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Association of Serum Adipocyte-Specific Fatty Acid Binding Protein with Fatty Liver Index as a Predictive Indicator of Nonalcoholic Fatty Liver Disease

Jeon WS, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY

BACKGROUND: Adipocyte-specific fatty acid-binding protein (A-FABP) is a cytoplasmic protein expressed in macrophages and adipocytes and it plays a role in insulin resistance and metabolic syndrome. Recently, the fatty liver...
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Association between FABP2 Gene Polymorphism and Energy Metabolism in Normal Korean

Yun SK, Kim CH, Kim YS, Byun DW, Suh KI, Yoo MH, Kim GB

  • KMID: 2331689
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):457-466.
BACKGROUND: The human intestinal fatty acid binding protein (FABP2) locus has been proprosed to be a major candidate gene in determining insulin resistance. It has been hypothesized that alanine to...
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The Role of Urinary Liver-Type Fatty Acid-Binding Protein in Critically Ill Patients

Cho E, Yang HN, Jo SK, Cho WY, Kim HK

Although several urinary biomarkers have been validated as early diagnostic markers of acute kidney injury (AKI), their usefulness as outcome predictors is not well established. This study aimed to determine...
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Tissue Specific Expression of Lipid Metabolism Related Molecules in Digestive Organs of Miniature Pigs

Han HJ, Kang SS, Park SH

  • KMID: 2312077
  • Lab Anim Res.
  • 2010 Sep;26(3):273-278.
The miniature pig is a very suitable donor species in xenotransplantation of human organs. Lipid metabolism is an important process that involves the creation and degradation of lipids, which is...
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Effects of Ethanol in Uptake of Long Chain Fatty Acid in HepG2 Cells

Han NI, Berk PD

  • KMID: 2240629
  • Korean J Gastroenterol.
  • 1998 Apr;31(4):517-524.
Background/Airns: Plasma membrane fatty acid binding protein (FABPpm), a long chain fatty acid (FFA) transporter, is reported to be identical with mitochondrial (m) AST. Alcoholic liver disease (ALD) is characterized...
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Loss of Liver Fatty Acid Binding Protein Expression in Hepatocellular Carcinomas is Associated with a Decreased Recurrence-Free Survival

Kim H, Lee H, Park YN

BACKGROUND/AIMS: Loss of liver fatty acid binding protein (LFABP) expression by immunohis-tochemistry is a useful marker for the identification of hepatocyte nuclear factor 1alpha (HNF1alpha)-inactivated hepatocellular adenomas; however, the expression...
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Polymorphism of the Uncoupling Protein 1 (UCP-1) Gene and Fatty Acid Binding Protein 2 (FABP2) Gene in Korean Type 2 Diabetic Patients

Kim SG, Kim CH, Yun SK, Yun YI, Kim YH, Nam IS, Lee JY, Mok JO, Park HK, Kim YS, Byun DW, Suh KI, Yoo MH

  • KMID: 1567687
  • J Korean Diabetes Assoc.
  • 2001 Aug;25(4):262-272.
BACKGROUND: It is well known that genetic component plays an important role in developing obesity and type 2 diabetes mellitus. A number of candidate genes have been suggested, but the...
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Intestinal barrier integrity and function in infants with cholestasis

Abu Faddan NH, Sherif TM, Mohammed O, Nasif KA, El Gezawy

BACKGROUND/AIMS: The safety of the human body is maintained by effective monitoring of the mucosal surface integrity and protection against potentially harmful compounds. This function of the gut called intestinal...
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Cytokine-like Activity of Liver Type Fatty Acid Binding Protein (L-FABP) Inducing Inflammatory Cytokine Interleukin-6

Kim H, Gil G, Lee S, Kwak A, Jo S, Kim E, Nguyen TT, Kim S, Jhun H, Kim S, Kim M, Lee Y, Kim S

It has been reported that fatty acid binding proteins (FABPs) do not act only as intracellular mediators of lipid responses but also have extracellular functions. This study aimed to investigate...
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Acute Kidney Injury after Using Contrast during Cardiac Catheterization in Children with Heart Disease

Hwang YJ, Hyun MC, Choi BS, Chun SY, Cho MH

Acute kidney injury (AKI) is closely associated with the mortality of hospitalized patients and long-term development of chronic kidney disease, especially in children. The purpose of our study was to...
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Candidates for Tumor Markers of Cervical Cancer Discovered by Proteomic Analysis

Song JY, Bae HS, Koo DH, Lee JK, Jung HH, Lee KW, Lee NW

Cervical cancer is the second most common gynecological cancer among Korean women. While nationwide screening program has developed, the pathogenesis of cervical cancer is unknown. The aim of this study...
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The Prognostic Value of Serum Levels of Heart-Type Fatty Acid Binding Protein and High Sensitivity C-Reactive Protein in Patients With Increased Levels of Amino-Terminal Pro-B Type Natriuretic Peptide

Jeong JH, Seo YH, Ahn JY, Kim KH, Seo JY, Kim MJ, Lee HT, Park PW

BACKGROUND: Amino-terminal pro-B type natriuretic peptide (NT-proBNP) is a well-established prognostic factor in heart failure (HF). However, numerous causes may lead to elevations in NT-proBNP, and thus, an increased NT-proBNP...
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Fasciola gigantica Fatty Acid Binding Protein (FABP) as a Prophylactic Agent against Schistosoma mansoni Infection in CD1 Mice

Aly IR, Diab M, El-Amir AM, Hendawy M, Kadry S

Although schistosomicidal drugs and other control measures exist, the advent of an efficacious vaccine remains the most potentially powerful means for controlling this disease. In this study, native fatty acid...
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Clinicopathological Analysis of Hepatocellular Adenoma According to New Bordeaux Classification: Report of Eight Korean Cases

Kim H, Jang JJ, Kim DS, Yeom BW, Won NH

  • KMID: 2141001
  • Korean J Pathol.
  • 2013 Oct;47(5):411-417.
BACKGROUND: Hepatocellular adenoma (HCA) is a rare benign tumor of the liver. A subtype classification of HCA (hepatocyte nuclear factor 1alpha [HNF1alpha]-mutated, beta-catenin-mutated HCA, inflammatory HCA, and unclassified HCA) has...
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Heart-type Fatty Acid Binding Protein as an Adjunct to Cardiac Troponin-I for the Diagnosis of Myocardial Infarction

Kim KS, Lee HJ, Kim K, Jo YH, Kim TY, Lee JH, Rhee JE, Suh GJ, Kim MR, Lee CC, Singer AJ

We hypothesized that when used in combination with cardiac troponins, heart-type fatty acid binding protein (H-FABP) would have greater diagnostic value than conventional markers for the early diagnosis of myocardial...
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Enhanced A-FABP expression in visceral fat: potential contributor to the progression of NASH

Yoon MY, Sung JM, Song CS, Lee WY, Rhee EJ, Shin JH, Yoo CH, Chae SW, Kim JY, Jin W, Cho YK

BACKGROUND/AIMS: Adipose tissue is an active endocrine organ that secretes various metabolically important substances including adipokines, which represent a link between insulin resistance and nonalcoholic steatohepatitis (NASH). The factors responsible...
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