;42(3):85-90.
- doi: 10.11620/IJOB.2017.42.3.085
Mitochondria participate in various intracellular metabolic pathways such as generating intracellular ATP, synthesizing several essential molecules, regulating calcium homeostasis, and producing the cell's reactive oxygen species (ROS). Emerging studies have... -
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- Mitochondrial Quality Control in the Heart: New Drug Targets for Cardiovascular Disease
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Oh CM, Ryu D, Cho S, Jang Y
- KMID: 2471778
- Korean Circ J.
- 2020 May;50(5):395-405.
- doi: 10.4070/kcj.2019.0416
Despite considerable efforts to prevent and treat cardiovascular disease (CVD), it has become the leading cause of death worldwide. Cardiac mitochondria are crucial cell organelles responsible for creating energy-rich ATP... -
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- Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle
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Heo JW, No MH, Park DH, Kang JH, Seo DY, Han J, Neufer PD, Kwak HB
- KMID: 2395251
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):567-577.
- doi: 10.4196/kjpp.2017.21.6.567
Obesity is known to induce inhibition of glucose uptake, reduction of lipid metabolism, and progressive loss of skeletal muscle function, which are all associated with mitochondrial dysfunction in skeletal muscle.... -
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- Effects of Acute Exercise on Mitochondrial Function, Dynamics, and Mitophagy in Rat Cardiac and Skeletal Muscles
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Yoo SZ, No MH, Heo JW, Park DH, Kang JH, Kim JH, Seo DY, Han J, Jung SJ, Kwak HB
- KMID: 2448804
- Int Neurourol J.
- 2019 Feb;23(Suppl 1):S22-S31.
- doi: 10.5213/inj.1938038.019
PURPOSE: This study aimed to investigate the effects of single-bout exercise on mitochondrial function, dynamics (fusion, fission), and mitophagy in cardiac and skeletal muscles. METHODS: Fischer 344 rats (4 months old)... -
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- Etoposide Induces Mitochondrial Dysfunction and Cellular Senescence in Primary Cultured Rat Astrocytes
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Bang M, Kim DG, Gonzales E, Kwon KJ, Shin CY
- KMID: 2462880
- Biomol Ther.
- 2019 Nov;27(6):530-539.
- doi: 10.4062/biomolther.2019.151
Brain aging is an inevitable process characterized by structural and functional changes and is a major risk factor for neurodegenerative diseases. Most brain aging studies are focused on neurons and... -
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- Improvement Characteristics of Bio-active Materials Coated Fabric on Rat Muscular Mitochondria
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Lee D, Kim YW, Kim JH, Yang M, Bae H, Lim I, Bang H, Go KC, Yang GW, Rho YH, Park HS, Park EH, Ko JH
- KMID: 1791431
- Korean J Physiol Pharmacol.
- 2015 May;19(3):283-289.
- doi: 10.4196/kjpp.2015.19.3.283
This study surveys the improvement characteristics in old-aged muscular mitochondria by bio-active materials coated fabric (BMCF). To observe the effects, the fabric (10 and 30%) was worn to old-aged rat... -
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- The Phosphodiesterase 4 Inhibitor Roflumilast Protects against Cigarette Smoke Extract-Induced Mitophagy-Dependent Cell Death in Epithelial Cells
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Kyung SY, Kim YJ, Son ES, Jeong SH, Park JW
- KMID: 2420602
- Tuberc Respir Dis.
- 2018 Apr;81(2):138-147.
- doi: 10.4046/trd.2017.0115
BACKGROUND: Recent studies show that mitophagy, the autophagy-dependent turnover of mitochondria, mediates pulmonary epithelial cell death in response to cigarette smoke extract (CSE) exposure and contributes to the development of... -
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- The Role of Autophagy Associated With Causative Genes for Parkinson's Disease
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Ho DH, Seo H, Son I, Seol W
- KMID: 2343520
- J Korean Neurol Assoc.
- 2014 Aug;32(3):137-144.
Parkinson's disease (PD) is the second most common neurodegenerative motor disorder, affecting approximately 1% of the population aged > or =60 years. Recent investigations have shown that in addition to... -
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- Current Understanding of HMGB1-mediated Autophagy
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Kwak MS, Shin JS
- KMID: 2168685
- J Bacteriol Virol.
- 2013 Jun;43(2):148-154.
- doi: 10.4167/jbv.2013.43.2.148
Reactive oxygen species (ROS) is an oxidative stress to which cells respond by activating various defense mechanisms or cell death. Autophagy associated with oxidative stress response is a process to... -
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