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Letter: Association between Serum Dipeptidyl Peptidase-4 Concentration and Obesity-Related Factors in Health Screen Examinees (J Obes Metab Syndr 2017;26:188-96)

Koh G

No abstract available.
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The Non-glycemic Effects of SGLT2 Inhibitor

Lee DH

Sodium glucose cotransporter 2 (SGLT2) inhibitors have recently been introduced as a new class of anti-diabetic agents. In addition to their glycemic action, SGLT2 inhibitors also have a number of...
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Clinical Efficacy of Glucagon Like Peptide-1 (GLP-1) Analogues

Chun HJ, Kwon HS

Recently, incretin hormone-based therapies, including glucagon-like peptide-1 (GLP-1) analogues and dipeptidyl peptidase-4 (DPP-4) inhibitors, have become the main therapeutic tools in the hyperglycemia management in patients with type 2 diabetes...
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Changes in Glucose Metabolism with Aging

Hong EG

The increasing risk of glucose intolerance and diabetes associated with aging is well established. However, it is difficult to determine whether changes in glucose metabolism result from biological aging itself...
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Comparison of DPP-4 Inhibitors

Kim NH, Kim SG

During past several years, a novel class of antihyperglycemic agents, dipeptidyl peptidase-4 (DPP-4) inhibitors, has become one of the most important options in the management of type 2 diabetes. These...
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In Vivo Models for Incretin Research: From the Intestine to the Whole Body

Oh TJ

Incretin hormones are produced by enteroendocrine cells (EECs) in the intestine in response to ingested nutrient stimuli. The incretin effect is defined as the difference in the insulin secretory response...
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The Incretins and Pancreatic beta-Cells: Use of Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Polypeptide to Cure Type 2 Diabetes Mellitus

Kim MH, Lee MK

Type 2 diabetes mellitus (T2DM) is increasing in prevalence worldwide. The complications associated with T2DM result in increased mortality and financial cost for those affected. T2DM has long been known...
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Pleiotropic Effects of an Incretin Hormone

Oh S

The incretin hormones glucagon like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) have recently received much attention for their roles in type 2 diabetes therapy. GLP-1 stimulated insulin secretion in...
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Glucose-Lowering Agents in the Management of Nonalcoholic Fatty Liver Disease

Yang H, Park CY

Nonalcoholic fatty liver disease (NAFLD) is more prevalent in diabetic patients than in non-diabetic subjects, because the two diseases share a common pathophysiological mechanism. Associated abnormalities can be observed from...
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Mechanism and Efficacy of New Anti-diabetic Medications

Kwon HS

Previously proposed main pathogenic mechanisms for type 2 diabetes mellitus (T2DM) are increased hepatic glucose production, insulin resistance and insulin secretion defect. However, further mechanisms involved in the development of...
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Response: Association between Serum Dipeptidyl Peptidase-4 Concentration and Obesity-Related Factors in Health Screen Examinees (J Obes Metab Syndr 2017;26:188-96)

Lee JY, Jang BK, Song MK, Kim HS, Kim MK

No abstract available.
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Glucagon-Like Peptide-1 (GLP-1) Agonist

Eom YS, Kim BJ

  • KMID: 2269256
  • Korean J Med.
  • 2014 Jul;87(1):9-13.
The prevalence of diabetes is increasing worldwide. Glycemic control has been shown to prevent microvascular complications. Many oral hyperglycemic drugs and insulin are being used in the treatment of diabetes,...
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Novel Molecules Regulating Energy Homeostasis: Physiology and Regulation by Macronutrient Intake and Weight Loss

Gavrieli A, Mantzoros

Excess energy intake, without a compensatory increase of energy expenditure, leads to obesity. Several molecules are involved in energy homeostasis regulation and new ones are being discovered constantly. Appetite regulating...
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Understanding the Cardiovascular Effects of Incretin

Yoon JS, Lee HW

Cardiovascular disease (CVD), a leading cause of death in patients with diabetes mellitus, has several pathogenic mechanisms that are well established. However, the traditional hypoglycemic agents do not have proven...
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Effect of Nutrient Preload and Food Order on Glucose, Insulin, and Gut Hormones

Bae JH, Cho YM

Postprandial hyperglycemia is associated with the risk of diabetes mellitus, cardiovascular disease, and mortality. Nutrition therapy is an important component of the management of postprandial hyperglycemia. Postprandial glucose levels are...
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Pharmacotherapy for Postprandial Hyperglycemia in Type 2 Diabetes

Yoo HJ

A growing body of evidence shows that effective postprandial hyperglycemia management in individuals with type 2 diabetes can reduce the risk of diabetic complications and cardiovascular diseases. Therefore, accurate monitoring...
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New therapeutic agents in diabetic nephropathy

Kim Y, Park CW

Studies investigating diabetic nephropathy (DN) have mostly focused on interpreting the pathologic molecular mechanisms of DN, which may provide valuable tools for early diagnosis and prevention of disease onset and...
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Comparison of the Efficacy of Dipeptidylpeptidase-4 Inhibitors Between Asian and Non-Asian Populations

Kim YG, Cho YM

Type 2 diabetes is different between Asian and non-Asian populations. Compared with their Caucasian counterparts, Asian patients with type 2 diabetes have the characteristics of lower body mass index, lower...
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New and emerging drugs in type 2 diabetes

Park IB

  • KMID: 2256406
  • Korean J Med.
  • 2007 May;72(5):446-450.
Recent advances in understanding insulin secretion, action and signaling have led to the development of new pharmacological agents. Several new emerging drugs and drug classes for the management of diabetes...
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Clinical Application of Glucagon-Like Peptide-1 Receptor Agonists

Min SH, Cho YM

Glucagon-like peptide 1 (GLP-1) is an incretin hormone that is released from enteroendocrine L-cells upon nutrient absorption; it stimulates glucose-dependent insulin secretion from pancreatic betacells. GLP-1 has pleiotropic effects including...
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