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Particulate-Matter Related Respiratory Diseases

Kyung SY, Jeong SH

Particulate matter (PM) is suspended dust that has a diameter of
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The Phosphodiesterase 4 Inhibitor Roflumilast Protects against Cigarette Smoke Extract-Induced Mitophagy-Dependent Cell Death in Epithelial Cells

Kyung SY, Kim YJ, Son ES, Jeong SH, Park JW

BACKGROUND: Recent studies show that mitophagy, the autophagy-dependent turnover of mitochondria, mediates pulmonary epithelial cell death in response to cigarette smoke extract (CSE) exposure and contributes to the development of...
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A Retrospective Study Investigating Risks of Acute Respiratory Distress Syndrome and Mortality Following Human Metapneumovirus Infection in Hospitalized Adults

Hwang H, Kim Y, Park JW, Jeong SH, Kyung SY

BACKGROUND: Human metapneumovirus (hMPV) is a relatively recently identified respiratory virus that induces respiratory symptoms similar to those of respiratory syncytial virus infection in children. The characteristics of hMPV-infected adults...
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Adverse health effects of particulate matter

Kyung SY, Jeong SH

Particulate matter (PM) is known to have serious health effects in individuals with respiratory or cardiovascular disease. Recent studies have shown that they also have noxious effects on cerebrovascular, metabolic,...
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Dust particles-induced intracellular Ca²⁺ signaling and reactive oxygen species in lung fibroblast cell line MRC5

Lee DU, Ji MJ, Kang JY, Kyung SY, Hong JH

Epidemiologic interest in particulate matter (PM) is growing particularly because of its impact of respiratory health. It has been elucidated that PM evoked inflammatory signal in pulmonary epithelia. However, it...
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A Pilot Study of Intralymphatic Immunotherapy for House Dust Mite, Cat, and Dog Allergies

Lee SP, Choi SJ, Joe E, Lee SM, Lee MW, Shim JW, Kim YJ, Kyung SY, Park JW, Jeong SH, Jung JH

Several recent clinical trials reported that intralymphatic immunotherapy (ILIT) for some allergens, such as cat dander and pollen, induce tolerance more rapidly than conventional subcutaneous or sublingual immunotherapy, have a...
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Overlap syndrome with Sjögren’s syndrome and systemic sclerosis in a steel rolling mill worker: a case report

Yi MK, Choi WJ, Han SW, Song SH, Lee DH, Kyung SY, Han SH

BACKGROUND: There are few reports about work-related factors associated with Sjögren’s syndrome. We report a case of overlap syndrome with Sjögren’s syndrome and systemic sclerosis. CASE PRESENTATION: A 54-year-old man was...
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Randomized Phase II Study of Pemetrexed Versus Gefitinib in Previously Treated Patients with Advanced Non-small Cell Lung Cancer

Kim YS, Cho EK, Woo HS, Hong J, Ahn HK, Park I, Sym SJ, Kyung SY, Kang SM, Park JW, Jeong SH, Park J, Lee JH, Shin DB

PURPOSE: This study aimed to evaluate the efficacy and safety of pemetrexed versus gefitinib in patients with advanced non-small cell lung cancer (NSCLC) previously treated with chemotherapy. MATERIALS AND METHODS: Patients...
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Guideline for the prevention and management of particulate matter/Asian dust particle-induced adverse health effect on the patients with pulmonary diseases

Kyung SY, Kim YS, Kim WJ, Park MS, Song JW, Yum H, Yoon HK, Rhee CK, Jeong SH

The aim of this study was to develop guidelines for the prevention and management of particulate matter (PM)/Asian dust particle (ADP)-induced adverse effects in patients with pulmonary diseases. The guideline...
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Annual Change in Pulmonary Function and Clinical Characteristics of Combined Pulmonary Fibrosis and Emphysema and Idiopathic Pulmonary Fibrosis: Over a 3-Year Follow-up

Kim YJ, Shin SH, Park JW, Kyung SY, Kang SM, Lee SP, Sung YM, Kim YK, Jeong SH

  • KMID: 2320533
  • Tuberc Respir Dis.
  • 2014 Jul;77(1):18-23.
BACKGROUND: Combined pulmonary fibrosis and emphysema (CPFE) have different pulmonary function tests (PFTs) and outcomes than idiopathic pulmonary fibrosis (IPF). The intention of this study was to identify unknown differences...
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Asian Dust Particles Induce TGF-beta1 via Reactive Oxygen Species in Bronchial Epithelial Cells

Kyung SY, Yoon JY, Kim YJ, Lee SP, Park JW, Jeong SH

  • KMID: 2319897
  • Tuberc Respir Dis.
  • 2012 Aug;73(2):84-92.
BACKGROUND: Asian dust storms can be transported across eastern Asia. In vitro, Asian dust particle-induced inflammation and enhancement of the allergic reaction have been observed. However, the fibrotic effects of...
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Clinical Characteristics of Idiopathic Pulmonary Fibrosis Patients with Diabetes Mellitus: the National Survey in Korea from 2003 to 2007

Kim YJ, Park JW, Kyung SY, Lee SP, Chung MP, Kim YH, Lee JH, Kim YC, Ryu JS, Lee HL, Park CS, Uh ST, Lee YC, Kim KH, Chun YJ, Park YB, Kim DS, Jegal Y, Lee JH, Park MS, Jeong SH

Evidence suggests that diabetes mellitus (DM) is associated with idiopathic pulmonary fibrosis (IPF). According to the new IPF guidelines, high-resolution computed tomography (HRCT) is an essential means of diagnosing IPF....
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A Case of Scedosporium Apiospermum Pneumonia in an Immunocompetent Patient

Kim YJ, Kim SH, Jeong SH, Park SH, Seo YH, Kyung SY

  • KMID: 2264122
  • Korean J Med.
  • 2011 Nov;81(5):647-651.
Scedosporium apiospermum, an asexual form of Pseudallescheria boydii, is a saprophytic mold with a worldwide distribution. It may cause severe pulmonary or disseminated infections in immunocompromised patients who have undergone...
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A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel

Kyung SY, Cho YK, Kim YJ, Park JW, Jeong SH, Lee JI, Sung YM, Lee SP

Paragonimiasis is an infectious disease caused by trematodes of the genus Paragonimus. This trematode can be treated successfully with praziquantel in more than 90% of the cases. Although praziquantel is...
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A Case of Novel Influenza A (H1N1) Virus Pneumonia Complicated Pnemomediastinum and Subcutenous Emphysema

Kim YJ, Kyung SY, Park JW, Jeong SH, Seo YH, Lee SP

Recently, a novel influenza A (H1N1) has been recognized as the cause of a worldwide respiratory infection outbreak. Although the symptoms of a novel influenza A (H1N1) are usually mild,...
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Pemetrexed versus Gefitinib versus Erlotinib in Previously Treated Patients with Non-Small Cell Lung Cancer

Hong J, Kyung SY, Lee SP, Park JW, Jung SH, Lee JI, Park SH, Sym SJ, Park J, Cho EK, Shin DB, Lee JH

BACKGROUND/AIMS: The efficacy and safety of pemetrexed, gefitinib, and erlotinib administration in previously treated patients with non-small cell lung cancer (NSCLC) were compared. METHODS: The study patients met the following...
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A Case of Bronchiolitis Obliterans after Exposure to Nitrogen Dioxide

Cheon SY, Kim YJ, Kyung SY, Lee SP, Park JW, Jeong SH

  • KMID: 1453992
  • Korean J Occup Environ Med.
  • 2010 Mar;22(1):64-68.
INTRODUCTION: Irritant gases and aerosols are capable of inducing acute, irritant lung injury. Lung injury caused by the inhaling nitrogen dioxide (NO2) has been known as silo-filler's disease in western...
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Clinical characteristics of lung cancer diagnosed from 2006 to 2008: Data from Gachon University Gil Hospital

Park YM, Kim MG, Won IS, Kim Y, Kyung SY, Lee SP, Lee JI, Park JW, Jung SH, Sym SJ, Park J, Cho EK, Shin DB, Lee JH

  • KMID: 2142939
  • Korean J Med.
  • 2010 Feb;78(2):215-221.
BACKGROUND/AIMS: This study examined the clinical characteristics of patients with lung cancer who were diagnosed at the Gachon University of Medicine and Science Gil Hospital from January 2006 to December...
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A Case of Papillary Adenocarcinoma Presenting with Multiple Cysts

Chon S, Kim YJ, Kyung SY, An CH, Lee SP, Park JW, Jeong SH, Cho EK, Sung YM, Kim NR

A 23-year old woman was admitted to our hospital with hemoptysis. The chest X-ray showed reticulonodular opacity and multiple cysts throughout the entire lung field. The chest CT scan revealed...
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A Case of Acute Eosinophilic Pneumonia Associated with Intramuscular Administration of Progesterone Following In Vitro Fertilization

Park SK, Choi BH, Chon SY, Kim YJ, Kyung SY, Lee SP, Jeong SH, Park JW

  • KMID: 2319297
  • Tuberc Respir Dis.
  • 2009 Dec;67(6):556-559.
Acute eosinophilic pneumonia (AEP) is characterized by idiopathic acute febrile illness, diffuse pulmonary infiltration, severe hypoxemia, and pulmonary eosinophilia. We report a case of AEP associated with intramuscular administration of...
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