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Tacrolimus in pediatric ulcerative colitis: does it have a role?

Kim S

No abstract available.
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Importance of nutritional therapy in the management of intestinal diseases: beyond energy and nutrient supply

Kim SE

The gut is an immune-microbiome-epithelial complex. Gut microbiome-host interactions have widespread biological implications, and the role of this complex system extends beyond the digestion of food and nutrient absorption. Dietary...
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Stroke and neck bruit in a boy with Crohn’s disease

Tomiyama R, Hokama A, Koga E, Shimabukuro K, Oishi Y, Ohira T, Iraha A, Kinjo T, Fujita J

No abstract available.
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Is fecal calprotectin always normal in children with irritable bowel syndrome?

Choi YJ, Jeong SJ

BACKGROUND/AIMS: Fecal calprotectin (FC) is a marker of intraluminal intestinal inflammation. Intestinal inflammation may contribute to the pathophysiology of irritable bowel syndrome (IBS). This study evaluated FC levels in children...
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Nutritional issues in patients with cancer

Kim DH

Cancer is a catabolic inflammatory disease that causes patients to often experience weight loss, or even cachexia in severe cases. Undernourishment in patients with cancer impairs the quality of life...
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Primary malignant melanoma without melanosis of the colon

Yi NH, Lee JW, Lee SH, Kim JH, Jee SR, Seol SY

Primary malignant melanoma (PMM) of the gastrointestinal tract is rare. Reported cases of PMM of the lower gastrointestinal tract typically describe anal and rectal involvement rather than colonic lesions. This...
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Nutritional approach as therapeutic manipulation in inflammatory bowel disease

Yoon JY

Malnutrition is observed more frequently in patients with inflammatory bowel disease (IBD) than in the general population and associated with adverse clinical outcomes. This study aimed to review the current...
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Parthenolide inhibits transforming growth factor β1-induced epithelial-mesenchymal transition in colorectal cancer cells

Zhu SM, Park YR, Seo SY, Kim IH, Lee ST, Kim SW

BACKGROUND/AIMS: Transforming growth factor-β1 (TGF-β1) induction of epithelial-mesenchymal transition (EMT) is one of the mechanisms by which colorectal cancer (CRC) cells acquire migratory and invasive capacities, and subsequently metastasize. Parthenolide...
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Polypharmacy is a risk factor for disease flare in adult patients with ulcerative colitis: a retrospective cohort study

Wang J, Nakamura T, Tuskey AG, Behm BW

BACKGROUND/AIMS: Polypharmacy is a common clinical problem with chronic diseases that can be associated with adverse patient outcomes. The present study aimed to determine the prevalence and patient-specific characteristics associated...
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Frequency and intensity of gastrointestinal symptoms in exercisers individuals at rest and during physical exercise: an internet-based survey

de Lira CA, Viana RB, Mesquista , Santos DD, Campos MH, Andrade MS, Vancini RL

BACKGROUND/AIMS: Despite the evidence of a modest to high prevalence of gastrointestinal (GI) symptoms in recreational runners and endurance athletes, the frequency and intensity of GI symptoms in exercisers, but...
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Familial aggregation of inflammatory bowel disease in India: prevalence, risks and impact on disease behavior

Banerjee R, Pal P, Hutfless S, Ganesh BG, Reddy DN

BACKGROUND/AIMS: Information about familial aggregation of inflammatory bowel disease (IBD) in Asia is limited. We aimed to analyze the prevalence and risk of familial IBD in an Indian cohort and...
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Infliximab biosimilar CT-P13 is interchangeable with its originator for patients with inflammatory bowel disease in real world practice

Nakagawa T, Kobayashi , Nishikawa , Yamada F, Asai S, Sameshima , Suzuki Y, Watanabe M, Hibi T

BACKGROUND/AIMS: An interim analysis of post-marketing surveillance of CT-P13, an infliximab biosimilar, was performed to evaluate its safety and efficacy in Japanese patients with inflammatory bowel disease. METHODS: Patients were prospectively...
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Clinical outcomes of positive resection margin after endoscopic mucosal resection of early colon cancers

Park J, Kim HG, Jeong SO, Jo HG, Song HY, Kim J, Ryu S, Cho Y, Youn HJ, Jeon SR, Kim JO, Ko BM, Jeen YM, Jin SY

BACKGROUND/AIMS: When determining the subsequent management after endoscopic resection of the early colon cancer (ECC), various factors including the margin status should be considered. This study assessed the subsequent management...
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Primary epiploic appendagitis: compared with diverticulitis and focused on obesity and recurrence

Choi YI, Woo HS, Chung JW, Shim YS, Kwon KA, Kim KO, Kim YJ, Park DK

BACKGROUND/AIMS: There is limited data to compare the clinical characteristics and recurrence rates between left-sided primary epiploic appendagitis (PEA) versus left-sided acute colonic diverticulitis (ACD), and right-sided PEA versus right-sided...
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Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan

Yanagi T, Ushijima K, Koga H, Tomomasa T, Tajiri H, Kunisaki R, Isihige T, Yamada H, Arai K, Yoden A, Aomatsu T, Nagata S, Uchida K, Ohtsuka Y, Shimizu T

BACKGROUND/AIMS: Tacrolimus is effective for refractory ulcerative colitis in adults, while data for children is sparse. We aimed to evaluate the effectiveness and safety of tacrolimus for induction and maintenance...
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