- Reviewing not Homer’s Iliad, but “Kai Bao Ben Cao”: indigo dye—the past, present, and future
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Yoshimatsu Y, Sujino T, Kanai T
- KMID: 2541889
- Intest Res.
- 2023 Apr;21(2):174-176.
- doi: 10.5217/ir.2022.00018
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- The "Two-Sword Fencing" Technique in Endoscopic Submucosal Dissection
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Nishizawa , Uraoka T, Ochiai Y, Suzuki H, Goto O, Fujimoto A, Maehata T, Kanai T, Yahagi N
- KMID: 2221766
- Clin Endosc.
- 2015 Jan;48(1):85-86.
- doi: 10.5946/ce.2015.48.1.85
No abstract available. -
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- Diet, microbiota, and inflammatory bowel disease: lessons from Japanese foods
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Kanai T, Matsuoka K, Naganuma M, Hayashi A, Hisamatsu
- KMID: 2070102
- Korean J Intern Med.
- 2014 Jul;29(4):409-415.
The incidence and prevalence of inflammatory bowel diseases (IBDs) including ulcerative colitis and Crohn disease are rapidly increasing in Western countries and in developed Asian countries. Although biologic agents targeting... -
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- Current new challenges in the management of ulcerative colitis
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Fukuda T, Naganuma M, Kanai T
- KMID: 2438441
- Intest Res.
- 2019 Jan;17(1):36-44.
- doi: 10.5217/ir.2018.00126
Ulcerative colitis (UC) is a chronic inflammatory condition of the gastrointestinal tract. Although the cause of UC is postulated to be multifactorial in nature, including genetic predisposition, epithelial barrier defects,... -
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- Recent trends in diagnostic techniques for inflammatory bowel disease
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Naganuma M, Hosoe N, Kanai T, Ogata H
- KMID: 2160699
- Korean J Intern Med.
- 2015 May;30(3):271-278.
- doi: 10.3904/kjim.2015.30.3.271
Although ileocolonoscopy is the gold standard for diagnosis of inflammatory bowel disease and is useful for assessing the disease severity in the colon and terminal ileum, several alternative diagnostic techniques... -
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- Efficacy of Slow Nutrient Drinking Test for Evaluating Postprandial Distress Symptom in Japanese Patients With Functional Dyspepsia
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Watanabe T, Masaoka T, Kameyama H, Kanai T
- KMID: 2531216
- J Neurogastroenterol Motil.
- 2022 Jul;28(3):424-430.
- doi: 10.5056/jnm21075
Background/Aims Functional dyspepsia (FD), one of the functional gastrointestinal disorders, is highly prevalent. Impaired gastric accommodation is proposed as a pathophysiology of FD. In order to assess gastric accommodation, a slow... -
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- Risk Factors for Prolonged Hospital Stay after Endoscopy
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Nishizawa T, Yoshida S, Toyoshima O, Matsuno T, Irokawa M, Arano T, Ebinuma H, Suzuki H, Kanai T, Koike K
- KMID: 2522705
- Clin Endosc.
- 2021 Nov;54(6):851-856.
- doi: 10.5946/ce.2020.292
Background/Aims: The recovery room used after endoscopy has limited capacity, and an efficient flow of the endoscopy unit is desired. We investigated the duration of hospital stay after endoscopy and... -
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- Fecal microbiota transplantation for recurrent Clostridium difficile infection in a patient with ulcerative colitis
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Nanki K, Mizuno S, Matsuoka K, Ono K, Sugimoto S, Kiyohara H, Arai M, Nakashima , Takeshita , Saigusa K, Senoh M, Fukuda T, Naganuma M, Kato H, Suda W, Hattori M, Kanai T
- KMID: 2402658
- Intest Res.
- 2018 Jan;16(1):142-146.
- doi: 10.5217/ir.2018.16.1.142
Fecal microbiota transplantation (FMT) has been reported as a safe and effective therapy in patients with refractory and recurrent Clostridium difficile infection (CDI). FMT has also been reported as a... -
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- Effect of elemental diet combined with infliximab dose escalation in patients with Crohn's disease with loss of response to infliximab: CERISIER trial
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Hisamatsu , Kunisaki R, Nakamura S, Tsujikawa , Hirai F, Nakase H, Watanabe K, Yokoyama K, Nagahori M, Kanai T, Naganuma M, Michimae H, Andoh A, Yamada A, Yokoyama T, Kamata N, Tanaka S, Suzuki Y, Hibi T, Watanabe M, CERISIER Trial group
- KMID: 2417663
- Intest Res.
- 2018 Jul;16(3):494-498.
- doi: 10.5217/ir.2018.16.3.494
No abstract available. -
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- 5-Aminosalicylic acid aggravates colitis mimicking exacerbation of ulcerative colitis
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Miyoshi J, Matsuoka K, Yoshida A, Naganuma M, Hisamatsu , Yajima T, Inoue N, Okamoto S, Iwao Y, Ogata H, Ueno F, Hibi T, Kanai T
- KMID: 2434166
- Intest Res.
- 2018 Oct;16(4):635-640.
- doi: 10.5217/ir.2018.00015
Ulcerative colitis (UC) is one of the major clinical phenotypes of inflammatory bowel diseases. Although 5-aminosalicylic acid (5-ASA) is widely used for UC and its efficacy and safety have been... -
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- Colonic dysmotility and morphological abnormality frequently detected in Japanese patients with irritable bowel syndrome
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Mizukami T, Sugimoto S, Masaoka T, Suzuki H, Kanai T
- KMID: 2425167
- Intest Res.
- 2017 Apr;15(2):236-243.
- doi: 10.5217/ir.2017.15.2.236
BACKGROUND/AIMS: Colonoscopy and computed tomography (CT) are used primarily to exclude organic diseases in patients with irritable bowel syndrome (IBS), rather than to assess the pathophysiology of IBS. We aimed... -
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- Ulcerative colitis-associated neoplasms often harbor poor prognostic histologic components with low detection by biopsy
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Sakakibara R, Sugimoto S, Takabayashi K, Kiyohara H, Wakisaka Y, Kaieda Y, Kawaida M, Yoshimatsu Y, Sujino T, Hosoe N, Kato M, Shimoda M, Mikami Y, Iwao Y, Kanai T
- KMID: 2560293
- Intest Res.
- 2024 Oct;22(4):428-438.
- doi: 10.5217/ir.2024.00006
Background/Aims: Poorly differentiated adenocarcinoma, signet-ring cell carcinoma, and mucinous adenocarcinoma (por/sig/muc), which are considered to be histologic subtypes with a poor prognosis, occur more frequently with colitis-associated cancer than with... -
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- Ampullary Adenoma Treated by Endoscopic Double-Snare Retracting Papillectomy
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Soma H, Miyata N, Hozawa S, Higuchi H, Yamagishi , Nakamura Y, Saeki K, Kameyama K, Masugi Y, Yahagi N, Kanai T
- KMID: 2234078
- Gut Liver.
- 2015 Sep;9(5):689-692.
- doi: 10.5009/gnl14206
We report herein improved methods for the safe and successful completion of endoscopic papillectomy (EP). Between January 2008 and November 2011, 12 patients underwent double-snare retracting papillectomy for the treatment... -
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- Effects of the Oral Administration of Mosapride Citrate on Capsule Endoscopy Completion Rate
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Ida Y, Hosoe N, Imaeda H, Bessho R, Ichikawa R, Naganuma M, Kanai T, Hibi T, Ogata H
- KMID: 2053496
- Gut Liver.
- 2012 Jul;6(3):339-343.
BACKGROUND/AIMS: In capsule endoscopy (CE), the capsule does not always reach the cecum within its battery life, which may reduce its diagnostic yield. We evaluated the effect of mosapride citrate,... -
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- Risk of venous thromboembolism with a central venous catheter in hospitalized Japanese patients with inflammatory bowel disease: a propensity score-matched cohort study
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Aoki Y, Kiyohara H, Mikami Y, Nanki K, Kawaguchi T, Yoshimatsu Y, Sugimoto S, Sujino T, Takabayashi K, Hosoe N, Ogata H, Iwao Y, Kanai T
- KMID: 2544755
- Intest Res.
- 2023 Jul;21(3):318-327.
- doi: 10.5217/ir.2022.00116
Background/Aims: Thromboprophylaxis is recommended for hospitalized patients with inflammatory bowel disease (IBD) in Western countries, although it is selectively administered to high-risk patients in East Asia. A central venous catheter... -
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- 5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis
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Mizuno S, Ono K, Mikami Y, Naganuma M, Fukuda T, Minami K, Masaoka T, Terada S, Yoshida T, Saigusa K, Hirahara N, Miyata H, Suda W, Hattori M, Kanai T
- KMID: 2501368
- Intest Res.
- 2020 Jan;18(1):69-78.
- doi: 10.5217/ir.2019.00084
Background/Aims: 5-Aminosalicylic acid (ASA) causes intolerance reactions in some patients. This study was performed to examine the prognosis of patients with ulcerative colitis (UC) and 5-ASA intolerance, and to evaluate... -
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- Role of Enhanced Visibility in Evaluating Polyposis Syndromes Using a Newly Developed Contrast Image Capsule Endoscope
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Hatogai K, Hosoe N, Imaeda H, Rey JF, Okada S, Ishibashi , Kimura K, Yoneno K, Usui S, Ida Y, Tsukada N, Kanai T, Hibi T, Ogata H
- KMID: 2284267
- Gut Liver.
- 2012 Apr;6(2):218-222.
BACKGROUND/AIMS: A flexible spectral imaging color enhancement system was installed in new capsule software for video capsule endoscopy. Contrast image capsule endoscopy (CICE) is a novel technology using light-emitting diodes... -
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- Efficacy of Novel Ultrathin Single-Balloon Enteroscopy for Crohn’s Disease: A Propensity Score-Matched Study
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Takabayashi K, Hosoe N, Kato M, Hayash Y, Miyanaga R, Nanki K, Fukuhara K, Shinta Mizuno YM, Sujino T, Mutaguchi M, Naganuma M, Yahagi N, Ogata H, Kanai T, Mizuno S
- KMID: 2506436
- Gut Liver.
- 2020 Sep;14(5):619-625.
- doi: 10.5009/gnl19228
Background/Aims: The evaluation of small bowel lesions of Crohn’s disease (CD) using balloon-assisted enteroscopy (BAE) is crucial because mucosal healing is associated with a good prognosis. However, BAE procedures are... -
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- Pathophysiology of Potassium-competitive Acid Blocker–refractory Gastroesophageal Reflux and the Potential of Potassium-competitive Acid Blocker Test
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Masaoka T, Kameyama H, Yamane T, Yamamoto Y, Takeuchi H, Suzuki H, Kitagawa Y, Kanai T
- KMID: 2422848
- J Neurogastroenterol Motil.
- 2018 Oct;24(4):577-583.
- doi: 10.5056/jnm18036
BACKGROUND/AIMS: Potassium-competitive acid blockers are expected to be the next generation of drugs for the treatment of diseases caused by gastric acid. In 2015, vonoprazan fumarate, a novel potassium-competitive acid... -
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- Immunological Abnormalities in the Pathogenesis of Inflammatory Bowel Disease
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Hisamatsu , Mikami Y, Matsuoka K, Kanai T, Hibi T
- KMID: 2174247
- Intest Res.
- 2012 Oct;10(4):317-323.
- doi: 10.5217/ir.2012.10.4.317
Crohn's disease and ulcerative colitis represent two distinct forms of inflammatory bowel diseases (IBD). In this paper, we discuss how immunological mechanisms contribute to the pathogenesis of IBD. Intestinal homeostasis... -
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