- A Case of Lactic Acidosis Associated with Prolonged Linezolid Therapy
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Chung SK, Jeon JS, Kim TH, Kim C, Kwon SH, Noh HJ, Han DC
- KMID: 2253204
- Korean J Nephrol.
- 2009 Jan;28(1):41-43.
Lactic acidosis is the most common cause of metabolic acidosis in hospitalized patients. Although impaired tissue oxygenation is usually responsible for the rise in lactate production, lactic acidosis could be... -
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- A Case of Linezolid-Associated Lactic Acidosis
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Lee HJ, Choi JH, Kim SY, Chung KH, Lee TW, Ihm CG, Moon JY
- KMID: 2264256
- Korean J Med.
- 2012 Mar;82(3):371-373.
Linezolid has been used for treatment of vancomycin-resistant Enterococcus faecium infection, nosocomial pneumonia caused by Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus or Streptococcus pneumoniae, and complicated and uncomplicated skin and... -
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- Vancomycin-Resistant Enterococcus Meningitis
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Ryu WS, Bae EK, Kim JS, Erm GH, Jung KH, Park HK, Chu K
- KMID: 2185077
- J Korean Neurol Assoc.
- 2008 Aug;26(3):273-276.
The incidence of vancomycin-resistant enterococcus (VRE) meningitis is increasing. We present a 56-year-old man who suffered from VRE meningitis after cerebellar hemorrhage and intraventricular catheter insertion. The patient recovered completely... -
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- Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus in Korea: High Rate of False Resistance to Linezolid by the VITEK 2 System
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Yoo IY, Kang OK, Shim HJ, Huh HJ, Lee NY
- KMID: 2457494
- Ann Lab Med.
- 2020 Jan;40(1):57-62.
- doi: 10.3343/alm.2020.40.1.57
As various linezolid resistance mechanisms have been identified in methicillin-resistant Staphylococcus aureus (MRSA), we investigated the molecular characteristics of MRSA with elevated linezolid minimum inhibitory concentrations (MICs), using the VITEK... -
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- Vancomycin-Resistant Enterococcus faecium Meningitis Treated with Linezolid: A Case Report and Review of the Literature
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Lee CS, Park SJ, Lee YC, Rhee YK, Lee HB
- KMID: 2170310
- Infect Chemother.
- 2010 Jun;42(3):194-197.
- doi: 10.3947/ic.2010.42.3.194
Vancomycin-resistant enterococci (VRE) infection is a serious problem because optimal therapy has not been established. Different agents in various combinations, including teicoplanin, chloramphenicol, and quinupristin/dalfopristin, have been used to treat... -
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- A Case of Lactic Acidosis Caused by Linezolid Treatment of Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia
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Kim YS, Kim JB, Lee Y, Kim SH, Choi SH, Woo JH, Kim YS
- KMID: 2264306
- Korean J Med.
- 2012 Apr;82(4):512-515.
Linezolid is an antibiotic in the oxazolidinone family that works as a bacterial protein synthesis inhibitor. It is used for the treatment of Gram-positive, multidrug-resistant bacteria. Adverse effects of linezolid... -
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- Optic Neuropathy after Taking Linezolid
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Yoon YS, Lee CK
- KMID: 2466197
- J Korean Ophthalmol Soc.
- 2019 Dec;60(12):1363-1368.
- doi: 10.3341/jkos.2019.60.12.1363
PURPOSE: We report a case of optic neuropathy in a patient who was treated with pre-extensively drug-resistant tuberculosis(pre-XDR TB) treatment with linezolid. CASE SUMMARY: A 61-year-old male patient with no other... -
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- Delamanid, Bedaquiline, and Linezolid Minimum Inhibitory Concentration Distributions and Resistance-related Gene Mutations in Multidrug-resistant and Extensively Drug-resistant Tuberculosis in Korea
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Yang JS, Kim KJ, Choi H, Lee SH
- KMID: 2429122
- Ann Lab Med.
- 2018 Nov;38(6):563-568.
- doi: 10.3343/alm.2018.38.6.563
BACKGROUND: Delamanid, bedaquiline, and linezolid have recently been approved for the treatment of multidrug- and extensively drug-resistant (MDR and XDR, respectively) tuberculosis (TB). To use these drugs effectively, drug susceptibility... -
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- Emergence of optrA-Mediated Linezolid-Nonsusceptible Enterococcus faecalis in a Tertiary Care Hospital
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Park K, Jeong YS, Chang J, Sung H, Kim MN
- KMID: 2470329
- Ann Lab Med.
- 2020 Jul;40(4):321-325.
- doi: 10.3343/alm.2020.40.4.321
This study investigated resistance mechanisms and epidemiology of emerging linezolid-nonsusceptible Enterococcus faecalis (LNSEF) in a tertiary care hospital. LNSEF isolated from clinical samples were collected from November 2017 to June... -
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- Successful Treatment of Vancomycin-Resistant Enterococcal Peritonitis with linezolid in a Patient on CAPD
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Yoo DE, Kim MK, Huh AJ, Kim YA, Kang EW, Yoo TH, Shin SK
- KMID: 2254059
- Korean J Nephrol.
- 2007 Mar;26(2):289-293.
Peritonitis is one of the major complications of CAPD (continuous ambulatory peritoneal dialysis). Among its causative organisms, vancomycin-resistant enterococcus (VRE) is rare, but serious causative organism, because it is refractory... -
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- Brain Abscess Showing a Lack of Restricted Diffusion and Successfully Treated with Linezolid
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Kim JH, Park SP, Moon BG, Kim DR
- KMID: 2423981
- Brain Tumor Res Treat.
- 2018 Oct;6(2):92-96.
- doi: 10.14791/btrt.2018.6.e16
A 59-year-old patient with a history of hepatocellular carcinoma presented with decreased consciousness and left hemiparesis. A rim-enhanced mass lesion without diffusion restriction was observed in contrast-enhanced MRI including diffusion-weighted... -
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- Efficacy and Tolerability of Linezolid for Treatment of Infectious Spondylitis
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Jung J, Lee E, Song KH, Choe PG, Park WB, Bang JH, Kim ES, Kim HB, Park SW, Kim NJ, Oh MD
- KMID: 2446989
- Korean J Med.
- 2018 Oct;93(5):464-472.
- doi: 10.3904/kjm.2018.93.5.464
BACKGROUND/AIMS: Infectious spondylitis requires long-term antibiotic treatment; however, the use of intravenous antibiotics during this period has high social and monetary costs due to hospitalization. Linezolid has high oral bioavailability... -
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- A Case of Septic Arthritis Caused by Persistent MRSA Bacteremia with Successful Treatment Through Linezolid
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Kim SB, Oh DH, Kim YC, Kim MH, Song JE, Ahn JY, Jeong SJ, Goo NS, Kim HW, Han SH, Choi JY, Song YG, Kim JM
- KMID: 2170389
- Infect Chemother.
- 2012 Oct;44(5):403-406.
- doi: 10.3947/ic.2012.44.5.403
Vancomycin is the primary antibiotic administered for treatment of methicillin-resistant S. aureus (MRSA) infection; however, treatment failure of vancomycin is currently not uncommon in patients with in vitro vancomycin susceptibile... -
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- Linezolid Treatment for Osteomyelitis due to Staphylococcus Epidermidis with Reduced Vancomycin Susceptibility
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Nam JR, Kim MS, Lee CH, Whang DH
- KMID: 2189395
- J Korean Neurosurg Soc.
- 2008 Jun;43(6):307-310.
- doi: 10.3340/jkns.2008.43.6.307
Limited therapeutic options are available for vancomycin intermediate-resistant Staphylococcus Epidermidis (VISE) infections and no optimum therapy has been established. We report a case of VISE skull osteomyelitis that was successfully... -
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- Molecular Epidemiology and Mechanisms of 43 Low-Level Linezolid-Resistant Enterococcus faecalis Strains in Chongqing, China
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Hua R, Xia Y, Wu W, Yang M, Yan J
- KMID: 2420269
- Ann Lab Med.
- 2019 Jan;39(1):36-42.
- doi: 10.3343/alm.2019.39.1.36
BACKGROUND: Enterococcus faecalis strains with low-level resistance to linezolid (an oxazolidinone antibiotic) have become common. No large-scale study has examined the underlying mechanisms in linezolid-resistant E. faecalis (LRE) strains. We... -
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- Susceptibility of Glycopeptide-Resistant Enterococci to Linezolid, Quinupristin/dalfopristin, Tigecycline and Daptomycin in a Tertiary Greek Hospital
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Maraki S, Samonis G, Dimopoulou D, Mantadakis E
- KMID: 2170494
- Infect Chemother.
- 2014 Dec;46(4):253-256.
- doi: 10.3947/ic.2014.46.4.253
We investigated the antibiotic susceptibility of glycopeptide-resistant enterococci (GRE). Seventy consecutive GRE were tested. Sixty-two isolates were identified as Enterococcus faecium (88.6%), and 8 (11.4%) as Enterococcus faecalis. All strains... -
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- Successful Treatment of Recurrent Methicillin-resistant Staphylococcus aureus Bacteremia and Endocarditis by Linezolid, Valve Replacement, and Excisional Surgery of Limb in a Patient with Complicated Arteriovenous Malformation
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Lee K, Kim H, Kim J, Lee G, Lee H, Kim H, Kim D, Sohn I, Pai H
- KMID: 2170323
- Infect Chemother.
- 2010 Dec;42(6):415-419.
- doi: 10.3947/ic.2010.42.6.415
Vancomycin treatment failure in methicillin-resistant Staphylococcus aureus (MRSA) bacteremia patients has increased over the past decade. We experienced a case of repeated MRSA bacteremia resulting in left-side endocarditis in 38-year-old... -
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- Microbiological Characteristics of Corynebacterium striatum, an Emerging Pathogen
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Song SA, Shin JH
- KMID: 2431305
- Hanyang Med Rev.
- 2018 Jun;38(2):93-98.
- doi: 10.7599/hmr.2018.38.2.93
C. striatum is part of the normal skin and mucous membrane flora in humans and is widely disseminated in the environment. Traditionally, these strains have been considered contaminants. However, C.... -
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- Recent Advances in Tuberculosis and Nontuberculous Mycobacteria Lung Disease
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Park JS
- KMID: 2320424
- Tuberc Respir Dis.
- 2013 Jun;74(6):251-255.
Tuberculosis (TB) is one of the largest health problems in the world today. And the incidence of nontuberculous mycobacteria (NTM) lung disease appears to be increasing worldwide. Recently, an automated,... -
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- Antimicrobial therapy for methicillin-resistant Staphylococcus aureus
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Choo EJ
- KMID: 2406975
- J Korean Med Assoc.
- 2018 Mar;61(3):207-213.
- doi: 10.5124/jkma.2018.61.3.207
Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of healthcare-associated infections. Recently, community-associated MRSA has emerged, manifesting as skin and soft tissue infections in patients without any prior healthcare contact.... -
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