- Increased Serum Activity of Matrix Metalloproteinase-9 in Patients with Acute Variceal Bleeding
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Kwon OS, Jung HS, Bae KS, Jung YK, Kim YS, Choi DJ, Kim YS, Kim JH
- KMID: 2284272
- Gut Liver.
- 2012 Apr;6(2):249-255.
BACKGROUND/AIMS: Matrix metalloproteinases (MMP)-2 and -9 can degrade essential components of vascular integrity. The aim of this study was to investigate the association between those MMPs and variceal bleeding (VB). METHODS:... -
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- Regulation of Matrix Metalloproteinase 2 Expression by an Adenosine A1 Agonist in Trabecular Meshwork Cells
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Baek MJ, Kim KH, Kim JW
- KMID: 2422583
- J Korean Ophthalmol Soc.
- 2018 Oct;59(10):946-952.
- doi: 10.3341/jkos.2018.59.10.946
PURPOSE: We investigated the extent of adenosine A1 agonist-induced expression and regulation of matrix metalloproteinase 2 (MMP-2) synthesis in human trabecular meshwork cells (HTMC). METHODS: Primary HTMC cultures were exposed to... -
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- Expression of MMP-2, MT1-MMP, and TIMP-2 mRNA in Breast Carcinomas
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Kim DW, Jin SY, Lee DW
- KMID: 1979368
- Korean J Pathol.
- 2003 Dec;37(6):400-406.
BACKGROUND: The activation of proMMP-2 is induced by membrane type 1-matrix metalloproteinase (MT1-MMP), but inhibited by tissue inhibitors of matrix metalloproteinase type 2 (TIMP-2). This study was carried out to... -
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- Expression of matrix metalloproteinase-2 and survivin in endometrioid and nonendometrioid endometrial cancers and clinicopathologic significance
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Yilmaz E, Koyuncuoglu M, Gorken IB, Okyay E, Saatli B, Ulukus EC, Saygili U
- KMID: 2288572
- J Gynecol Oncol.
- 2011 Jun;22(2):89-96.
- doi: 10.3802/jgo.2011.22.2.89
OBJECTIVE: To determine matrix metalloproteinase-2 and survivin expressions in endometrial cancers, their relation to clinical and histologic parameters and to investigate any difference in the expression of these markers between... -
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- Altered Expression of Tissue Inhibitor of Matrix Metalloproteinase-2 in Complicated Mice Heart Secondary to Experimentally Induced Viral Myocarditis
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Kim SS, Eom DW, Woo YJ, Suh JH, Huh J, Hong YM, Choi I
- KMID: 2275603
- Korean J Pathol.
- 2001 Jun;35(3):196-200.
BACKGROUND: The pathogenesis of transition from viral myocarditis to dilated cardiomyopathy is elusive, although the incidence of dilated cardiomyopathy in human is increasing. METHODS: To clarify the role of the... -
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- Expression of Placental Gelatinases in Normal and Preeclamptic Pregnancy
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Roh JR, Oh WJ, CHoi JJ, Moon JS, Hwang JD, Yang SH
- KMID: 2261394
- Korean J Obstet Gynecol.
- 1999 Jun;42(6):1196-1200.
OBJECTIVES: The aim of this study was to compare activities of gelatinases and their regulators in normal and preeclamptic placenta tissue. METHODS: The activities of gelatinase A and B were... -
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- Expression of Matrix Metalloproteinase-2 and -13 and Tissue Inhibitor of Metalloproteinase-4 in Varicose Veins
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Chang JW, Maeng YH, Kim SW
- KMID: 1447769
- Korean J Thorac Cardiovasc Surg.
- 2011 Dec;44(6):387-391.
- doi: 10.5090/kjtcs.2011.44.6.387
BACKGROUND: The relationship between the degree of expression of matrix metalloproteinases or tissue inhibitor of metalloproteinases and venous reflux remains to be investigated. MATERIALS AND METHODS: Primary varicose vein tissues were... -
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- Significance of Increased Expression of the Tissue Inhibitor of Matrix Metalloproteinase-2 in Human Colorectal Carcinomas
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Kim KH, Shim KS, Kim SS, Park EB
- KMID: 2206449
- J Korean Surg Soc.
- 1998 Dec;55(Suppl):1022-1028.
BACKGROUND : Tumor invasion and metastasis are the major causes of morbidity and death for cancer patients. Metastasis is a complex multistep process in which tumor cells must pass through... -
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- Expression of Matrix Metalloproteinase-2 (MMP-2) and Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) in Pancreatic Ductal Adenocarcinoma
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Gu MJ, Bae YK, Choi JH
- KMID: 2275507
- Korean J Pathol.
- 2004 Apr;38(2):73-78.
BACKGROUND: Matrix metalloproteinase-2 (MMP-2) is known to be one of the key molecules for tumor invasion and metastasis. MMP-2 activity is modulated through interaction with the tissue inhibitor of metalloproteinase-2... -
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- Effects of Hepatocyte Growth Factor on Collagen Synthesis and Matrix Metalloproteinase Production in Keloids
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Lee WJ, Park SE, Rah DK
- KMID: 1777848
- J Korean Med Sci.
- 2011 Aug;26(8):1081-1086.
- doi: 10.3346/jkms.2011.26.8.1081
Keloids are pathologic proliferations of the dermal layer of the skin resulting from excessive collagen production and deposition. Hepatocyte growth factor (HGF) increases the expression of matrix metalloproteinase (MMP)-1 and... -
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- Immunolocalization of Matrix Metalloproteinase-2, -9 and Tissue Inhibitor of Metalloproteinase-1, -2 in Suture-induced Corneal Neovascularization
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Heo JG, Kim WS, Hwang DG
- KMID: 2337021
- J Korean Ophthalmol Soc.
- 2002 Jun;43(6):1051-1061.
PURPOSE: Metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) have been linked to the angiogenic process in general. In order to understand the potential roles of MMPs and TIMPs in... -
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- The Clinical Significance of the Expression of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Renal Cell Carcinoma
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Kim JY, Park TC, Baek SH
- KMID: 1997140
- Korean J Urol.
- 2006 Apr;47(4):347-352.
- doi: 10.4111/kju.2006.47.4.347
PURPOSE: Matrix metalloproteinases (MMPs) are endogenous peptidases that are capable of degrading various components of the basement membranes. To evaluate the clinical significance of the expressions of MMPs in renal... -
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- The Plasma Level of Matrix Metalloproteinase (MMP)-2, -9 between Antepartum and Postpartum Period in Preeclampsia
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Chang HJ, Yang JI, Kim HB, Kim HS, Ryu HS, Oh KS
- KMID: 2077113
- Korean J Obstet Gynecol.
- 2004 Aug;47(8):1487-1491.
OBJECTIVE: To evaluate the changes of plasma MMP-2, -9 levels in preeclampsia between antepartum and postpartum periods, and compare with normotensive pregnant. METHODS: Plasma MMP-2, -9 levels were determined with enzyme-linked... -
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- The Matrix metalloproteinase-2 & -9, Tissue inhibitor of metalloproteinase-1 & -2 mRNA Expression in Invasive Cervical Cancer
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Moon HS, Choi EA, Yoo MY, Chung HW
- KMID: 2076200
- Korean J Obstet Gynecol.
- 2001 Mar;44(3):532-539.
OBJECTIVE: Invasive cancer cells penetrate the extracellular matrix(ECM), including basement membrane during the metastatic cascades. Matrix metalloproteinases(MMPs) play a critical role in tumor invasion and metastasis and their activities are... -
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- Influence of Transforming Growth Factor-alpha on Expression of Matrix metalloproteinase-2 and Matrix metalloproteinase-9 mRNA in Mouse Embryos
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Kim CH, Kim SH, Park EJ, Hong SH, Chae HD, Kang BM
- KMID: 2262666
- Korean J Obstet Gynecol.
- 2002 Mar;45(3):443-449.
OBJECTIVE: To investigate the influence of transforming growth factor-alpha (TGF-alpha) on the expression of Matrix metalloproteinase-2 (MMP-2) and Matrix metalloproteinase-9 (MMP-9) mRNA in mouse embryos. MATERIALS AND METHOD: Eight-cell stage mouse... -
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- Effect of Oxidative Stress on the Expression of Gelatinases in Cultured RPE
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Park YC, Choi GJ
- KMID: 2337230
- J Korean Ophthalmol Soc.
- 2005 Nov;46(11):1903-1910.
PURPOSE: To evaluate the expression pattern of gelatinases in the human retinal pigment epithelial cell line ARPE-19 in response to oxidative stress. METHODS: ARPE-19 cells were exposed to paraquat for... -
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- The Relationship Between the Activity of Matrix Metalloproteinase in the Aqueous Humor and the Development of Primary Open Angle Glaucoma
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Kee CW, Son SS, Ahn BH
- KMID: 2124089
- J Korean Ophthalmol Soc.
- 1998 Mar;39(3):544-550.
To investigate whether the abnormal expression of matrix metalloproteinases(MMPs) in the aqueous humor may case the development of glaucoma, the activity of MMP in the aqueous humor of galucoma and... -
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- Matrix Metalloproteinase-2, -9 Immunohistochemical staining in Cervical carcinoma: The Relationship with Clinicopathologic Prognostic Factors
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Chung JY, Kim YM, Kim YT, Nam JH, Gong GY
- KMID: 2076348
- Korean J Obstet Gynecol.
- 2001 Sep;44(9):1671-1677.
OBJECTIVE: Matrix metalloproteinase (MMP) has been reported to have a key role in the sequence of events that lead to local tumor invasion and metastasis. The present study was conducted... -
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- Influence of Transforming Growth Factor-alpha on Expression of Matrix Metalloproteinase-2, 9 and Epidermal Growth Factor Receptor Gene in the Mouse Blastocysts
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Kim JH, Hong SH, Nah HY, Lee JY, Chae HD, Kim CH, Kang BM, Bae IH
- KMID: 1979127
- Korean J Fertil Steril.
- 2001 Sep;28(3):173-182.
No abstract available. -
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- Role of Matrix Metalloproteinase (MMP) 2 and MMP-9 in Soft Tissue Sarcoma
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Yang HK, Jeong KC, Kim YK, Jung ST
- KMID: 1794734
- Clin Orthop Surg.
- 2014 Dec;6(4):443-454.
- doi: 10.4055/cios.2014.6.4.443
BACKGROUND: We investigated the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in malignant fibrous histiocytoma (MFH), and determined whether these could be useful as prognostic factors. METHODS:... -
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