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Familial Mediterranean fever presenting as fever of unknown origin in Korea

Lee JH, Kim JH, Shim JO, Lee KC, Lee JW, Lee JH, Chae JJ

Familial Mediterranean fever (FMF) is the most common Mendelian autoinflammatory disease, characterized by uncontrolled activation of the innate immune system that manifests as recurrent brief fever and polyserositis (e.g., peritonitis,...
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The First Case of Familial Mediterranean Fever Associated with Renal Amyloidosis in Korea

Koo KY, Park SJ, Wang JY, Shin JI, Jeong HJ, Lim BJ, Lee JS

Familial Mediterranean fever (FMF) is an auto-inflammatory disease characterized by periodic episodes of fever and recurrent polyserositis. It is caused by a dysfunction of pyrin (or marenostrin) as a result...
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Familial Mediterranean Fever With Complete Symptomatic Remission During Pregnancy

Kim KT, Jang HJ, Lee JE, Kim MK, Yoo JJ, Lee GY, Kae SH, Lee J

Familial Mediterranean fever (FMF) is an inherited autosomal recessive disorder, ethnically restricted and commonly found among populations surrounding the Mediterranean Sea. FMF is the most prevalent autoinflammatory disease; is characterized...
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Bloody Diarrhea as a Presentation Manifestation of Familial Mediterranean Fever in a Patient with Compound Heterozygote Mutations of the MEFV Gene

Fallahi GH, Rezaei N, Sadjadei N

  • KMID: 1806652
  • Gut Liver.
  • 2013 Jul;7(4):497-499.
Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease characterized by episodic fever and inflammatory polyserositis, which could lead to a variety of manifestations, including recurrent abdominal pain. Herein, a...
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Familial Mediterranean Fever: The First Adult Case in Korea

Lim AL, Jang HJ, Han JW, Song YK, Song WJ, Woo HJ, Jung YO, Kae SH, Lee J

Familial Mediterranean fever (FMF) is known to be a genetic disorder that prevalent among populations surrounding the Mediterranean Sea. Since Mediterranean fever gene (MEFV) was discovered at 1997, some cases...
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A Case of Recurrent Abdominal Pain with Fever and Urticarial Eruption

Lee CG, Lim YJ, Kang HW, Kim JH, Lee JK, Koh MS, Lee JH, Huh HJ, Lee SH

Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent episodes of fever and serosal, synovial, or cutaneous inflammation, caused by a dysfunction of pyrin as a result...
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Radiologic Findings of Secondary Systemic Amyloidosis Associated with Tuberculosis: A Case Report

Shinn KS, Hahn ST, Kim CY, Lee JM

  • KMID: 2102597
  • J Korean Radiol Soc.
  • 1995 Jul;33(1):97-99.
Amyloidosis is a rare systemic disease caused by extracellular deposition of insoluble protein. Systemic amyloidosis is subclassified into idiopathic primary and secondary form. The cause of secondary amyloidosis includes tuberculosis, familial Mediterranean...
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Extensive Thrombosis in a Patient with Familial Mediterranean Fever, Despite Hyperimmunoglobulin D State in Serum: First Adult Case in Korea

Joo K, Park W, Chung MH, Lim MJ, Jung KH, Heo Y, Kwon SR

Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent episodes of fever accompanied by peritonitis, pleuritis, arthritis, or erysipelas-like erythema. It is known to occur mainly among...
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Can the Thiol/Disulfide Imbalance Be a Predictor of Colchicine Resistance in Familial Mediterranean Fever?

Omma A, Sandikci S, Kücüksahin O, Alisik M, Erel O

Familial Mediterranean fever (FMF) is a chronic autoinflammatory condition characterized by fever attacks and recurrent polyserositis. Subclinical inflammation that persists during attack-free periods can result in oxidative stress (OS) damage....
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A Case of Colchicine Intoxication Presenting as Acute Gastroenteritis

Ahn JY, Sohn YD, Kwon HS, Ahn HC

  • KMID: 2203445
  • J Korean Soc Clin Toxicol.
  • 2008 Dec;6(2):138-141.
A 47-year-old woman ingested about 12 mg of colchicine with suicidal intent. Colchicine, a highly poisonous alkaloid, is a commonly used treatment for gout, Bechet's disease, and familial Mediterranean fever....
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Phagocytic activity in familial Mediterranean fever

Keskin G, Inal A, Sengul A, Cindoruk M, Haznedaroglu S, Duranay M, Songur Y

Familial Mediterranean fever (FMF) is an autosomal recessive disease. Although the possibility of multiple immunologic mechanisms have been studied, the actual mechanism is still unresolved. Forty-one patients with FMF (24...
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Decreased Chitotriosidase Activity and Levels in Familial Mediterranean Fever

Doğan HO, Omma A, Turhan T, Boğdaycıoğlu N, Karaaslan , Yavuz H, Demirpençe O, Aydın H, Bakır S

Different studies have demonstrated changes in chitotriosidase (ChT) activity and concentrations in multiple diseases. However, changes in ChT activity and concentrations have not been concurrently evaluated in patients with Familial...
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Endoscopic Findings of Children with Familial Mediterranean Fever

Sağ E, Demir F, Saygın I, Kalyoncu M, Çakır M

PURPOSE: Familial Mediterranean fever (FMF) is an auto inflammatory disease characterized by periodic fever, synovitis and serositis. Patients may be admitted to gastroenterology units due to gastrointestinal symptoms. In this...
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The role of neutrophil lymphocyte ratio to leverage the differential diagnosis of familial Mediterranean fever attack and acute appendicitis

Kucuk A, Erol MF, Senel S, Eroler E, Yumun HA, Uslu AU, Erol AM, Tihan D, Duman U, Kucukkartallar T, Solak Y

BACKGROUND/AIMS: Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by attacks of fever and diffuse abdominal pain. The primary concern with this presentation is to distinguish it from...
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S1000A12, Chitotriosidase, and Resolvin D1 as Potential Biomarkers of Familial Mediterranean Fever

Taylan A, Gurler O, Toprak B, Sisman AR, Yalcin H, Colak A, Sari I

Familial Mediterranean fever (FMF) is an auto-inflammatory disease characterised by periodic inflammatory attacks. We investigated changes in monocyte-granulocyte derived S10012A and chitotriosidase in both the attack and silent period of...
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Aortic Flow Propagation Velocity in Patients with Familial Mediterranean Fever: an Observational Study

Karaman K, Arisoy A, Altunkas A, Erken E, Demirtas A, Ozturk M, Karayakali M, Sahin S, Celik A

BACKGROUND AND OBJECTIVES: Systemic inflammation has an important role in the initiation of atherosclerosis, which is associated with arterial stiffness (AS). Aortic flow propagation velocity (APV) is a new echocardiographic...
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Pyrin Domain (PYD)-containing Inflammasome in Innate Immunity

Hong S, Park S, Yu JW

Inflammasome is a cytosolic multiprotein complex to activate caspase-1 leading to the subsequent processing of inactive pro-interleukin-1-beta (Pro-IL-1beta) into its active interleukin-1 beta (IL-1beta) in response to pathogen- or danger-associated...
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Duodenal amyloidosis secondary to ulcerative colitis

Park SW, Jee SR, Kim JH, Lee SH, Hwang JW, Jang JG, Lee DW, Seol SY

Amyloidosis is defined as the extracellular deposition of non-branching fibrils composed of a variety of serum-protein precursors. Secondary amyloidosis is associated with several chronic inflammatory conditions, such as rheumatologic or...
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The presence of MEFV gene mutations in patients with primary osteoarthritis who require surgery

Yilmaz S, Erdem H, Tunay S, Torun D, Genc H, Tunca Y, Karadag O, Simsek I, Bahce M, Pay S, Dinc A

BACKGROUND/AIMS: Chronic arthritis of familial Mediterranean fever (FMF) involves weight-bearing joints and can occur in patients without a history of acute attack. Our aim was to investigate a possible causal...
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Can Calprotectin Show Subclinical Inflammation in Familial Mediterranean Fever Patients?

Asan G, Derin ME, DoÄŸan HO, Bayram M, Åžahin M, Åžahin A

BACKGROUND: Familial Mediterranean fever (FMF) is an autoinflammatory disease that has self-limiting inflammatory attacks during polyserositis. Hepcidin is a protein, and interleukin-6 stimulation increases hepcidin levels. Calprotectin (CLP) is a...
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