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Activating transcription factor 4 aggravates angiotensin IIinduced cell dysfunction in human vascular aortic smooth muscle cells via transcriptionally activating fibroblast growth factor 21

Tao K, Li M, Gu X, Wang M, Qian T, Hu L, Li J

Abdominal aortic aneurysm (AAA) is a life-threatening disorder worldwide. Fibroblast growth factor 21 (FGF21) was shown to display a high level in the plasma of patients with AAA; however, its...
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Feasibility of a Clinical-Radiomics Model to Predict the Outcomes of Acute Ischemic Stroke

Zhou Y, Wu D, Yan S, Xie Y, Zhang S, Lv W, Qin Y, Liu Y, Liu C, Lu J, Li J, Zhu H, Liu WV, Liu H, Zhang G, Zhu W

Objective: To develop a model incorporating radiomic features and clinical factors to accurately predict acute ischemic stroke (AIS) outcomes. Materials and Methods: Data from 522 AIS patients (382 male [73.2%]; mean...
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Psoriatic Serum Induce an Abnormal Inflammatory Phenotype and a Decreased Immunosuppressive Function of Mesenchymal Stem Cells

Wang F, Hou R, Li J, Zhao X, Wang Q, Zhang K, Li X

Background and Objectives: Mesenchymal stem cells (MSCs) have immunomodulatory function and participate in the pathogenesis of many immunoregulation-related diseases, including psoriasis. Previously, we found that MSCs from psoriatic lesions overexpress...
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Association Between Psychosocial Disorders and Gastroesophageal Reflux Disease: A Systematic Review and Meta-analysis

He M, Wang Q, Yao D, Li J, Bai G

  • KMID: 2528035
  • J Neurogastroenterol Motil.
  • 2022 Apr;28(2):212-221.
  • doi: 10.5056/jnm21044
Background/Aims The incidence of gastroesophageal reflux disease (GERD) is increasing annually. Studies have suggested that psychosocial disorders may be linked to the development of GERD. However, studies evaluating the association between...
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Development and Validation of 18F-FDG PET/CT-Based Multivariable Clinical Prediction Models for the Identification of Malignancy-Associated Hemophagocytic Lymphohistiocytosis

Yang X, Lu X, Liu J, Kan Y, Wang W, Zhang S, Liu L, Li J, Yang J

Objective: 18F-fluorodeoxyglucose (FDG) PET/CT is often used for detecting malignancy in patients with newly diagnosed hemophagocytic lymphohistiocytosis (HLH), with acceptable sensitivity but relatively low specificity. The aim of this study...
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Clinicopathological features of non-conventional renal cell carcinoma histological subtypes: Learning points from a large contemporary series spanning over three decades

Lim EJ, Fong KY, Li J, Huang HH, Chen K, Tay KJ, i Sam Cheng CW, Sien Ho HS, Ngo NT, Peng Yuen JS

Purpose: To perform a retrospective review of the clinicopathological features of patients with conventional and non-conventional renal cell carcinoma (cRCC and ncRCC). Materials and Methods: A large prospectively maintained uro-oncological registry...
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A Pilot Study of Clinical Evaluation and Formation Mechanism of Irritable Bowel Syndrome-like Symptoms in Inflammatory Bowel Disease Patients in Remission

Wang H, Zhao X, Cui X, Wang M, Jiao C, Li J, Yang Y, Li Y, Zhang H

  • KMID: 2521167
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):612-625.
  • doi: 10.5056/jnm20151
Background/Aims Some inflammatory bowel disease (IBD) patients in remission suffer from irritable bowel syndrome (IBS)-like symptoms (IBD-IBS). The pathogenesis has not yet been elucidated. The study aim is to evaluate relationships...
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Modified Procedures for ALPPS Based on a Risk-Reduced Strategy: Paralleled Clinical Evaluation at Multiple Institutions

Kong YL, Xing Y, Li J, Liu CL, He XJ, Wang C, Chen JM, Kong LH, Han X, Zhang HY

Purpose: We compared the clinical outcomes of modified procedures for associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) based on a risk-reduced strategy with those of classic...
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Modifiable Risk Factors for Cardiovascular Disease in Korea and Japan

Arafa A, Lee HH, Eshak ES, Shirai K, Liu K, Li J, Anni NS, Shim SY, Kim HC, Iso H

Cardiovascular disease (CVD) is the leading cause of death and a major contributor to disability worldwide. Since the majority of cardiovascular events are preventable, identification of modifiable CVD risk factors...
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Galectin-3 Derived from HucMSC Exosomes Promoted Myocardial Fibroblast-to-Myofibroblast Differentiation Associated with β-catenin Upregulation

Guo Q, Zhao Y, Li J, Huang C, Wang H, Zhao X, Wang M, Zhu W

Background and Objectives: Galectin-3 promotes fibroblast-to-myofibroblast differentiation and facilitates injury repair. Previous studies have shown that exosomes derived from human umbilical cord mesenchymal stem cells (hucMSC-ex) promote the differentiation of...
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Molecular detection and genetic diversity of bovine papillomavirus in dairy cows in Xinjiang, China

Meng Q, Ning C, Wang L, Ren Y, Li J, Xiao C, Li Y, Li Z, He Z, Cai X, Qiao J

Background: Bovine papillomatosis is a type of proliferative tumor disease of skin and mucosae caused by bovine papillomavirus (BPV). As a transboundary and emerging disease in cattle, it poses a...
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Identification of a mimotope of an infectious bronchitis virus S1 protein

Zhou J, Li J, Li Y, Liu H, Qi Y, Wang A

The S1 protein of the infectious bronchitis virus (IBV) is a major structural protein that induces the production of the virus-neutralization antibodies. The monoclonal antibody against the IBV M41 S1...
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Novel reassortant 2.3.4.4B H5N6 highly pathogenic avian influenza viruses circulating among wild, domestic birds in Xinjiang, Northwest China

Zhang Q, Mei X, Zhang C, Li J, Chang N, Aji D, Shi W, Bi Y, Ma Z

Background: The H5 avian influenza viruses (AIVs) of clade 2.3.4.4 circulate in wild and domestic birds worldwide. In 2017, nine strains of H5N6 AIVs were isolated from aquatic poultry in...
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Characterization of Brain Microstructural Abnormalities in High Myopia Patients: A Preliminary Diffusion Kurtosis Imaging Study

Wang H, Wen H, Li J, Chen Q, Li S, Wang Y, Wang Z

Objective: To evaluate microstructural damage in high myopia (HM) patients using 3T diffusion kurtosis imaging (DKI). Materials and Methods: This prospective study included 30 HM patients and 33 age- and sex-matched...
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Intensity of Intraoperative Spinal Cord Hyperechogenicity as a Novel Potential Predictive Indicator of Neurological Recovery for Degenerative Cervical Myelopathy

Chen G, Wei F, Li J, Shi L, Zhang W, Wang X, Xu Z, Liu X, Zou X, Liu S

Objective: To analyze the correlations between intraoperative ultrasound and MRI metrics of the spinal cord in degenerative cervical myelopathy and identify novel potential predictive ultrasonic indicators of neurological recovery for...
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Review of Vasectomy Complications and Safety Concerns

Yang F, Li J, Dong L, Tan K, Huang X, Zhang P, Liu X, Chang D, Yu X

Vasectomy is a simple, safe, effective, and economical method used worldwide for long-term male contraception. As a surgical operation, it has short-term and long-term complications such as hematoma formation, infection,...
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Effect and Mechanism Study of Sodium Houttuyfonate on Ventilator-Induced Lung Injury by Inhibiting ROS and Inflammation

Liu Y, Tang G, Li J

Purpose: Ventilator-induced lung injury (VILI) is a serious complication of mechanical ventilation (MV) that increases morbidity and mortality of patients receiving ventilator treatment. This study aimed to reveal the molecular...
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Xiang Study: an association of breastmilk composition with maternal body mass index and infant growth during the first 3 month of life

Peng X, Li J, Yan S, Chen J, Lane J, Malard P, Liu F

BACKGROUND/OBJECTIVES: This study aimed to establish a mother and child cohort in the Chinese population, and investigate human breastmilk (HBM) composition and its relationship with maternal body mass index (BMI)...
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miRNA-125b Signaling Ameliorates Liver Injury Against Obstructive Jaundice-Induced Excessive Fibrosis in Experimental Rats

Zhang X, Zhang F, Zhang C, Li J

Purpose: Multiple pathways are involved in inducing liver fibrosis, which can damage the integrity of liver. Among them, miR-125b has been found to exert an activating action on hepatic stellate...
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Enhancing immune responses to inactivated foot-and-mouth virus vaccine by a polysaccharide adjuvant of aqueous extracts from Artemisia rupestris L.

Wang D, Yang Y, Li J, Wang B, Zhang A

Background: New-generation adjuvants for foot-and-mouth disease virus (FMDV) vaccines can improve the efficacy of existing vaccines. Chinese medicinal herb polysaccharide possesses better promoting effects. Objectives: In this study, the aqueous extract...
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