- Statins Inhibited the ADP-Stimulated Activation of Integrins alpha v beta5 and alpha v beta3 of Vascular Smooth Muscle Cells
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Joo SJ, Lee SC, Lee JW
- KMID: 2013164
- Korean Circ J.
- 2006 Dec;36(12):809-816.
- doi: 10.4070/kcj.2006.36.12.809
BACKGROUND AND OBJECTIVES: Integrins mediate the migration, adhesion and proliferation of vascular smooth muscle cells. Adenosine diphosphate (ADP) can activate vascular integrins. We assessed the hypothesis that 'statins inhibit the... -
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- Germinal Center Formation and Integrins Expression in the Rat Thymus After 5-Fluorouracil Treatment
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Cho KJ, Han SR, Kim S, Kim SI, Myung PK, Kim MK, Kim WS
- KMID: 1559381
- Korean J Anat.
- 2002 Oct;35(5):431-438.
Thymus is a lymphoid organ forming T-cells from hematogenous stem cells. There is no report on the germinal centers in the thymus except the Myasthenia gravis in human. In this... -
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- The Role of SH2 Domain-containing Leukocyte Phosphoprotein of 76 kDa in the Regulation of Immune Cell Development and Function
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Koretzky G
- KMID: 2150645
- Immune Netw.
- 2009 Jun;9(3):75-83.
- doi: 10.4110/in.2009.9.3.75
Recent years have seen an explosion of new knowledge defining the molecular events that are critical for development and activation of immune cells. Much of this new information has come... -
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- Integrins Mediating Adhesion and Proliferation of ADP-stimulated Vascular Smooth Muscle Cells
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Joo SJ, Cha TJ, Lee JW
- KMID: 2093879
- Korean Circ J.
- 2003 May;33(5):409-419.
- doi: 10.4070/kcj.2003.33.5.409
BACKGROUND AND OBJECTIVES: Adenosine diphosphate (ADP), which is usually secreted from activated platelets, may activate integrins on vascular smooth muscle cells, resulting in adhesion and proliferation. Integrins, mediating the ADP-stimulated... -
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- Adipose-Derived Stem Cell Coculturing Stimulates Integrin-Mediated Extracellular Matrix Adhesion of Melanocytes by Upregulating Growth Factors
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Kim H, Yi N, Do BR, Lee AY
- KMID: 2442010
- Biomol Ther.
- 2019 Feb;27(2):185-192.
- doi: 10.4062/biomolther.2018.203
Coculture with adipose-derived stem cells (ADSCs) can stimulate proliferation and migration of melanocytes. To enhance outcomes of skin disorders caused by melanocyte loss or death, mixed transplantation with ADSCs has... -
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- The Effects of the 3-OH Group of Kaempferol on Interfollicular Epidermal Stem Cell Fate
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Chae JB, Choi HR, Shin JW, Na JI, Huh CH, Park KC
- KMID: 2428925
- Ann Dermatol.
- 2018 Dec;30(6):694-700.
- doi: 10.5021/ad.2018.30.6.694
BACKGROUND: Kaempferol (3,4′,5,7-tetrahydroxyflavone) is a flavonoid known to have a wide range of pharmacological activities. The 3-OH group in flavonoids has been reported to determine antioxidant activities. OBJECTIVE: We tested whether... -
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- Immunohistochemical Expression of Integrins and bcl - 2 in Melanocytic Nevi and malignant Melanomas
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Park JJ, Chung BS
- KMID: 2230632
- Korean J Dermatol.
- 1997 Apr;35(2):234-241.
BACKGROUND: The integrins comprise a family of transmembrane glycoproteins which mediate cell-cell and cell-matr ix intera ctions, and the bcl-2 oncogene is involved in tumorigenesis by blocking apoptosis. Typical acquired... -
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- Inhibition of Transfer Infection of Epstein-Barr Virus to Epithelial Cells by Integrin beta6 siRNA
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Kim SY, Lee SK
- KMID: 2168670
- J Bacteriol Virol.
- 2012 Dec;42(4):346-352.
- doi: 10.4167/jbv.2012.42.4.346
Epstein-Barr virus (EBV) establishes a latent infection in greater than 90% of the world's adult population and associates with various tumors. EBV primarily infects epithelial cells and B cell in... -
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- Stable Expression of Bovine Integrin Beta-6 Increases Susceptibility of Goat Kidney Cell Line to Foot-and-mouth Disease Virus
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Kim SM, Kim SK, Lee KN, Park JH, Kim B
- KMID: 2471836
- J Bacteriol Virol.
- 2020 Mar;50(1):35-43.
- doi: 10.4167/jbv.2020.50.1.035
The integrins αvβ1, αvβ3, αvβ6, and αvβ8 are known to be the natural receptors of foot-and-mouth disease virus (FMDV). Among them, integrin αvβ6 is considered a major receptor for FMDV.... -
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- The effect of telomerase expression on the escape from M2 crisis in virus-transformed human retinal pigment epithelial cells.
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Hwang JH, Park MI, Hwang YY, Yoo HJ, Mardon HJ
- KMID: 1380227
- Exp Mol Med.
- 2002 Jul;34(3):194-200.
Integrins are heterodimeric glycoproteins that have been found to undergo dynamic temporal and spatial changes in the endometrium during the menstrual cycle and in early pregnancy. Specificity of integrins is... -
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- The Patterns of Integrin Subunit Distribution in Glomerular Disease
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Jin DK
- KMID: 2307326
- Korean J Nephrol.
- 1999 May;18(3):380-389.
BACKGROUND: It has been known that integrins are not only simple glue which mediate cell-to-cell or cell to extra-cellular matrix but also function as signaling molecules at the surface... -
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- Molecular Imaging of Angiogenesis
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Lee KH
- KMID: 1469548
- J Korean Med Assoc.
- 2009 Feb;52(2):135-142.
- doi: 10.5124/jkma.2009.52.2.135
Angiogenesis, the process whereby new capillaries are formed by outgrowth from existing microvessels, is required for tumor growth and metastasis, as well as for healing of ischemic injuries. Because angiogenesis... -
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- Expression of Integrin alpha5, alpha6, alphaV, beta1, beta3, beta4 Subunits in Gastric Cancer
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Gham CW, Park SW, Shin Y, Kim HW, Kim HS, Song SY, Chung JB, Kang JK, Noh SH
- KMID: 1864979
- Korean J Gastroenterol.
- 2002 Dec;40(6):355-363.
BACKGROUND/AIMS: The integrins play a central role in maintaining the morphology of cell and tissue, growth, differentiation, migration, survival and apoptosis of cells, and angiogenesis. Although integrins are implicated in... -
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- The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders
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Kang DE, Roh SE, Woo JA, Liu T, Bu JH, Jung AR, Lim Y
- KMID: 2052818
- Exp Neurobiol.
- 2011 Jun;20(2):67-80.
- doi: 10.5607/en.2011.20.2.67
The major defining pathological hallmarks of Alzheimer's disease (AD) are the accumulations of Abeta in senile plaques and hyperphosphorylated tau in neurofibrillary tangles and neuropil threads. Recent studies indicate that... -
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- The Expression of Integrins in Korean Breast Cancer Patients
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Kim H, Jung YS, Kim HJ, Im HH, Lee JW, Byun JS, Kim MW, Park HB
- KMID: 2209586
- J Korean Surg Soc.
- 2003 Jan;64(1):14-19.
PURPOSE: Integrins are cell surface proteins that anchor the cells to the extra-cellular matrix. It has recently been found that integrins are involved in proliferations, migration, differentiation and survival signal... -
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- Leukocyte Adhesion Deficiency Associated with Neonatal Septic Hip in a Late Preterm Infant
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Kim HE, Kim DH, Chung SH, Bae CW, Choi YS
- KMID: 2436138
- Neonatal Med.
- 2018 Nov;25(4):191-195.
- doi: 10.5385/nm.2018.25.4.191
Leukocyte adhesion deficiency is a rare primary immunodeficiency and autosomal recessive disorder caused by a mutation in the gene encoding CD18, which is a constituent of leukocyte integrins. Clinical features... -
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- Expression of alpha3beta1 Integrin in ECV304 Endothelial Cells and Angiogenesis
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Park JS, You BI, Seo CH, Kim SY, Kim EG, Jeong GB
- KMID: 2224556
- Korean J Anat.
- 2000 Aug;33(4):459-470.
Angiogenesis is a fundamental biological process including endothelial cell adhesion, migration, invasion and tube formation. Integrin receptors of endothelial cells play important roles in angiogenesis. They mediate cell-cell contact and... -
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- Presence of E-Cadherin and its Messenger Ribonucleic Acid in Leiomyoma and Myometrium
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Lee KH, Kang KC
- KMID: 2261105
- Korean J Obstet Gynecol.
- 1998 Aug;41(8):2084-2088.
Cell adhesion molecules (CAMs) may be categorized into cadherins, integrins, the immunoglobulin superfamily and others. E-cadherin, a calcium-dependent cell adhesion molecule, is a 120 kDa transmembrane glycoprotein that is localized... -
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- Overexpressions of Vimentin and Integrins in Human Metastatic Spine Tumors
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Park SB, Ryu YJ, Chung YS, Kim CH, Chung CK
- KMID: 1881729
- J Korean Neurosurg Soc.
- 2015 May;57(5):329-334.
- doi: 10.3340/jkns.2015.57.5.329
OBJECTIVE: To comparatively investigate the expression of several integrins in specimens of human bone metastases and degenerative bone tissue. METHODS: Degenerative cancellous tissue was obtained from a sample of human degenerative... -
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- Podocyte Expression of Osteopontin and FSP-1/S100A4 in Human Crescentic Glomerulonephritis
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Yoon GS, Kim TS
- KMID: 1443728
- Korean J Pathol.
- 2011 Jun;45(3):237-246.
- doi: 10.4132/KoreanJPathol.2011.45.3.237
BACKGROUND: Osteopontin (OPN) is a cytokine associated with a cell-matrix via integrins. Fibroblast specific protein-1 (FSP-1), known as S100A4, has been implicated in cell migration by non-muscle myosin. We investigated... -
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