- Vascularized Organoids: A More Complete Model
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Yu J
- KMID: 2515990
- Int J Stem Cells.
- 2021 May;14(2):127-137.
- doi: 10.15283/ijsc20143
As an emerging research model in vitro, organoids have achieved major progress in recapitulating morphological aspects of organs and personalized precision therapy. Various organoids have been currently constructed in vitro... -
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- Inhibition of MUC1-C Increases ROS and Cell Death in Mouse Embryonic Stem Cells
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Park JA, Park S, Choi JK, Han MK, Lee Y
- KMID: 2515994
- Int J Stem Cells.
- 2021 May;14(2):180-190.
- doi: 10.15283/ijsc20089v
Background and Objectives: Embryonic stem (ES) cells have the capacity to self-renew and generate all types of cells. MUC1-C, a cytoplasmic subunit of MUC1, is overexpressed in various carcinomas and mediates... -
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- Organoids: A New Model for SARS-CoV-2 Translational Research
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Yu J
- KMID: 2515991
- Int J Stem Cells.
- 2021 May;14(2):138-149.
- doi: 10.15283/ijsc20169
The 2019-novel coronavirus (SARS-CoV-2) pneumonia epidemic is a thorny public health problem faced by health officials and a major cause of concern for health professionals. However, the currently used immortalized... -
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- Mesenchymal Stem Cell and MicroRNA Therapy of Musculoskeletal Diseases
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Chung MJ, Son JY, Park S, Park SS, Hur K, Lee SH, Lee EJ, Park JK, Hong IH, Kim TH, Jeong KS
- KMID: 2515992
- Int J Stem Cells.
- 2021 May;14(2):150-167.
- doi: 10.15283/ijsc20167
The therapeutic effects of mesenchymal stem cells (MSCs) in musculoskeletal diseases (MSDs) have been verified in many human and animal studies. Although some tissues contain MSCs, the number of cells... -
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- Optimal Hypoxic Preconditioning of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells (hES-MSCs) and Their Characteristics
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Lee SM, Jun DW, Kang HT, Oh JH, Saeed WK, Ahn SB
- KMID: 2515998
- Int J Stem Cells.
- 2021 May;14(2):221-228.
- doi: 10.15283/ijsc20096
Background and Objectives: Hypoxia is frequently used to enhance stem cell function. However, the optimal level of hypoxia for growth and function of human embryonic stem cell-derived mesenchymal stem cells... -
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- The Role of Nkx3.1 in Cancers and Stemness
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Antao AM, Ramakrishna S, Kim KS
- KMID: 2515993
- Int J Stem Cells.
- 2021 May;14(2):168-179.
- doi: 10.15283/ijsc20121
The well-known androgen-regulated homeobox gene, NKX3.1, is located on the short arm of chromosome 8. It is the first known prostate epithelium-specific marker, and is a transcription factor involved in... -
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- Distinct Repopulation Activity in Hu-Mice between CBand LPB-CD34＋ Cells by Enrichment of Transcription Factors
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Han AR, Lee JE, Lee MJ, Ko SY, Shin HS, Lee JY, Lee DR
- KMID: 2515996
- Int J Stem Cells.
- 2021 May;14(2):203-211.
- doi: 10.15283/ijsc21015
Background and Objectives: Human CD34＋hematopoietic stem cells can reconstitute the human hematopoietic system when transplanted into immunocompromised mice after irradiation. Human leukapheresis peripheral blood (LPB)-and cord blood (CB)-derived CD34＋ cells... -
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- Valproic Acid Enhance Reprogramming of Bactrian Camel Cells through Promoting the Expression of Endogenous Gene c-Myc and the Process of Angiogenesis
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Li Z, Ge W, Li Y, Zhang Y, Zhao X, Hu J
- KMID: 2515995
- Int J Stem Cells.
- 2021 May;14(2):191-202.
- doi: 10.15283/ijsc20213
Background and Objectives: Induced pluripotent stem cells (iPSCs) are usually generated by reprogramming differentiated cells through the introduction of specific transcription factors, but this is a difficult and inefficient process. Valproic... -
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- Improved Differentiation Ability and Therapeutic Effect of miR-23a-3p Expressing Bone Marrow-Derived Mesenchymal Stem Cells in Mice Model with Acute Lung Injury
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Zhang P, Liu L, Yao L, Song X
- KMID: 2515999
- Int J Stem Cells.
- 2021 May;14(2):229-239.
- doi: 10.15283/ijsc20136
Background and Objectives: Implantation of bone marrow-derived mesenchymal stem cells (BMSCs) has been recognized as an effective therapy for attenuating acute lung injury (ALI). This study aims to discover microRNA... -
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- Enhancement of Wound Healing by Conditioned Medium of Adipose-Derived Stromal Cell with Photobiomodulation in Skin Wound
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Park IS
- KMID: 2515997
- Int J Stem Cells.
- 2021 May;14(2):212-220.
- doi: 10.15283/ijsc20175
Background and Objectives: The objective of this study was to investigate whether conditioned medium from photobiomodulation (PBM) irradiated adipose-derived stromal cell (ASC) spheroids prior to implanting could stimulate angiogenesis and... -
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