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Short Bowel Syndrome as the Leading Cause of Intestinal Failure in Early Life: Some Insights into the Management

Goulet O, Abi Nader , Pigneur B, Lambe C

Intestinal failure (IF) is the critical reduction of the gut mass or its function below the minimum needed to absorb nutrients and fluids required for adequate growth in children. Severe...
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Vitamin D Improves Intestinal Barrier Function in Cirrhosis Rats by Upregulating Heme Oxygenase-1 Expression

Wang PF, Yao DH, Hu YY, Li Y

Intestinal barrier dysfunction always accompanies cirrhosis in patients with advanced liver disease and is an important contributor facilitating bacterial translocation (BT), which has been involved in the pathogenesis of cirrhosis...
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Necrotizing Enteritis Caused by Pharyngostomum cordatum Infection in a Stray Cat

Kim JH, Lee K, Sohn WM, Kim HY, Lee YR, Choi EJ, So B, Jung JY

A stray female cat of unknown age, presenting bright red watery diarrhea, was submitted to the Animal and Plant Quarantine Agency for diagnosis. In the small intestines extracted from the...
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Histomorphometric demonstration of the effect of chronic use of nonsteroidal anti-inflammatory drugs–ibuprofen on mucosa of small intestine

Vaidya YP, Tarnekar A, Shende MR

The purpose of this study was to ascertain change in structure of mucosa of small intestine, if any, in small intestine of Swiss albino mice as an effect of chronic...
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Pathogenic and phylogenetic characteristics of non-O157 Shiga toxin-producing Escherichia coli isolates from retail meats in South Korea

Lee JB, Han D, Lee HT, Wi SM, Park JH, Jo JW, Cho YJ, Hahn TW, Lee S, Kang B, Kwak HS, Kim J, Yoon JW

Herein, we report the pathogenic and phylogenetic characteristics of seven Shiga toxin (Stx)-producing Escherichia coli (STEC) isolates from 434 retail meats collected in Korea during 2006 to 2012. The experimental...
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Immunogenicity of the nanovaccine containing intimin recombinant protein in the BALB/c mice

Hosseini Z, Amani J, Baghbani Arani F, Nazarian S, Motamedi M, Shafighian F

PURPOSE: Escherichia coli O157:H7 is one of the most important pathogens which create hemorrhagic colitis and hemolytic uremic syndrome in human. It is one of the most prevalent causes of...
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Maladaptive Behavior and Gastrointestinal Disorders in Children with Autism Spectrum Disorder

Pusponegoro HD, Ismael S, Sastroasmoro S, Firmansyah A, Vandenplas Y

PURPOSE: Various gastrointestinal factors may contribute to maladaptive behavior in children with autism spectrum disorders (ASD). To determine the association between maladaptive behavior in children with ASD and gastrointestinal symptoms...
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A Case of Fanconi-Bickel Syndrome with Mild Clinical Signs

Kim SM, Yoo HW, Kim HW

  • KMID: 2267816
  • Korean J Med.
  • 2013 Aug;85(2):210-213.
Fanconi-Bickel syndrome is a rare autosomal recessive disorder caused by a mutation in the facilitative glucose transporter 2 gene (GLUT2 or SLC2A2 gene) that codes for the glucose transporter protein...
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Intestinal and Hepatic Niemann-Pick C1-Like 1

Park SW

Polytopic transmembrane protein, Niemann-Pick C1-Like 1 (NPC1L1) is localized at the apical membrane of enterocytes and the canalicular membrane of hepatocytes. It mediates intestinal cholesterol absorption and prevents extensive loss...
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Pharmacodynamic Comparison of Two Formulations of Voglibose 0.3-mg Tablet

Kim MJ, Lim HS, Cho SH, Bae KS

  • KMID: 2334543
  • J Korean Soc Clin Pharmacol Ther.
  • 2013 Jun;21(1):34-40.
BACKGROUND: Voglibose, an inhibitor of alpha-glucosidase of the small intestine brush border, is used to treat type 2 diabetic patients. Bioequivalence test based on pharmacokinetic parameters is difficult because voglibose...
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Recent Achievements in Stem Cell Therapy for Pediatric Gastrointestinal Tract Disease

Bae SH

The field of stem cell research has been rapidly expanding. Although the clinical usefulness of research remains to be ascertained through human trials, the use of stem cells as a...
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A review on gastric leptin: the exocrine secretion of a gastric hormone

Cammisotto P, Bendayan M

A major advance in the understanding of the regulation of food intake has been the discovery of the adipokine leptin a hormone secreted by the adipose tissue. After crossing the...
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Stem Cell in Pediatric Gastrointestinal Tract Disease: Hirschsprung Disease

Bae SH

Stem cell is characterized with self-renewal and mult-potency. Many pediatric gastrointestinal diseases have defect in enterocytes, enteric nervous system, and Interstitial cell of Cajal. Various kinds of stem cell could...
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Tufting Enteropathy with EpCAM Mutations in Two Siblings

Ko JS, Seo JK, Shim JO, Hwang SH, Park HS, Kang GH

  • KMID: 1974147
  • Gut Liver.
  • 2010 Sep;4(3):407-410.
Tufting enteropathy is a rare autosomal recessive disorder presenting with early-onset severe intractable diarrhea. The epithelial cell adhesion molecule gene (EpCAM) has recently been identified as the gene responsible for...
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Protective Effects of 5-Androstendiol (5-AED) on Radiation-induced Intestinal Injury

Kim JS, Lee SS, Jang WS, Lee SJ, Park S, Cho SY, Moon C, Kim SH, Kim MS

PURPOSE: We examined the radioprotective effects of 5-androstendiol (5-AED), a natural hormone produced in the reticularis of the adrenal cortex, as a result of intestinal damage in gamma-irradiated C3H/HeN mice. MATERIALS...
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Etoposide-induced Smad6 expression is required for the G1 to S phase transition of the cell cycle in CMT-93 mouse intestinal epithelial cells

Lee YS, Lee EK, Han IO, Park SH

The inhibitory Smad6 and Smad7 are responsible for cross-talk between TGF-beta/bone morphogenic protein (BMP) signaling and other cellular signaling pathways, as well as negative feedback on their own signaling functions....
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Pathotypic Characterization of Enterocyte Effacement-related LEE Genes in EHEC and EPEC Isolated from Diarrheal Patients

Park DH, Moon JY, Kim YB

Attaching and effacing Escherichia coli (AEEC) cause enteric infections in humans and animals. Attaching indicates the intimate attachment of bacteria to the enterocyte, and effacing relates to the localized effacement...
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Identification of a putative cellular receptor 150 kDa polypeptide for porcine epidemic diarrhea virus in porcine enterocytes

Oh JS, Song DS, Park BK

  • KMID: 1089609
  • J Vet Sci.
  • 2003 Dec;4(3):269-275.
Porcine epidemic diarrhea virus (PEDV) causes an acute enteritis in pigs of all ages, often fatality for neonates. PEDV occupies an intermediate position between two well characterized members of the...
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Apoptosis and Gastrointestinal Disease

Kim DG

  • KMID: 1606574
  • Korean J Gastroenterol.
  • 2002 Feb;39(2):79-87.
Apoptosis (programmed cell death) is essential for the normal development and homeostasis of most multi-cellular organism. The morphological and biochemical characteristics of apoptosis are highly conserved during the evolution. This...
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Morphological Changes of the Intestine of the Golden Hamster after Treatment with 6-Aminonicotinamide

Yang YC, Cho BP, Kang HS

  • KMID: 1530292
  • Korean J Anat.
  • 1998 Dec;31(6):887-897.
This study was untertaken to investigate the morphological changes of the intestine of the Golden Hamster after treatment with antimetabolites, 6-aminonicotinamide (6-AN), by light and electron microscopy. 6-AN induced a...
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