- Host-Pathogen Interactions in Urinary Tract Infections
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Ko YH, Choi JY, Song PH
- KMID: 2467921
- Urogenit Tract Infect.
- 2019 Dec;14(3):71-79.
- doi: 10.14777/uti.2019.14.3.71
Urinary tract infections (UTIs) are classified by the host condition. Uncomplicated infections are caused most commonly by uropathogenic Escherichia coli (UPEC) and affect otherwise healthy people, whereas complicated infections are... -
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- Host immune responses to mycobacterial antigens and their implications for the development of a vaccine to control tuberculosis
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Yuk JM, Jo EK
- KMID: 1730620
- Clin Exp Vaccine Res.
- 2014 Jul;3(2):155-167.
- doi: 10.7774/cevr.2014.3.2.155
Tuberculosis (TB) remains a worldwide health problem, causing around 2 million deaths per year. Despite the bacillus Calmette Guerin vaccine being available for more than 80 years, it has limited... -
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- Immunomodulatory Roles of PE/PPE Proteins and Their Implications in Genomic Features of Mycobacterium tuberculosis
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Choi SY, Shin SJ
- KMID: 2068743
- J Bacteriol Virol.
- 2015 Sep;45(3):272-281.
- doi: 10.4167/jbv.2015.45.3.272
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), remains a notorious cause of human death worldwide. A deeper understanding of the proline-glutamate (PE) and proline-proline-glutamate (PPE) families, which compromise 10% of the... -
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- Role of Intestinal Microbiota in Inflammatory Bowel Diseases
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Eun CS
- KMID: 1974779
- Intest Res.
- 2013 Jul;11(3):161-168.
- doi: 10.5217/ir.2013.11.3.161
A vast number of micro-organisms within the human gut play a crucial role in maintaining human health. Intestinal microbiota maintains the intestinal homeostasis and function by mutually interacting with the... -
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- The Zinc Transport Systems and Their Regulation in Pathogenic Fungi
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Jung WH
- KMID: 2312812
- Mycobiology.
- 2015 Sep;43(3):179-183.
- doi: 10.5941/MYCO.2015.43.3.179
Zinc is an essential micronutrient required for many enzymes that play essential roles in a cell. It was estimated that approximately 3% of the total cellular proteins are required for... -
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- Helicobacter pylori in Human Stomach: Can It Be Called Mutualism or a Disease?
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Cheung DY, Kim TH
- KMID: 1792831
- Korean J Gastroenterol.
- 2012 May;59(5):329-337.
- doi: 10.4166/kjg.2012.59.5.329
Helicobacter pylori (H. pylori) has been a major concern as a gastric pathogen with unique features since discovered in the end of the 20th century. Recent data on comparative genome... -
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- Innate immune response to oral bacteria and the immune evasive characteristics of periodontal pathogens
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Ji S, Choi Y
- KMID: 1783671
- J Periodontal Implant Sci.
- 2013 Feb;43(1):3-11.
- doi: 10.5051/jpis.2013.43.1.3
Periodontitis is a chronic inflammation of periodontal tissue caused by subgingival plaque-associated bacteria. Periodontitis has long been understood to be the result of an excessive host response to plaque bacteria.... -
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- Organoid as a culture system for viral vaccine strains
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Hong KJ, Seo SH
- KMID: 2418093
- Clin Exp Vaccine Res.
- 2018 Jul;7(2):145-148.
- doi: 10.7774/cevr.2018.7.2.145
Organoid is an in vitro multicellular form mimicking in vivo organ. Its similarity to human organ including cellular organization, molecular expression patterns, as well as genetic signatures enables to study... -
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- Development of vaccines to Mycobacterium avium subsp. paratuberculosis infection
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Park HT, Yoo HS
- KMID: 2421557
- Clin Exp Vaccine Res.
- 2016 Jul;5(2):108-116.
- doi: 10.7774/cevr.2016.5.2.108
Johne's disease or paratuberculosis is a chronic debilitating disease in ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). The disease causes significant economic losses in livestock industries worldwide. There are... -
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- Insertional Mutation of ftsH Gene in Streptococcus pneumoniae Causes Stress Sensitivities
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Kim H
- KMID: 2054982
- J Bacteriol Virol.
- 2004 Mar;34(1):9-18.
FtsH is a membrane-bound, ATP-dependent protease involved in various cellular functions. To understand its roles in Streptococcus pneumoniae and host-pathogen interactions, we inactivated the ftsH gene of D39 strain by... -
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- Saprolegnia parasitica Isolated from Rainbow Trout in Korea: Characterization, Anti-Saprolegnia Activity and Host Pathogen Interaction in Zebrafish Disease Model
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Shin S, Kulatunga , Dananjaya , Nikapitiya C, Lee J, De Zoysa M
- KMID: 2401059
- Mycobiology.
- 2017 Dec;45(4):297-311.
- doi: 10.5941/MYCO.2017.45.4.297
Saprolegniasis is one of the most devastating oomycete diseases in freshwater fish which is caused by species in the genus Saprolegnia including Saprolegnia parasitica. In this study, we isolated the... -
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- hpvPDB: An Online Proteome Reserve for Human Papillomavirus
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Kumar S, Jena L, Daf S, Mohod K, Goyal P, Varma AK
- KMID: 2166515
- Genomics Inform.
- 2013 Dec;11(4):289-291.
- doi: 10.5808/GI.2013.11.4.289
Human papillomavirus (HPV) infection is the leading cause of cancer mortality among women worldwide. The molecular understanding of HPV proteins has significant connotation for understanding their intrusion in the host... -
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- Inflammatory Bowel Diseases and Enteric Microbiota
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Kim JM
- KMID: 1775921
- Korean J Gastroenterol.
- 2010 Jan;55(1):4-18.
- doi: 10.4166/kjg.2010.55.1.4
Intestinal mucosal layers are colonized by a complex microbiota that provides beneficial effects under normal physiological conditions, but is capable of contributing to chronic inflammatory disease such as inflammatory bowel... -
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- Comparative Genomics Study of Interferon-alpha Receptor-1 in Humans and Chimpanzees
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Kim IC, Chi SW, Kim DW, Choi SH, Chae SH, Park HS
- KMID: 2284673
- Genomics Inform.
- 2005 Dec;3(4):142-148.
The immune response-related genes have been suggested to be the most favorable genes for positive selection during evolution. Comparing the entire DNA sequence of chimpanzee chromosome 22 (PTR22) with human... -
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- A Serine12Stop mutation in PB1-F2 of the 2009 pandemic (H1N1) influenza A: a possible reason for its enhanced transmission and pathogenicity to humans
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Ramakrishnan MA, Gramer MR, Goyal SM, Sreevatsan S
- KMID: 1726909
- J Vet Sci.
- 2009 Dec;10(4):349-351.
- doi: 10.4142/jvs.2009.10.4.349
As the scientific community scrambles to define the ancestry and lineages of the eight segments of new pandemic H1N1 strain, we looked for unique genetic events in this virus's genome... -
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- Expression patterns of influenza virus receptors in the respiratory tracts of four species of poultry
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Yu JE, Yoon H, Lee HJ, Lee JH, Chang BJ, Song CS, Nahm SS
- KMID: 1067331
- J Vet Sci.
- 2011 Mar;12(1):7-13.
- doi: 10.4142/jvs.2011.12.1.7
The primary determinant of influenza virus infectivity is the type of linkage between sialic acid and oligosaccharides on the host cells. Hemagglutinin of avian influenza viruses preferentially binds to sialic... -
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- Galectins: Double Edged Swords in the Cross-roads of Pregnancy Complications and Female Reproductive Tract Inflammation and Neoplasia
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Than NG, Romero R, Balogh A, Karpati E, Mastrolia , Staretz-Chacham O, Hahn S, Erez O, Papp Z, Kim CJ
- KMID: 2381378
- J Pathol Transl Med.
- 2015 May;49(3):181-208.
- doi: 10.4132/jptm.2015.02.25
Galectins are an evolutionarily ancient and widely expressed family of lectins that have unique glycan-binding characteristics. They are pleiotropic regulators of key biological processes, such as cell growth, proliferation, differentiation,... -
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- Influence of 120 kDa Pyruvate:Ferredoxin Oxidoreductase on Pathogenicity of Trichomonas vaginalis
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Song HO
- KMID: 2374020
- Korean J Parasitol.
- 2016 Feb;54(1):71-74.
- doi: 10.3347/kjp.2016.54.1.71
Trichomonas vaginalis is a flagellate protozoan parasite and commonly infected the lower genital tract in women and men. Iron is a known nutrient for growth of various pathogens, and also... -
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- Entamoeba histolytica Induces Cell Death of HT29 Colonic Epithelial Cells via NOX1-Derived ROS
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Kim KA, Kim JY, Lee YA, Min A, Bahk YY, Shin MH
- KMID: 1501811
- Korean J Parasitol.
- 2013 Feb;51(1):61-68.
- doi: 10.3347/kjp.2013.51.1.61
Entamoeba histolytica, which causes amoebic colitis and occasionally liver abscess in humans, is able to induce host cell death. However, signaling mechanisms of colon cell death induced by E. histolytica... -
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- Genomic assays for Epstein-Barr virus-positive gastric adenocarcinoma
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Gulley ML
- KMID: 2155399
- Exp Mol Med.
- 2015 Jan;47(1):e134.
- doi: 10.1038/emm.2014.93
A small set of gastric adenocarcinomas (9%) harbor Epstein-Barr virus (EBV) DNA within malignant cells, and the virus is not an innocent bystander but rather is intimately linked to pathogenesis... -
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