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A MAST1 Mutation Underlying Mega-Corpus Callosum Syndrome with Extended Phenotypes: The First Case in Korea

Hur YJ, Chung WY, Lim YJ, Park S, Jun KR

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Characteristics of Interstitial Deletion in Chromosome 4q Confirmed by Array Comparative Genomic Hybridization: A Case Report and Literature Review

Chung WY, Lee SJ, Kim HR, Jun KR

Chromosome 4q deletion syndrome is a rare disease caused by partial deletion of the long arm of chromosome 4. Phenotypic severity and expressivity vary among patients with chromosome 4q deletions,...
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Performance Evaluation of MEDITAPE UC-11A Strip Test in Estimating the Urine Albumin-to-Creatinine Ratio and Urine Protein-to-Creatinine Ratio

Yu S, Song SA, Jun KR, Lee JN

BACKGROUND: Proteinuria, including albuminuria, is a primary or major clinical sign of kidney disease. The urine albumin-to-creatinine ratio (UACR) and urine protein-to-creatinine ratio (UPCR) are used to screen patients with...
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Falsely Elevated Tacrolimus Concentrations Using Chemiluminescence Microparticle Immunoassay in Kidney Transplant Patient

Yang D, Song SA, Jun KR, Rim H, Lee W

Tacrolimus is one of the effective immunosuppressive drugs used after an organ transplant procedure. However, due to its narrow therapeutic range, its usefulness in preventing transplant rejection and minimizing nephrotoxicity...
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A Case of Hemolytic Transfusion Reaction Attributable to Anti-Jk(b) Abolished in the Enzyme Phase Reaction

Song SA, Oh SH, Lee JY, Sung SK, Shin JH, Kim HR, Jun KR, Lee JN

We report a case of an intravascular hemolytic reaction attributable to anti-Jk(b) antibodies that were not detected using an enzyme phase antibody identification test. A 61-year-old male who had received...
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Evaluation of the Automated Hematology Analyzer Sysmex XN-2000 and the Accuracy of Differential Leukocyte Counts Using the Low WBC Mode

Lee JY, Song SA, Oh SH, Shin JH, Kim HR, Jun KR, Lee JN

BACKGROUND: The XN-series (Sysmex, Japan) is the new hematology analyzer from Sysmex, with new channels to improve the accuracy of differential leukocyte count and platelet count in the low cell...
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Comparison of the Clinical Performance of Binax NOW RSV Versus Multiplex RT-PCR for Detection of Respiratory Syncytial Virus

Son JA, Kim SH, Shin JH, Jeon GW, Sin JB, Lee JY, Kim HR, Jun KR, Lee JN, Song SA

BACKGROUND: Respiratory syncytial virus (RSV) is one of the most important causes of lower respiratory tract infection. The rapid antigen test is a simple, cheap, and quick method for RSV...
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Clinical Significance of Clonal Rearrangement of the Immunoglobulin Gene in the Bone Marrow of Patients with B-cell Non-Hodgkin Lymphoma

Kim JH, Lee JY, Son JA, Song SA, Oh SH, Shin JH, Kim HR, Jun KR, Lee JN

BACKGROUND: In the early stages of non-Hodgkin lymphoma (NHL), it can be difficult to recognize minimal morphological changes in the bone marrow (BM). In particular, when the quality of the...
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Postsurgical Wound Infection Caused by Mycobacterium conceptionense Identified by Sequencing of 16S rRNA, hsp65, and rpoB Genes in an Immunocompetent Patient

Lee JY, Kim SH, Shin JH, Lee HK, Lee YM, Song SA, Bae IK, Kim CK, Jun KR, Kim HR, Lee JN, Chang CL

Rapidly growing mycobacteria are ubiquitous in the environment and are increasingly being recognized as opportunistic pathogens. Recently, a new species, Mycobacteium conceptionense, has been validated from the Mycobacterium fortuitum third...
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Detection of Anti-Lua in an Unexpected Antibody Screening Test: A Case Report and Literature Review

Song SA, Oh SH, Park TS, Son HS, Sung SK, Lee JY, Jun KR, Shin JH, Kim HR, Lee JN

  • KMID: 2115927
  • Korean J Blood Transfus.
  • 2012 Aug;23(2):169-172.
Lutheran a antigen (Lua) is detected in 6 to 8% of Caucasians and Africans. In Korean and other Asian populations, it is very rare or nearly absent. Therefore, although Lua...
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Autoimmune Hemolytic Anemia after Aplastic Crisis due to Parvovirus B19 Infection in a Patient with Hereditary Spherocytosis

Song SA, Lee MY, Kim SH, Lee JY, Oh SH, Shin JH, Kim HR, Jun KR, Lee JN

  • KMID: 2312200
  • Lab Med Online.
  • 2012 Jul;2(3):166-169.
Hereditary spherocytosis (HS) is a genetic disorder characterized by the production and destruction of spherocytes due to a deficiency of red cell membrane cytoskeletal proteins, resulting in the clinical presentation...
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Three-way Translocation of MLL/MLLT3, t(1;9;11)(p34.2;p22;q23), in a Pediatric Case of Acute Myeloid Leukemia

Jun KR, Lee JN, Park JA, Kim HR, Shin JH, Oh SH, Lee JY, Song SA

The chromosome band 11q23 is a common target region of chromosomal translocation in different types of leukemia, including infantile leukemia and therapy-related leukemia. The target gene at 11q23, MLL, is...
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Identification of a Novel Deletion Region in 3q29 Microdeletion Syndrome by Oligonucleotide Array Comparative Genomic Hybridization

Seo EJ, Jun KR, Yoo HW, Yoo HK, Lee JO

BACKGROUND: The 3q29 microdeletion syndrome is a genomic disorder characterized by mental retardation, developmental delay, microcephaly, and slight facial dysmorphism. In most cases, the microdeletion spans a 1.6-Mb region between...
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Prognostic Significance of TEL/AML1 Rearrangement and Its Additional Genetic Changes in Korean Childhood Precursor B-Acute Lymphoblastic Leukemia

Chung HY, Kim KH, Jun KR, Jang S, Park CJ, Chi HS, Im HJ, Seo JJ, Seo EJ

BACKGROUND: TEL (ETV6)/AML1 (RUNX1) rearrangement is observed in approximately 20-25% of childhood precursor B-ALL and is associated with a favorable outcome. Additional genetic changes, associated with TEL/AML1, are frequently found....
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Factors Affecting the Difference between the Low-Density Lipoprotein Cholesterol Concentrations Measured Directly and Calculated Using the Friedewald Formula

Min WK, Park HI, Jun KR, Chun S, Lee W

  • KMID: 2040471
  • J Lab Med Qual Assur.
  • 2008 Dec;30(2):233-235.
BACKGROUND: National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) is the guideline for detection evaluation, and treatment of high blood cholesterol in adults. The risk of coronary...
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A Case of Beauveria bassiana Keratitis

Jun KR, Jang MS, Park SJ, Kim MN, Kim DY, Tchah H, Kim MJ

  • KMID: 2224742
  • Korean J Clin Microbiol.
  • 2007 Apr;10(1):73-76.
Beauveria bassiana is a hyaline Hypomycetes, which is known as an insect pathogen causing infections in silkworm. It is a rare opportunistic pathogen of human accounted for pulmonary infection, keratitis,...
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Relationship between In Vitro Chemosensitivity assessed with MTT Assay and Clinical Outcomes in 103 Patients with Acute Leukemia

Jun KR, Jang S, Chi HS, Lee KH, Lee JH, Choi SJ, Seo JJ, Moon HN, Im HJ, Park CJ

BACKGROUND: Cellular drug resistance is supposed to play a major role in chemotherapy failure or relapse. The purpose of this study was to analyze the relationship between in vitro...
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Meta-analysis of the Association between HLA-DRB1 Allele and Rheumatoid Arthritis Susceptibility in Asian Populations

Jun KR, Choi SE, Cha CH, Oh HB, Heo YS, Ahn HY, Lee KJ

The aims of this study were to summarize results on the association of HLA-DRB1 with rheumatoid arthritis (RA) in Asians and to determine if the shared epitope (SE) hypothesis could...
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Evaluation of the Phoenix System for the Detection of Methicillin-Resistent Staphylococcus aureus

Jun KR, Jeon HS, Sung H, Kim MN

  • KMID: 2146992
  • Korean J Clin Microbiol.
  • 2006 Apr;9(1):58-63.
BACKGROUND: We evaluated the BD Phoenix Automated Microbiology System (Phoenix) for its ability to detect methicillin resistant Staphylococcus aureus (MRSA) and compared the results to those obtained by the Clinical...
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Clinical Significance of Low-colony Count Scotochromogen Nontuberculous Mycobacteria

Lee JY, Kim MN, Chung HJ, Jun KR, Choi HJ, Lee H, Joung EY, Oh YM, Lee SD, Kim WS, Kim DS, Kim WD, Shim TS

  • KMID: 2318636
  • Tuberc Respir Dis.
  • 2005 Jul;59(1):39-46.
BACKGROUND: Even though it has been suggested that low-colony, scotochromogen nontuberculous mycobacteria (NTM) are usually contaminants and not true pathogens, evidence for this hypothesis has not been provided. This study...
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