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Angiolipoma of the Breast: A Case Report

Kim SY, Kim HH, Kim EH, Kim SY, Jou SS, Han JK, Kim YT

An angiolipoma is a common mixed connective tissue tumor that commonly occurs in the trunk and extremities, and has been rarely reported in the breast. It is a benign variant...
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Experience with Intracystic Papillary Carcinoma of the Breast at a Single Institute in Korea

Lee SK, Choi JH, Lim HI, Kim WW, Kim S, Cho EY, Choe JH, Kim JH, Kim JS, Nam SJ, Yang JH, Lee JE

Intracystic papillary carcinoma (IPC) of the breast is a rare entity, which can be associated with ductal carcinoma in situ (DCIS) or an invasive carcinoma. There have been only limited...
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Changes in the Hormone Receptors and the HER2 Expression in Primary and Recurrent Breast Cancer

Choi JP, Son BH, Ahn SH, Kim HJ, Lee JW, Lim W, Soe JY, Ko BS, Lee YM, Kwon SB, Gong GY

PURPOSE: This study aimed at evaluating the pattern of changes in estrogen receptor (ER), progesterone receptor (PR) and the HER2 expression in primary and recurrent breast cancer. METHODS: In the...
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Factors Affecting the Ipsilateral Breast Tumor Recurrence after Breast Conserving Therapy in Patients with T1 and T2 Tumors

Kim JH, Han W, Moon HG, Ko E, Lee JW, Kim EK, Park IA, Ha SW, Chie EK, Oh SK, Youn YK, Kim SW, Hwang KT, Noh DY

PURPOSE: Nearly half of all breast cancers are treated with breast conserving therapy (BCT). The purpose of this study was to identify the risk factors for ipsilateral breast tumor recurrence...
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The Influence of Breast Volume on Prognosis of Primary Breast Cancer with Same T Stage

Lee JJ, Jeon YS, Kang SH, Lee SJ

PURPOSE: The aim of this study was to evaluate the prognostic significance of the breast volume in primary breast cancer patients with the same T stage. METHODS: The study population...
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The Clinical Significance of Diffuse Thyroid Uptake That is Incidentally Identified by F-18 FDG PET/CT Imaging in Patients with Breast Cancer

Jeong YJ, Lim ST, Kim DW, Jeong HJ, Youn HJ, Jung SH, Sohn MH

PURPOSE: This study was to investigate the clinical significance of diffusely increased F-18 FDG uptake in the thyroid gland as an incidental finding on F-18 FDG PET/CT imaging in patients...
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Risk Factors of Local Recurrence after Breast Conserving Therapy in Invasive Breast Cancer

Yi OV, Lee JW, Kim HJ, Lim WS, Park EH, Lee JS, Son BH, Gong G, Ahn SD, Ahn SH

PURPOSE: Twenty-year follow-up results of two pioneering randomized controlled trials have demonstrated equal patient survival after mastectomy and breast conservation therapy. The use of breast conservation therapy has undoubtedly provided...
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The Comparison of Automated Silver in situ Hybridization and Fluorescence in situ Hybridization for Evaluating HER2 Gene Amplification in Breast Carcinoma

Kim TJ, Kim TE, Jung ES, Yim HW, Song BJ, Jung SS, Lee A, Choi YJ, Lee KY

PURPOSE: We want to validate the use of the silver-enhanced in situ hybridization (SISH) technique as comparised with fluorescence in situ hybridization (FISH) technique for assessing the HER2 gene amplification...
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The Prognostic Significance of Survivin Expression in Breast Cancer

Oh JW, Yang WI, Lee MJ, Park S, Park BW, Lee KS

PURPOSE: Survivin is a member of the inhibitors of apoptosis family. It has recently comes into the limelight as a promising tumor marker, but many previous reports have shown controversial...
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Phase II Study of Vinorelbine Plus Ifosfamide in Patients with Taxane-resistant Metastatic Breast Cancer

Lee S, Oh SY, Kwon HC, Kim SH, Kwon KA, Hsing CT, Kim DC, Lee JH, Lee HS, Lee MR, Cho SH, Kim HJ

PURPOSE: The patients with metastatic breast cancer are routinely exposed to taxane and anthracycline as neoadjuvant, adjuvant, and palliative chemotherapeutic agents. This study was designed to evaluate the efficacy and...
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Arm Sentinel Lymph Node Detection for Preserving the Arm Lymphatic System

Lee SK, Choi JH, Lim HI, Kim WW, Kim S, Choe JH, Lee JE, Kim JH, Kim JS, Nam SJ, Yang JH

PURPOSE: The objective of arm sentinel lymph node (SLN) detection were to identify the presence of different drainage tracts of the breast and arm lymphatics and eventually to prevent lymphedema...
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A Comparison of Outcomes for the Patients with Pathologically Node-negative Breast Cancer and Who Were Treated Either with Sentinel Lymph Node Biopsy Only or with Conventional Axillary Lymph Node Dissection

Kim HA, Jo EJ, Kim MS, Kim YH, Paik NS, Moon NM, Lee JI, Yang KM, Noh WC

PURPOSE: False negative results obtained with the use of a sentinel lymph node biopsy (SLNB) can result in down staging of tumors, whereas the use of a more elaborated pathological...
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Validation of Radiation Volume by Analysis of Recurrence Pattern in Breast-conserving Treatment for Early Breast Cancer

Shim SJ, Kim YB, Keum KC, Lee IJ, Lee HD, Suh CO

PURPOSE: To assess the appropriateness of radiotherapy volume for patients receiving breast-conserving treatment (BCT) through analysis of recurrence pattern and factors affecting recurrence. METHODS: From 1991 to 1996, 362 patients...
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Expression of CXCR4 and SDF-1alpha in Primary Breast Cancers and Metastatic Lymph Nodes

Kim JO, Suh KS, Lee DH, Sul HJ, Lee JU, Song KS

PURPOSE: A CXCR4/stroma derived factor-1alpha (SDF-1alpha, CXCL12) interaction is involved in many metastatic cancer mechanisms, including breast cancer. The primary objectives of this study were to investigate the correlation between...
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Comparison between Therapeutic Efficacies of Histone Deacetylase Inhibitors and Established Drug Regimens Against Breast Cancer Cells using the Histoculture Drug Response Assay

Seo JY, Lee YM, Cho DH, Roh SA, Ro SG, Hyun YL, Kim SY, Kim YS, Kim TW, Ahn SH, Kim JC

PURPOSE: Histone deacetylase inhibitors (HDACIs) induce accumulation of acetylated histones in nucleosomes, which lead to reactivate gene expression and inhibit the growth and survival of tumor cells. This study evaluated...
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Comparison of Silver-Enhanced in situ Hybridization and Fluorescence in situ Hybridization for HER2 Gene Status in Breast Carcinomas

Kang J, Kwon GY, Lee YH, Gong G

PURPOSE: Silver-enhanced in situ hybridization (SISH) is a newly developed method to evaluate HER2 gene amplification in invasive breast carcinomas. Most laboratories widely use fluorescence in situ hybridization (FISH) to...
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Molecular Targets for Treatment of Breast Cancer

Park WC, Kim LS, Kim TH, Park BW, Park HY, Song BJ, Lee JB, Jeon CW, Choi UJ

Advances in molecular biology have made it possible to understand the tumor biology of breast cancer at the molecular level and have revealed molecular targets for the therapy of breast...
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