- Glycyrrhiza uralensis (licorice) extracts increase cell proliferation and bone marker enzyme alkaline phosphatase activity in osteoblastic MC3T3-E1 cells
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Cho YE, Kwun IS
- KMID: 2419502
- J Nutr Health.
- 2018 Aug;51(4):316-322.
- doi: 10.4163/jnh.2018.51.4.316
PURPOSE: The Glycyrrhiza uralensis species (Leguminosae) as a medicinal biocompound, and one of its root components, isoliquritigenin (ISL), which is a flavonoid, has been reported to have anti-tumor activity in... -
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- In Vitro Anti-Malassezia Activity of Castanea crenata Shell and Oil-Soluble Glycyrrhiza Extracts
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Han SH, Hur MS, Kim MJ, Jung WH, Park M, Kim JH, Shin HJ, Choe YB, Ahn KJ, Lee YW
- KMID: 2378532
- Ann Dermatol.
- 2017 Jun;29(3):321-326.
- doi: 10.5021/ad.2017.29.3.321
BACKGROUND: A new shampoo with anti-Malassezia properties obtained from various plants is required to provide seborrheic dermatitis patients with a wider range of treatment options. OBJECTIVE: The aim of this study... -
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- The Indigenization of Licorice and Its Meaning During the Early Days of the Joseon Dynasty
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Lee KL
- KMID: 2133376
- Korean J Med Hist.
- 2015 Aug;24(2):423-455.
- doi: 10.13081/kjmh.2015.24.423
This article explores the indigenization of licorice(Glycyrrhiza uralensis Fisch.) which was the most important medicine of the Oriental Medicine. There are a lot of records on licorice even before the... -
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- Antibacterial and therapeutic effects of a combination of Sophora flavescens and Glycyrrhiza uralensis Fischer ethanol extracts on mice infected with Streptococcus pyogenes
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Yu EA, Cha CN, Park EK, Yoo CY, Kim S, Lee HJ
- KMID: 1726751
- Korean J Vet Res.
- 2014 Sep;54(3):189-192.
This study evaluated the antibacterial effects of a mixture of Sophorae radix and Glycyrrhiza uralensis Fischer (1 : 1) ethanol extracts (SGE) on mice infected with Streptococcus (S.) pyogenes. The... -
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- Effect of Glycyrrhizin on Rainbow Trout Oncorhynchus mykiss Leukocyte Responses
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Kim KJ, Jang SI, Marsden MJ, Secombes C, Choi MS, Kim YG, Chung HT
- KMID: 1551640
- J Korean Soc Microbiol.
- 1998 Jun;33(3):263-271.
Treatment of rainbow trout macrophages with glycyrrhizin (GL), an aqueous extract of licorice (Glycyrrhiza glabra), enhanced their respiratory burst activity. Maximal effects were seen using concentrations of 10-100 ug/ml. GL... -
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- Antioxidant activities of licorice-derived prenylflavonoids
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Kim HJ, Seo JY, Suh HJ, Lim SS, Kim JS
- KMID: 2313633
- Nutr Res Pract.
- 2012 Dec;6(6):491-498.
Glycyrrhiza uralensis (or licorice) is a widely used Oriental herbal medicine from which the phenylflavonoids dehydroglyasperin C (DGC), dehydroglyasperin D (DGD), and isoangustone A (IsoA) are derived. The purpose of... -
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- Influence of traditional medicines on the activity of keratinocytes in wound healing: an in-vitro study
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Kotian SR, Bhat KM, Padma D, Pai KS
- KMID: 2459548
- Anat Cell Biol.
- 2019 Sep;52(3):324-332.
- doi: 10.5115/acb.19.009
Natural medicinal systems such as Ayurveda and folk medicine has remedies for wound management. However, the exact cellular and extracellular mechanisms involved in the healing process and its influence on... -
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- Comparison of the effect of three licorice varieties on cognitive improvement via an amelioration of neuroinflammation in lipopolysaccharide-induced mice
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Cho MJ, Kim JH, Park CH, Lee AY, Shin YS, Lee JH, Park CG, Cho EJ
- KMID: 2442292
- Nutr Res Pract.
- 2018 Jun;12(3):191-198.
- doi: 10.4162/nrp.2018.12.3.191
BACKGROUND/OBJECTIVES: Neuroinflammation plays critical role in neurodegenerative disorders, such as Alzheimer's disease (AD). We investigated the effect of three licorice varieties, Glycyrhiza uralensis, G. glabra, and Shinwongam (SW) on a... -
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- Inhibition of p65 Nuclear Translocation by KIOM-79
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Kim JS, Jang DS, Jeon YJ, You HJ, Park KH, Ming J, Moon HY, Yoon SP, Chang IY
- KMID: 1937821
- Korean J Anat.
- 2006 Apr;39(2):103-110.
We demonstrate that KIOM-79, combined extracts isolated from Magnolia officinalis, Pueraria lobata, Glycyrrhiza uralensis, and Euphorbia pekinensis, inhibits LPS-induced expression of iNOS gene in RAW 264.7 cells. Treatment of RAW... -
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- Glycyrrhizin Attenuates Kainic Acid-Induced Neuronal Cell Death in the Mouse Hippocampus
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Luo L, Jin Y, Kim ID, Lee JK
- KMID: 1427108
- Exp Neurobiol.
- 2013 Jun;22(2):107-115.
- doi: 10.5607/en.2013.22.2.107
Glycyrrhizin (GL), a triterpene that is present in the roots and rhizomes of licorice (Glycyrrhiza glabra), has been reported to have anti-inflammatory and anti-viral effects. Recently, we demonstrated that GL... -
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- Acute myocardial infarction coincident with gastric ulcer bleeding following herbal medication-induced acute renal failure
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Kang KW, Lee KJ, Yoon HS, Cho YS, Kim SB, Lee S, Jung SH
- KMID: 2259188
- Korean J Med.
- 2010 Mar;78(3):364-369.
Acute renal failure, acute myocardial infarction (AMI), and gastric ulcer bleeding (GUB) are associated with high rates of morbidity and mortality, especially in older patients. The development of each of... -
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- Detection of Inhibitors of beta-Amyloid Peptide Aggregation in Plant Extracts
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Chung MA, Chay KO, Ahn BW
- KMID: 2172400
- Chonnam Med J.
- 2001 Dec;37(4):367-376.
The aggregated beta-amyloid peptides (betaAPs) are suggested to be important in the pathogenesis of Alzheimer's disease. In this study, inhibitory effects of plant extracts on beta-AP aggregation were examined using... -
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- Stimulation of keratinocyte differentiation by extract of combined medicinal plant
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Li XM, Choi DK, Lim SK, Ahn IS, Kim DI, Piao YJ, Kim CD, Lee JH
- KMID: 2168996
- J Biomed Res.
- 2014 Dec;15(4):176-181.
- doi: 10.12729/jbr.2014.15.4.176
Skin is the outermost organ and acts as a barrier between the organism and environment. Skin protects the organism from environmental insults, such as chemicals, pathogens, and UV light. Much... -
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- The use of Stronger Neo-Minophagen C, a glycyrrhizin-containing preparation, in robust neuroprotection in the postischemic brain
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Kim SW, Lim CM, Lee HK, Lee JK
- KMID: 1447444
- Anat Cell Biol.
- 2011 Dec;44(4):304-313.
- doi: 10.5115/acb.2011.44.4.304
Stronger Neo-Minophagen C (SNMC) is a glycyrrhizin-containing preparation that is approved in Japan for the treatment of chronic hepatic diseases and is marketed in Japan, China, Korea, Taiwan, and India.... -
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- The Memory-Enhancing Effects of Liquiritigenin by Activation of NMDA Receptors and the CREB Signaling Pathway in Mice
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Ko YH, Kwon SH, Hwang JY, Kim KI, Seo JY, Nguyen TL, Lee SY, Kim HC, Jang CG
- KMID: 2429049
- Biomol Ther.
- 2018 Mar;26(2):109-114.
- doi: 10.4062/biomolther.2016.284
Liquiritigenin (LQ) is a flavonoid that can be isolated from Glycyrrhiza radix. It is frequently used as a tranditional oriental medicine herbal treatment for swelling and injury and for detoxification.... -
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- Isoliquiritigenin attenuates spinal tuberculosis through inhibiting immune response in a New Zealand white rabbit model
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Wang W, Yang B, Cui Y, Zhan Y
- KMID: 2414261
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):369-377.
- doi: 10.4196/kjpp.2018.22.4.369
Spinal tuberculosis (ST) is the tuberculosis caused by Mycobacterium tuberculosis (Mtb) infections in spinal curds. Isoliquiritigenin 4,2′,4′-trihydroxychalcone, ISL) is an anti-inflammatory flavonoid derived from licorice (Glycyrrhiza uralensis), a Chinese traditional... -
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- Licorice-nduced Hypokalemia and Myopathy
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Suh SC, Uhm MS, Park WW, Koh HI
- KMID: 1597861
- Korean J Nephrol.
- 2006 Jul;25(4):651-655.
Chronic ingestion of licorice or licorice-like compounds induces a syndrome with typical findings of mineralocorticoid excess such as hypertension, hypokalemia, metabolic alkalosis, low plasma renin activity. The only unique feature... -
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- Antagonism of licorice on selectin-mediated eodinophil and neutrophil adhesion
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Kim MK
- KMID: 2286174
- J Asthma Allergy Clin Immunol.
- 1998 Mar;18(1):61-68.
BACKGROUND AND OBJECTIVE: Early in inflammation, adhesion occurs between leukocytes and endothelium where selectins bind to sialyl Lewis x(Sle,) and related oligosaccharides. We tested glycerrhetinic acid(GA), msjor anti-inflammmatory component of licorice, for its... -
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- Electrical storm induced by hypokalemia associated with herbal medicines containing licorice
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Kim HK, Kim SS
- KMID: 2457574
- Transl Clin Pharmacol.
- 2019 Jun;27(2):69-72.
- doi: 10.12793/tcp.2019.27.2.69
A 60-year-old woman presented with polymorphic ventricular tachycardia secondary to hypokalemia, which necessitated dozens of DC cardioversions. She was not taking any other medication and denied any vomiting or diarrhea.... -
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- Whitening Effect of Cosmetics Containing Magnesium L-Ascorbyl-2-Phosphate(VC-PMG, Vitamin C Derivatives) Assessed by Colorimeter
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Park YK, Park YK, Chung WS, Lee H, Jung SW
- KMID: 2158720
- Ann Dermatol.
- 2002 Jun;14(2):63-70.
- doi: 10.5021/ad.2002.14.2.63
BACKGROUNDS: An inhibitory effect of magnesium L-ascorbyl-2-phosphate (VC-PMG, a stable derivative of ascorbic acid) on melanogenesis has been described. Furthermore, glabridin in licorice is known to have inhibitory effects on... -
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