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Antinociceptive Effects of Intraperitoneal and Intrathecal Vitamin E in the Rat Formalin Test

Kim MJ, Hong BH, Zhang EJ, Ko YK, Lee WH

BACKGROUND: Vitamin E is widely known to be one of the reactive oxygen species (ROS) scavengers and a drug that can easily be obtained, and it has been shown to...
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Vitamin E Potentiates the Anti-nociceptive Effects by Intraperitoneal Administration of Lidocaine in Rats

Kim HJ, Yang HJ, Kim SH, Kim DA, Kim SJ, Park HN, Ju JS, Ahn DK

The present study was to evaluate effects of vitamin E on intravenous administration of lidocaine-induced antinociception. Experiments were carried out using male Sprague-Dawley rats. Orofacial formalin-induced nociceptive behavioral responses were...
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Experimental Degeneration of the Rabbits Retina by Sodium Glutamate

Lee HS

  • KMID: 1658396
  • J Korean Ophthalmol Soc.
  • 1972 Sep;13(3):121-126.
Intravitreal and intraperitoneal administrations of sodium L-glutamate induced the retinal degenerations in adult rabbits. Electroretiongram was completely extinguished by the intravitreal injection of glutamate (50mg in 0.1ml) followed by slight...
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Effect of Intraperitoneal and Intravesical Bacillus Calmette-Guerin on Bladder Carcinogenesis in Rats Induced by N-butyl-N-(4-hydroxybutyl) nitrosamine

Kim KM, Kim YK

  • KMID: 2036912
  • Korean J Urol.
  • 1988 Jun;29(3):351-365.
The effects of intraperitoneal injection and intravesical instillation of viable Bacillus Calmette-Guerin(BCG) as an inhibitor in the development of experimental bladder tumors, were examined in rats administered with N-butyl-N-(4-hydroxybutyl) nitrosamine(BBN)....
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The Role of Intraperitoneal Insulin on Liver Regeneration in Rat

Woo YM, Lee KU

  • KMID: 2095210
  • J Korean Surg Soc.
  • 1997 Apr;52(4):473-485.
Insulin is well known to have a hepatotrophic effect, but exogenous insulin has a negative effect on liver regeneration because it decreases the level of endogenous insulin. Howerver intraportal exogenous...
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Comparison of Fos Protein Expressions Rat Hippocampus Following Single and Repeated Intraperitoneal Administration of Kainic Acid

Kim KS, Yoo KM, Chang HK

  • KMID: 1539060
  • J Korean Epilepsy Soc.
  • 1999 Jun;3(1):33-38.
BACKGROUND:Acute seizures that increase neuronal activity cause a rapid and transient induction of the immmediate early c-fos in specific brain regions. C-fos gene may mediate long-term changes in cell function,...
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CT Documentation of Renal Exc retion after Intraperitoneal Administration of Gastrografin in Rats

Sohn KM, Chung SK, Lee SY

PURPOSE: To measure, using spiral CT, the time interval between intraperitoneal injection of gastrografin and its renal excretion, and to demonstrate sequential change in the urinary bladder. MATERIALS AND METHODS:...
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The Effects of Milnacipran on Rat Pain Model

Park SC, Shin SW, Baek SH, Kim HK, Baik SW, Kim KH

BACKGROUND: Serotonin and norepinephrine are known as agents of the nonopiate endogenous descending pain control system. Recently, selective serotonin norepinephrine receptor inhibitors (SNRIs) have been developed as antidepressants. We studied...
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Foreign Body Reaction and Expression of Matrix Metalloproteinases/Tissue Inhibitor of Metalloproteinase by Injection of Mineral Fibers in Rats

Seo DK, Lee JI, Kim JR

  • KMID: 1979063
  • Korean J Pathol.
  • 2011 Dec;45(6):604-611.
BACKGROUND: The host response to natural fibers results in granuloma formation in an effort to limit tissue destruction. Matrix metalloproteinases (MMPs) are important molecules in the inflammatory granulomatous or reparative...
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Participation of Opioid Pathway in the Central Antinociceptive Effects of Eugenol

Kang SH, Kang SW, Kim JH, Kim HY, Ryu HS, Bae SY, Oh JA, Lee JH, Hyun JH, Ahn DK

The aim of the present study was to evaluate the central antinociceptive effects of eugenol after intraperitoneal administration. Experiments were carried out using male Sprague-Dawley rats. Subcutaneous injection of 5%...
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Effects of Dextromethorphan on the Development of Tachyphylaxis to Sciatic Nerve Blockade Induced by 2-Chloroprocaine in the Rat

Park MS, Lee KC, Kim TY

  • KMID: 2104732
  • J Korean Pain Soc.
  • 1996 Jun;9(1):39-45.
Tachyphylaxis to local anesthetics has shown to be promote longer interanalgesic intervals between injections. Previous study demonstrated thermal hyperalgesia accelerates development of tachyphylaxis to sciatic nerve blockade in rats, while...
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Antinociceptive Effect of Memantine and Morphine on Vincristine-induced Peripheral Neuropathy in Rats

Park BY, Park SH, Kim WM, Yoon MH, Lee HG

BACKGROUND: Vincristine-induced peripheral neuropathy is a major dose limiting side effect and thus effective therapeutic strategy is required. In this study, we investigated the antinociceptive effect of memantine and morphine...
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Apoptosis and Ultrastructural Changes of Glomerular Endothelial Cells of Mice with Streptozotocin-induced Diabetic Nephropathy

Kim JS

  • KMID: 1514938
  • Korean J Anat.
  • 2003 Jun;36(3):159-166.
Diabetic nephropathy (DN) in mice induced by intraperitoneal injections of streptozotocin (STZ) three times at divided dosages; the first dosage of 50 mg/kg STZ was given to mice after 12-h...
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Pathogenicitic Characterization of Purified beta-Hemolysin - Produced by Vibrio mimicus

Ju JW, Ju SA

  • KMID: 2001258
  • J Korean Soc Microbiol.
  • 1997 Aug;32(4):371-380.
In order to investigate the main factor of pathogenicity in V. mimicus, we have studied the toxic effects of j3-hemolysin produced by V. mimicus. The purified hemolysin of V. mimicus...
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The Effect of Phosphodiesterase-4-Specific Inhibitor in the Rat Model of Spinal Nerve Ligation

Kim SH, Park BN, Kim SW

OBJECTIVE: Peripheral neuropathy is characterized by hyperalgesia, spontaneous burning pain, and allodynia. The purpose of this study was to investigate the effect of rolipram, a phosphodiesterase-4-specific inhibitor, in a segmental...
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Electron Microscopic Investigation of Finer Structurtes of Rabbit Retina on the Experimental Toxic Lesion

Kim JC

  • KMID: 1665735
  • J Korean Ophthalmol Soc.
  • 1980 Sep;21(3):215-218.
Electron microscopic observation was carried out on the alterations of finer structures of retina following the daily intraperitoneal injections of BRC (benzenhexachloride) and combination of BRC with copper for 4...
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Hepatic Subcapsular Steatosis in a Diabetic CAPD Patient Receiving Intraperitoneal Insulin

Jang EC, Kim G, Kim YS, Yoon SA, Ku YM, Yang CW, Kim YO

Hepatic subcapsular steatosis is a rare and specific form of fatty change in the liver. It is a unique finding in diabetic patients receiving continuous ambulatory peritoneal dialysis (CAPD) and...
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The Effects of Gabapentin on Facial Formalin Test

Kim CH, Baik SW, Kim HK, Kwon JY, Kim KH, Choi SH

BACKGROUND: Gabapentin is a novel anti-epileptic drug, which is used in clinical practice to treat epilepsy. This drug is also used as an analgesic in pain patients. The antinociceptive effect...
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The Effects of Gabapentin on Facial Formalin Test

Kim CH, Baik SW, Kim HK, Kwon JY, Kim KH, Choi SH

BACKGROUND: Gabapentin is a novel anti-epileptic drug, which is used in clinical practice to treat epilepsy. This drug is also used as an analgesic in pain patients. The antinociceptive effect...
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Effect of Sulfhydryl Compounds on Melanosomal Morphology of Epidermal Melanocytes in UV - Irradiated Black Mice

Han KW, Myung KB, Hahm JH, Kook HI

  • KMID: 2231426
  • Korean J Dermatol.
  • 1987 Oct;25(5):553-561.
The present study was performed to evaluate the effect of sulfhydryl compounds, cysteine and glutathione, on the size of melanosomes and the ratio of melanosormai stages of epidermal melanocytes...
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