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Drug Fever Due to Piperacillin/Tazobactam Loaded into Bone Cement

Park HB, Choi JS, Park SH, Kee WJ, Koh YI

Although drug fever may develop after administration of the drug by various routes, it has not been reported with antibiotic-loaded bone cement. Here, a case of drug fever induced by...
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Incontinentia Pigmenti in a Newborn with NEMO Mutation

Lee Y, Kim S, Kim K, Chang M

Incontinentia pigmenti (IP) (OMIM #308300) is a rare X-linked dominant neuroectodermal multisystemic syndrome due to mutations in the gene for NF-kappaB essential modulator (NEMO). A term newborn girl who was...
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Haddad Syndrome with PHOX2B Gene Mutation in a Korean Infant

Lee CW, Lee JH, Jung EY, Choi SO, Kim CS, Lee SL, Kim DK

Congenital central hypoventilation syndrome with Hirschsprung's disease, also known as Haddad syndrome, is an extremely rare disorder with variable symptoms. Recent studies described that congenital central hypoventilation syndrome had deep...
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GSTM1 Tissue Genotype as a Recurrence Predictor in Non-muscle Invasive Bladder Cancer

Ha YS, Yan C, Jeong P, Kim WT, Yun SJ, Yi Kim I, Moon SK, Kim WJ

Tissue genotyping is more useful approach than using blood genomic DNA, which can reflect the effects of the somatic mutations in cancer. Although polymorphisms in glutathione S-transferase (GST) have been...
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Effects of Benzo(a)pyrene on the Expression of Heat Shock Proteins, Pro-inflammatory Cytokines and Antioxidant Enzymes in Hepatic Tumors Induced by Rat Hepatoma N1-S1 Cells

Zheng Z, Park SY, Lee M, Phark S, Won NH, Kang HS, Sul D

Benzo(a)pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that is easily introduced to humans via consumption of grilled or smoked meat. BaP causes harmful oxidative effects on cell development, growth...
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DNA Methylation Changes Following 5-azacitidine Treatment in Patients with Myelodysplastic Syndrome

Tran HT, Kim HN, Lee IK, Kim YK, Ahn JS, Yang DH, Lee JJ, Kim HJ

DNA methyltransferase inhibitor, 5-azacitidine (AC) is effective in myelodysplastic syndromes (MDS) and can induce re-expression in cancer. We analyzed the methylation of 25 tumor suppressor genes in AC-treated MDS. Hypermethylation...
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The Correlation between Thyrotropin and Dyslipidemia in a Population-based Study

Lu L, Wang B, Shan Z, Jiang F, Teng X, Chen Y, Lai Y, Wang J, Xue H, Wang S, Li C, Liu H, Li N, Yu J, Shi L, Hou X, Xing Q, Bai X, Teng W

This study investigated the relationship between serum thyrotrophin levels and dyslipidemia in subclinical hypothyroid and euthyroid subjects. A total of 110 subjects with subclinical hypothyroidism and 1,240 euthyroid subjects enrolled...
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Catheter-related Candidemia Caused by Candida haemulonii in a Patient in Long-term Hospital Care

Kim S, Ko KS, Moon SY, Lee MS, Lee MY, Son JS

Candida haemulonii, one of the non-albicans Candida species, is an emerging yeast pathogen that is known to be resistant to amphotericin B and other antifungal agents such as azoles. These...
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Extranodal Interdigitating Dendritic Cell Sarcoma Presenting in the Pleura: A Case Report

Han HS, Lee OJ, Lim SN, An JY, Lee KM, Choe KH, Lee KH, Kim ST

Interdigitating dendritic cell sarcoma (IDCS) is an extremely rare neoplasm arising from the antigen-presenting cells of the immune system. This disease usually involves the lymph nodes, and rarely, extranodal sites...
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Predictive Accuracy of a Health Risk Appraisal Program Using Mortality Risk Age in 116,927 Korean Men

Kim JY, Park BJ, Kim Y, Park JH, Cho BL

Health risk appraisal (HRA) is a tool for determining health risk factors and motivating individuals to maintain a healthy lifestyle. We performed this study to describe the HRA algorithm and...
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Endobronchial Ultrasound-guided Transbronchial Needle Biopsy for Diagnosis of Mediastinal Lymphadenopathy in Patients with Extrathoracic Malignancy

Park J, Jang SJ, Park YS, Oh YM, Shim TS, Kim WS, Choi CM

Mediastinal lymphadenopathy associated with extrathoracic malignancy or a metastasis of unknown origin (MUO) requires pathological verification. Surgical exploration or endoscopic ultrasound-guided fine needle aspiration is limited to application. We investigated...
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The Risk of Obstructive Lung Disease by Previous Pulmonary Tuberculosis in a Country with Intermediate Burden of Tuberculosis

Lee SW, Kim YS, Kim DS, Oh YM, Lee SD

We evaluated the effects of previous pulmonary tuberculosis (TB) on the risk of obstructive lung disease. We analyzed population-based, the Second Korea National Health and Nutrition Examination Survey 2001. Participants...
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Prevalence of Allergic Diseases and Risk Factors of Wheezing in Korean Military Personnel

Lee SM, Ahn JS, Noh CS, Lee SW

The objective of this study was to evaluate the prevalence of asthma, allergic rhinitis, and atopic dermatitis, as well as the risk factors of wheezing among young adults in the...
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Trends in Epidemiology of Neonatal Sepsis in a Tertiary Center in Korea: A 26-Year Longitudinal Analysis, 1980-2005

Shim GH, Kim SD, Kim HS, Kim ES, Lee HJ, Lee JA, Choi CW, Kim EK, Choi EH, Kim BI, Lee HJ, Choi JH

There were many reports of longitudinal changes in the causative organisms of neonatal sepsis in Western countries but few in Asia. We aimed to study longitudinal trends in the epidemiology...
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Respiratory Health among Korean Pupils in Relation to Home, School and Outdoor Environment

Kim JL, Elfman L, Wieslander G, Ferm M, Toren K, Norback D

There are few studies about school-environment in relation to pupils' respiratory health, and Korean school-environment has not been characterized. All pupils in 4th grade in 12 selected schools in three...
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Incidence and Risk Factors of Steroid-induced Diabetes in Patients with Respiratory Disease

Kim SY, Yoo CG, Lee CT, Chung HS, Kim YW, Han SK, Shim YS, Yim JJ

Glucocorticoids are effective for treating several respiratory diseases. However, they can cause hyperglycemia. This study determined the incidence and risk factors of steroidinduced diabetes mellitus (S-DM) in patients treated with...
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Role of Corticotrophin-releasing Factor in the Stress-induced Dilation of Esophageal Intercellular Spaces

Cho YJ, Kim JH, Yim HE, Lee DM, Im SK, Lee KJ

Corticotrophin-releasing factor (CRF) plays a major role in coordinating stress responses. We aimed to test whether blocking endogenous CRF activity can prevent the stress-induced dilation of intercellular spaces in esophageal...
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Gender Differences in the Effect of Obesity on Chronic Diseases among the Elderly Koreans

Kim IH, Chun H, Kwon JW

The objective of this study is to investigate gender differences of obesity on major chronic diseases in elderly Korean males and females. This study applied a cross sectional design using...
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Malignancy Rate in Sonographically Suspicious Thyroid Nodules of Less than a Centimeter in Size Does Not Decrease with Decreasing Size

Bo YH, Ahn HY, Lee YH, Lee YJ, Kim JH, Ohn JH, Hong ES, Kim KW, Jeong IK, Choi SH, Lim S, Park DJ, Jang HC, Oh BH, Cho BY, Park YJ

We evaluated the malignancy and nondiagnostic rates using fine needle aspiration cytology (FNAC) results in thyroid nodules smaller than 1 cm according to the subdivided size. We retrospectively reviewed the...
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Could HBx Protein Expression Affect Signal Pathway Inhibition by Gefitinib or Selumetinib, a MEK Inhibitor, in Hepatocellular Carcinoma Cell Lines?

Park YK, Kim KM, Lee YJ, Kim KH, Lee SG, Lee D, Shim JH, Lim YS, Lee HC, Chung YH, Lee YS, Suh DJ

Hepatitis B virus X (HBx) protein has been known to play an important role in development of hepatocellular carcinoma (HCC). The aim of this study is to find out whether...
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