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The effect of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion

Hwang S, Chung CJ, Choi YJ, Kim T, Kim KH

OBJECTIVE: The objective of this study was to evaluate the effects of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion. METHODS: Sixty male Sprague–Dawley rats were...
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Induction of cell deathin early developmental phase of zebrafish treated with diethylnitrosamine

Kang JS

The purpose of this study was to investigate diethylnitrosamine (DEN)-induced liver damage in zebrafish. Zebrafish larvae were divided into five groups after seventy-two hours fertilization: group 1 (G1) as control,...
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Autophagy localization and cytoprotective role in cisplatin-induced acute kidney injury

Autophagy is a fundamental cellular process that maintains homeostasis and cell integrity, under stress conditions. Although the involvement of autophagy in various conditions has been elucidated, the role of autophagy...
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Dioscorea japonica Thunb. Ethanolic Extract Attenuated Oxazolone-Induced Atopic Dermatitis-like Skin Lesions in BALB/c Mice

Jegal J, Park NJ, Jo BG, Kim SN, Yang MH

The rhizomes of Dioscorea japonica Thunb. are widely consumed as food and also used to treat diabetes and polyuria in Korea. This study was undertaken to study the anti-atopic dermatitis...
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Sentinel Lymph Node Analysis in Colorectal Cancer Patients Using One-Step Nucleic Acid Amplification in Combination With Fluorescence and Indocyanine Green

Esposito F, Noviello A, Moles N, Coppola Bottazzi E, Baiamonte , Macaione I, Ferbo U, Lepore M, Miro A, Crafa F

PURPOSE: Analysis of the sentinel lymph node (SLN) in colorectal cancer (CRC) patients was proposed for more accurate staging and tailored lymphadenectomy. The aim of this study was to assess...
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Stimulatory Effects of KPR-A148 on Osteoblast Differentiation and Bone Regeneration

Lim S, Kim JA, Lee T, Lee D, Nam SH, Lim J, Park EK

BACKGROUND: Xanthine derivatives have been used to treat a variety of medical conditions including respiratory disease and neural degeneration. However, few studies have reported their effects on bone regeneration. Therefore,...
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Comparison of tooth movement and biological response in corticotomy and micro-osteoperforation in rabbits

Kim J, Kook YA, Bayome M, Park JH, Lee W, Choi H, Abbas NH

OBJECTIVE: The aim of this study was to evaluate the amount of tooth movement and histologic changes with different corticotomy designs and micro-osteoperforation in rabbits. METHODS: The sample consisted of 24...
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Exploratory, cognitive, and depressive-like behaviors in adult and pediatric mice exposed to controlled cortical impact

Lee SW, Jang MS, Jeong SH, Kim H

OBJECTIVE: Sequelae of behavioral impairments associated with human traumatic brain injury (TBI) include neurobehavioral problems. We compared exploratory, cognitive, and depressive-like behaviors in pediatric and adult male mice exposed to...
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Evaluation of black glutinous rice (Oryza sativa L) extract as a novel nuclear stain for human sperm head assessment by microscopic examination

Chomean S, Sukanto T, Piemsup A, Chaiya J, Saenguthai K, Kaset C

OBJECTIVE: To compare black rice (Oryza sativa L) extract with three different staining methods for human sperm head assessment. METHODS: Semen samples were collected from 34 volunteers. Four smears of each...
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Development of a mouse model for pulp-dentin complex regeneration research: a preliminary study

Kim S, Lee S, Jung HS, Kim SY, Kim E

OBJECTIVES: To achieve pulp-dentin complex regeneration with tissue engineering, treatment efficacies and safeties should be evaluated using in vivo orthotopic transplantation in a sufficient number of animals. Mice have been...
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Degranulated Eosinophils Contain More Fine Nerve Fibers in the Duodenal Mucosa of Patients With Functional Dyspepsia

Lee MJ, Jung HK, Lee KE, Mun YC, Park S

  • KMID: 2449093
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):212-221.
  • doi: 10.5056/jnm18176
BACKGROUND/AIMS: Functional dyspepsia (FD) is characterized as chronic recurrent upper gastrointestinal symptoms in the absence of any organic disorder. We hypothesized that duodenal low-grade inflammation activates superficial afferent nerve sprouting,...
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Generation of Organotypic Multicellular Spheres by Magnetic Levitation: Model for the Study of Human Hematopoietic Stem Cells Microenvironment

Mejía-Cruz CC, Barreto-Durán E, Pardo-Pérez MA, Jimenez MC, Rincón J, Vanegas K, Rodríguez JL, Jaramillo-Garcia LF, Ulloa JC, Díaz RM, Leal-García E, Pérez-Núñez R, Barreto A, Rodríguez-Pardo VM

BACKGROUND AND OBJECTIVE: The characteristics of human hematopoietic stem cells are conditioned by the microenvironment of the bone marrow, where they interact with other cell populations, such as mesenchymal stem...
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Microelectric Treatment by Transcutaneous Electrical Nerve Stimulation in a Rat Model of Acute Spinal Cord Injury

Sohn HM, Lim W, Kim YW, Ko Y, Park M, Kim B

STUDY DESIGN: Animal study. OBJECTIVES: To investigate the effects of microelectric treatment by transcutaneous electrical nerve stimulation (TENS) on functional recovery and histological changes in a rat model of spinal cord...
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A large thymic mass with persistent active tissue in an elderly cadaver

Tripathy P, Chaudhary , Gaikwad MR, Britto NJ

Thymus is an encapsulated organ having its bilateral origin from the third pharyngeal pouch. It appears to be a single organ but actually it is bilobed. It attains its maximum...
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Short-term changes of human acellular dermal matrix (Megaderm) in a mouse model

Kim YS, Na YC, Yoon HS, Huh WH, Kim JM

BACKGROUND: Physicians tend to overcorrect when applying the acellular dermal matrix for reconstructive option because of volume decrement problem after absorption comparing with initial volume. However, there are no studies...
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Induction of Chondrogenic Differentiation in Human Mesenchymal Stem Cells Cultured on Human Demineralized Bone Matrix Scaffold under Hydrostatic Pressure

Shahmoradi SR, Kabir Salmani M, Soleimanpour HR, Tavakoli A, Hosaini K, Haghighipour N, Bonakdar S

BACKGROUND: Articular cartilage damage is still a troublesome problem. Hence, several researches have been performed for cartilage repair. The aim of this study was to evaluate the chondrogenicity of demineralized...
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Tissue Regeneration of Human Mesenchymal Stem Cells on Porous Gelatin Micro-Carriers by Long-Term Dynamic In Vitro Culture

Nguyen L, Bang S, Noh I

BACKGROUND: Tissue engineering is a multidisciplinary field which attracted much attention in recent years. One of the most important issue in tissue engineering is how to obtain high cell numbers...
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Molluscum Contagiosum of the Eyelid Margin: a Case Series and Literature Review

Jang Y, Kim N, Khwarg SI, Choung HK

PURPOSE: We report 9 cases of molluscum contagiosum of the eyelid margin and a literature review. METHODS: A retrospective, observational case series of 9 patients who were diagnosed with molluscum contagiosum...
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Salivary Duct Cancer Metastasis Mimicking Primary Breast Cancer: A Case Report and Review

Alzuhair A, Gong G, Shin HJ, Lee JW, Lee SB, Kim J, Ko BS, Son BH, Ahn SH, Chung IY

Secondary breast malignancy is a rare occurrence, accounting for less than 2% of all breast malignancies. Salivary duct carcinoma (SDC) metastasizing to the breast has not been reported previously. This...
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Primary Localized Amyloidosis in Extraocular Muscles

Han SH, Kim YD, Woo KI

PURPOSE: Primary localized amyloidosis is a disease characterized by the deposition of abnormal protein fibrils in a specific tissue without systemic involvement. We report a rare case of primary amyloidosis...
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