J Korean Diabetes.  2012 Dec;13(4):167-171. 10.4093/jkd.2012.13.4.167.

Mechanism and Efficacy of New Anti-diabetic Medications

• Kwon HS

• KMID: 2173950
• DOI: http://doi.org/10.4093/jkd.2012.13.4.167

Abstract

Previously proposed main pathogenic mechanisms for type 2 diabetes mellitus (T2DM) are increased hepatic glucose production, insulin resistance and insulin secretion defect. However, further mechanisms involved in the development of T2DM such as decreased incretin effect, increased glucose reabsorption and neurotransmitter dysfunction have been proposed recently. Based on these findings, various medications for glycemic control in T2DM are developing. In this review article, I will focus on the mechanisms and efficacies of up-coming new diabetes medications.

Keyword

Type 2 diabetes mellitus; Medication

MeSH Terms

Diabetes Mellitus, Type 2
Glucose
Incretins
Insulin
Insulin Resistance
Neurotransmitter Agents
Glucose
Incretins
Insulin
Neurotransmitter Agents

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