Ann Dermatol.  1999 Jan;11(1):47-50. 10.5021/ad.1999.11.1.47.

A Case of Nodular Amyloidosis

Abstract

A 38-year-old male patient visited our clinic complaining of three skin lesions on the scalp. There were yellowish to brownish, waxy, non-tender, walnut-sized nodules. Hematoxylin and eosin staining revealed amorphous pinkish material deposits in the dermis. The Congo red stain and Dylon stain under polarizing microscopy showed yellow-green birefringence and the immunoglobulin-lambda light chain stain showed a positive reaction. An electron microscopic examination revealed filaments with uniform diameter(6 to 10nm) that were straight and neither branched nor anastomosed. Based on the clinical, histopathological, immunohistochemical and electron microscopical findings, the skin lesions were diagnosed as nodular amyloidosis.

Keyword

Nodular amyloidosis

MeSH Terms

Adult
Amyloidosis*
Birefringence
Congo Red
Dermis
Eosine Yellowish-(YS)
Hematoxylin
Humans
Male
Microscopy
Scalp
Skin
Congo Red
Eosine Yellowish-(YS)
Hematoxylin
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