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Molecular Characterization of sca Genes Found in Orientia tsutsugamushi Genome

Ha NY, Choi MS, Cho NH

Scrub typhus is an acute, febrile illness caused by Orientia tsutsugamushi infection and it is one of the main causes of acute febrile illness in the Asian-Pacific region. The incidence...
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Current Understanding of HMGB1-mediated Autophagy

Kwak MS, Shin JS

Reactive oxygen species (ROS) is an oxidative stress to which cells respond by activating various defense mechanisms or cell death. Autophagy associated with oxidative stress response is a process to...
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PKR as a Regulator of Inflammasome Activation

Manzoor Z, Koh YS

Detection of pathogen by pattern recognition receptors leads to activation of inflammasome which plays a crucial role in immune system. The inflammasome regulates the release of cytokines, such as interleukin...
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An Epidemiological Survey on Serological Diagnosis of Legionnella Infection in Seoul, Korea

Yoon YT, Han CH, Choi SS, Lee JM, Kim CK, Choi SM

Serological investigation of antibodies to Legionella species in 1,802 sera collected in seoul was conducted with indirect fluorescent antibody assay (IFA). With an antibody titer of > or =1:128 to...
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Study of the Detection of Enteric Viruses and Bacteria in Spring-water and Groundwater in Busan ('10~'11)

Choi SH, Jeong JE, Yun NN, Kim NH, Park YK, Jung EY

We analyzed the occurrence of enteric viruses and bacteria at 22 places of drinkable groundwater (civil defense emergency water-supply facility), 8 places of the groundwater used for drinking water in...
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The Synergistic Effects of Antimicrobial Peptides on the Growth Inhibition of Salmonella Typhimurium through Imd Pathway in Drosophila Intestine

Lim YJ, Jo YH, Kim HJ, Park JK

Some Bacillus species present in fermented foods are regarded as probiotics because of their ability to modulate the prevention of some intestinal infections and the modulation of the inflammatory immune...
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Molecular Typing of Cryptococcus neoformans Isolated from Korean Patients

Park SH, Cho SI, Hwang SM

Cyptococcosis is generally caused by Cryptococcus neoformans, the opportunistic agent which has two species such as C. neoformans and C. gattii. Both C. neoformans and C. gattii species contain a...
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Characterization of Community-Associated Methicillin-Resistant Staphylococcus aureus in Gwangju, Korea

Kee HY, Kim MJ, Kim SH, Lee SM, Kim SK, Ha DR, Kim ES, Chung JK

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most important nosocomial pathogens worldwide. This study was performed to investigate the characterization of MRSA isolated from healthy persons in Gwangju area....
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Nucleoside Diphosphate Kinase from Microorganisms

Choi CH

Nucleoside diphosphate kinase (Ndk) is ubiquitous and highly conserved multifunctional key enzyme in nucleotide metabolism. It generates nucleoside triphosphates (NTPs) by transfer of gamma-phosphates from nucleoside triphosphates such as ATP...
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Cell Death and Bacterial Infection

Song CH

Cells can die through various biochemical pathways related to complex pathophysiological process. Different types of cell death are closely associated with microbial infection. Several regulatory mechanisms of cell death during...
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Sensing DNA Viruses and Bacteria by Intracellular DNA Sensors

Lee NR, Shin HB, Kim HI, Choi MS, Inn KS

The innate immune system confers first-line defense against various pathogens including bacteria and viruses. Early detection of invading pathogens by the host depends on a limited number of specific pattern...
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